Something’s got to give: Time-cost trade-offs in site-specific research approval can negatively impact patient recruitment in multi-institutional studies

Sansom‐Daly, Ursula M.; Evans, Holly E.; Ellis, Sarah J.; McGill, Brittany C.; Hetherington, Kate; Wakefield, Claire E.

doi:10.1111/imj.13535

Cited by 10Ethics in Clinical ResearchHealth and Medical Research ImpactsStatistical Methods in Clinical Trials

Something’s got to give: Time-cost trade-offs in site-specific research approval can negatively impact patient recruitment in multi-institutional studies

Sansom‐Daly, Ursula M., Evans, Holly E., Ellis, Sarah J., McGill, Brittany C., Hetherington, Kate, Wakefield, Claire E.·2017·Internal Medicine Journal

DOI 10.1111/imj.13535

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Launching the trial at eight sites (including securing separate ethical/governance approvals for each hospital) took longer than anticipated.
“Mirroring our experiences with other similar studies [82], launching the trial at eight sites (including securing separate ethical/governance approvals for each hospital) took longer than anticipated.”
From Providing psychological support to parents of childhood cancer survivors: ‘cascade’ intervention trial results and lessons for the future (2021) · cites this paper as [82]

Online group-based cognitive-behavioural therapy for adolescents and young adults after cancer treatment: A multicenter randomised controlled trial of Recapture Life-AYA
Sansom-Daly, U. M., Wakefield, C. E., Bryant, R. A., Butow, P., Sawyer, S., Patterson, P., Anazodo, A., Thompson, K., & Cohn, R. J. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-339 · Cited by 94 · see citing works
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Participation in psychosocial oncology and quality-of-life research: A systematic review
Wakefield, C. E., Fardell, J. E., Doolan, E. L., Aaronson, N. K., Jacobsen, P. B., Cohn, R. J., & King, M. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30100-6 · Cited by 89 · see citing works
Self-citation
Ethical and Clinical Challenges Delivering Group‐based Cognitive‐Behavioural Therapy to Adolescents and Young Adults with Cancer Using Videoconferencing Technology
Sansom‐Daly, U. M., Wakefield, C. E., McGill, B. C., & Patterson, P. (2015) · Australian Psychologist · doi:10.1111/ap.12112 · Cited by 43 · see citing works
Self-citation
Inconsistencies and time delays in site‐specific research approvals hinder collaborative clinical research in Australia
WHITE, V. M., Bibby, H., Green, M., Anazodo, A. C., Nicholls, W., Pinkerton, R., Phillips, M. B., Harrup, R. A., Osborn, M. P., Orme, L. M., et al. (2016) · Internal Medicine Journal · doi:10.1111/imj.13191 · Cited by 34 · see citing works
The Reality of Relapse: Impact of Cancer Relapse on Survivorship Interventions and Patient-Reported Outcomes Data
Sansom‐Daly, U. M., McGill, B. C., Anazodo, A. C., Plaster, M., Maguire, F., O'Dwyer, C., Ellis, S. J., Robertson, E. G., Cohn, R. J., & Wakefield, C. E. (2016) · Pediatric Blood & Cancer · doi:10.1002/pbc.26001 · Cited by 4 · see citing works
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Online, Group-Based Psychological Support for Adolescent and Young Adult Cancer Survivors: Results from the Recapture Life Randomized Trial
Sansom‐Daly, U. M., Wakefield, C. E., Ellis, S. J., McGill, B. C., Donoghoe, M. W., Butow, P. N., Bryant, R. A., Sawyer, S. M., Patterson, P., Anazodo, A. C., et al. (2021) · Cancers · doi:10.3390/cancers13102460 · Cited by 67 · see citing works
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Feasibility, acceptability, and safety of the Recapture Life videoconferencing intervention for adolescent and young adult cancer survivors
Sansom‐Daly, U. M., Wakefield, C. E., Bryant, R. A., Patterson, P., Anazodo, A. C., Butow, P. N., Sawyer, S. M., McGill, B. C., Evans, H. E., Cohn, R. J., et al. (2018) · Psycho-Oncology · doi:10.1002/pon.4938 · Cited by 62 · see citing works
Self-citation
Providing psychological support to parents of childhood cancer survivors: ‘cascade’ intervention trial results and lessons for the future
Wakefield, C. E., Sansom-Daly, U. M., McGill, B. C., Hetherington, K., Ellis, S. J., Robertson, E. G., Donoghoe, M. W., McCarthy, M., Kelada, L., Girgis, A., et al. (2021) · Cancers · doi:10.3390/cancers13225597 · Cited by 28 · see citing works
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Heeding the psychological concerns of young cancer survivors: a single-arm feasibility trial of CBT and a cognitive behavioral conceptualization of distress
Hagström, J., Ander, M., Cernvall, M., Ljótsson, B., Wiman, H., von Essén, L., & Woodford, J. (2020) · PeerJ · doi:10.7717/peerj.8714 · Cited by 15 · see citing works
Challenges in obtaining research ethics and governance approvals for an Australian national intersector, multisite audit study
Buck, K., Nolte, L., Kelly, H., Detering, K. M., Sinclair, C., White, B. P., & Sellars, M. (2020) · Australian Health Review · doi:10.1071/ah20022 · Cited by 14 · see citing works
Author reply
WHITE, V. M., Anazodo, A. C., Pinkerton, R., & on behalf of the Australian AYA POC Study Investigators (2017) · Internal Medicine Journal · doi:10.1111/imj.13540 · Cited by 4 · see citing works
Have centralised ethics and governance applications improved the time‐variable, and approval process to conduct research in Victorian hospitals?
Baguley, B. J., Jefford, M., Aly, A., Cashin, P., & WHITE, V. M. (2019) · Internal Medicine Journal · doi:10.1111/imj.14276 · Cited by 3 · see citing works
How to streamline the low and negligible research ethics and governance review process from 80 to 10 days: submission to decision
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Barriers and hurdles delaying governance approval for an ethically approved nationwide clinical trial in pancreatic cancer
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Author reply
Sansom‐Daly, U. M., Wakefield, C. E., Hetherington, K., Evans, H. E., Ellis, S. J., McGill, B. C., & Cohn, R. J. (2019) · Internal Medicine Journal · doi:10.1111/imj.14320
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Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays
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Authors: Sansom‐Daly, U. M., Evans, H. E., Ellis, S. J., McGill, B. C., Hetherington, K., & Wakefield, C. E.
Affiliations: UNSW Sydney (AU)
ORCID: Sansom‐Daly, Ursula M.
Evans, Holly E.
Ellis, Sarah J.
McGill, Brittany C.
Hetherington, Kate
Wakefield, Claire E.
Venue: Internal Medicine Journal
Publisher: Wiley
Published: 2017-09
Volume: 47
Issue: 9
Pages: 1088-1089
ISSN: 1444-0903 (ISSN-L)
1445-5994
DOI: 10.1111/imj.13535
OpenAlex: W2753703436
Cited by: 10
References: 5
Citations by year: 2024: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 9 d)
Locations: Internal Medicine Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Keywords: time-cost trade-off, research approval, patient recruitment, research ethics committees
MeSH terms: Costs and Cost Analysis, Humans, Research, Patient Selection

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Something’s got to give: Time-cost trade-offs in site-specific research approval can negatively impact patient recruitment in multi-institutional studies

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