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Cited by 62Edible Oils Quality and AnalysisCannabis and Cannabinoid ResearchPhase Equilibria and Thermodynamics

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Effects of supercritical and liquid carbon dioxide extraction on hemp (Cannabis sativa L.) seed oil

Aiello, Alessandra, Pizzolongo, Fabiana, Scognamiglio, Giorgio, Romano, Annalisa, Masi, Paolo, Romano, Raffaele·2020·International Journal of Food Science & Technology
DOI 10.1111/ijfs.14498
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Abstract

Summary: The increase in the popularity of hemp‐based products is mainly linked to the presence of non‐psychoactive cannabinoids that provide relief from aches, pain and anxiety. In this study, hemp seed oils were produced by two innovative and environmentally friendly extraction techniques: supercritical and liquid carbon dioxide (CO 2) extraction. The chemical composition of the two oils was analysed and compared with that of a control oil obtained by solvent (n‐hexane) extraction. Both oils obtained by liquid and supercritical CO 2 extraction presented interesting compositions: they contained large amounts of cannabinoids, polyphenols and tocopherols and were less oxidised than the control and contained a large amount of hexanal, which provided a pleasant aroma. The maximum cannabinoid content was found in the oil obtained by liquid CO 2 extraction (71.51 mg of cannabidiol per kg of oil and 113.92 mg of cannabinol per kg of oil). Carotenoids were prevalent in the oil obtained by supercritical CO 2 extraction (61.00 mg kg−1 of oil).

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Metadata

Authors
Aiello, A., Pizzolongo, F., Scognamiglio, G., Romano, A., Masi, P., & Romano, R.
Affiliations
University of Naples Federico II (IT)
Corresponding author
Pizzolongo, Fabiana
ORCID
Venue
International Journal of Food Science & Technology
Publisher
Oxford University Press (OUP)
Published
2020-01-17
Volume
55
Issue
6
Pages
2472-2480
ISSN
  • 0950-5423 (ISSN-L)
  • 1365-2621
DOI
10.1111/ijfs.14498
OpenAlex
W2998721673
Cited by
62
References
33
Citations by year
2026: 10 · 2025: 12 · 2024: 6 · 2023: 9 · 2022: 14 · 2021: 9 · 2020: 2
FWCI
2.45
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
International Journal of Food Science & Technology (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
  • Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
  • Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Phase Equilibria and Thermodynamics
Keywords
hemp oil, Cannabis sativa, supercritical CO2 extraction, hexane extraction, cannabinoids, cannabidiol, cannabinol, polyphenols, tocopherols, hexanal, carotenoids, oil oxidation, extraction method comparison

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CoChat. (2026). Citation check: Effects of supercritical and liquid carbon dioxide extraction on hemp (Cannabis sativa L.) seed oil. https://app.cochat.ai/papers/10.1111/ijfs.14498
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Aiello, A., Pizzolongo, F., Scognamiglio, G., Romano, A., Masi, P., & Romano, R. (2020). Effects of supercritical and liquid carbon dioxide extraction on hemp (Cannabis sativa L.) seed oil. International Journal of Food Science & Technology. https://doi.org/10.1111/ijfs.14498