Metabolic regulation of NLRP 3

Cited by (311)

Items 101–200 of 311

1. Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages
   José Marcos Sanches, Laura Migliari Branco, Gustavo Henrique Bueno Duarte, Sônia Maria Oliani, Karina Ramalho Bortoluci, Vanessa Moreira, Cristiane Damas Gil · 2020 · Cells
2. Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis
   Meng Niu, Brenda Morsey, Benjamin G. Lamberty, Katy M. Emanuel, Fang Yu, Rosiris León‐Rivera, Joan W. Berman, Peter J. Gaskill, Stephanie M. Matt, Pawel S. Ciborowski et al. · 2020 · Viruses
3. Obesity-Related Glomerulopathy: From Mechanism to Therapeutic Target
   Lifang Wei, Ye Li, Yue Yu, Minmin Xu, Huilan Chen, Lijie Li, Ting Peng, Kang Zhao, Yongze Zhuang · 2021 · Diabetes Metabolic Syndrome and Obesity
4. Pattern-Recognition Receptors and Immunometabolic Reprogramming: What We Know and What to Explore
   Vijay Kumar, John H. Stewart · 2024 · Journal of Innate Immunity
5. Bone marrow‐derived mesenchymal stem cells microvesicles stabilize atherosclerotic plaques by inhibiting NLRP3‐mediated macrophage pyroptosis
   Yu Lin, Meihan Liu, Enqi Chen, Wei Jiang, Weidong Shi, Zhiyuan Wang · 2020 · Cell Biology International
6. Curcumin protects against rotenone-induced Parkinson's disease in mice by inhibiting microglial NLRP3 inflammasome activation and alleviating mitochondrial dysfunction
   Long Xu, Li-Ping Hao, Jing Yu, Shao-Yuan Cheng, Li Fan, Shou-Mei Ding, Rui Zhang · 2023 · Heliyon
7. The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome
   Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei · 2024 · Clinical and Translational Medicine
8. Ibudilast Attenuates Folic Acid–Induced Acute Kidney Injury by Blocking Pyroptosis Through TLR4-Mediated NF-κB and MAPK Signaling Pathways
   Xue Li, Yu Shan Zou, Yuanyuan Fu, Jia Xing, Kaiyue Wang, Pengzhi Wan, Mo Wang, Xiao‐Yue Zhai · 2021 · Frontiers in Pharmacology
9. AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation
   Xingchen Guo, Sheng Chen, Weiwei Yu, Zhexu Chi, Zhen Wang, Ting Xu, Jian Zhang, Danlu Jiang, Yuxian Guo, Hui Fang et al. · 2021 · FEBS Letters
10. Research progress of hexokinase 2 in inflammatory-related diseases and its inhibitors
    Jinxia Chen, Guirong Li, Dejuan Sun, Hua Li, Lixia Chen · 2023 · European Journal of Medicinal Chemistry
11. Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo
    Yuanyuan Chen, Ruisheng Li, Zhilei Wang, Xiaorong Hou, Chunyu Wang, Yongqiang Ai, Wei Shi, Xiaoyan Zhan, Jiabo Wang, Xiaohe Xiao et al. · 2020 · Cellular Immunology
12. Similarities and Differences: A Comparative Review of the Molecular Mechanisms and Effectors of NAFLD and AFLD
    Pengyi Zhang, Weiya Wang, Min Mao, Ruolin Gao, Wenting Shi, Dongmei Li, Richard Calderone, Bo Sui, Xuewen Tian, Xiangjing Meng · 2021 · Frontiers in Physiology
13. Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice
    Shuangxue Han, Zhijun He, Xia Hu, Xiaoqian Li, Kaixin Zheng, Yingying Huang, Peng Xiao, Qingguo Xie, Jiazuan Ni, Qiong Liu · 2023 · Antioxidants
14. Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis
    Florent Guerville, Marine Vialemaringe, Céline Cognet, P. Duffau, Estibaliz Lazaro, Charles Cazanave, Fabrice Bonnet, Olivier Leleux, Rodrigue Rossignol, Benoı̂t Pinson et al. · 2023 · AIDS
15. Dynasore Alleviates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
    Mengtian Shan, Huimin Wan, Linyu Ran, Jihui Ye, Wang Xie, Jingjing Lu, Xueping Hu, Shengjie Deng, Wenyu Zhang, Miao Chen et al. · 2024 · Drug Design Development and Therapy
16. Coenzyme Q0 inhibited the NLRP3 inflammasome, metastasis/EMT, and Warburg effect by suppressing hypoxia-induced HIF-1α expression in HNSCC cells
    Hsin‐Ling Yang, Che-Wei Chang, Chithravel Vadivalagan, Sudhir Pandey, Siang-Jyun Chen, Chuan-Chen Lee, Jhih‐Hsuan Hseu, You‐Cheng Hseu · 2024 · International Journal of Biological Sciences
17. Exposure of DBP in gestation induces inflammation of testicular Sertoli cells in progeny by activating NLRP3 inflammasomes
    Yuan Zhou, Tan Ma, Minghao Yan, Xiannan Meng, Jiang Wu, Jie Ding, Xiaodong Han, Dongmei Li · 2019 · The Science of The Total Environment
18. All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage
    Ahmad Alatshan, Gergő E. Kovács, Azzam Aladdin, Zsolt Czimmerer, Krisztina Tar, Szilvia Benkő · 2020 · Cells
19. A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses
    Katharina Richard, Kurt H. Piepenbrink, Kari Ann Shirey, Archana Gopalakrishnan, Shreeram C. Nallar, Daniel Prantner, Darren J. Perkins, Wendy Lai, Alexandra Vlk, Vladimir Yu. Toshchakov et al. · 2020 · The Journal of Experimental Medicine
20. The crosstalk between NLRP3 inflammasome and gut microbiome in atherosclerosis
    Xiaonan Zhang, Zongliang Yu, Jiye Chen, Xiaoya Li, Ze-Ping Wang, Min Wu, Longtao Liu · 2022 · Pharmacological Research
21. Fucoidan Supplementation Relieved Kidney Injury and Modulated Intestinal Homeostasis in Hyperuricemia Mice
    Meilan Xue, Ronghuan Du, Yifan Zhou, Yuhan Liu, Yingjie Tian, Yan Xu, Jiayi Yan, Pengzhao Song, Lu Wan, Hongsen Xu et al. · 2024 · Journal of Agricultural and Food Chemistry
22. Picking up a Fight: Fine Tuning Mitochondrial Innate Immune Defenses Against RNA Viruses
    Sourav Dutta, Nilanjana Das, Piyali Mukherjee · 2020 · Frontiers in Microbiology
23. Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors
    Pritam Thapa, Sunil P. Upadhyay, Vikas Singh, Varun Chandra Boinpelly, Jianping Zhou, David K. Johnson, Prajwal Gurung, Eung Seok Lee, Ram Sharma, Mukut Sharma · 2022 · European Journal of Medicinal Chemistry Reports
24. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s Disease
    Manikandan Samidurai, Prashant Tarale, Chelva Janarthanam, Crystal Gomez-Estrada, Richard Gordon, Gary D. Zenitsky, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy · 2020 · Cells
25. Anaphylactic degranulation by mast cells requires the mobilization of inflammasome components
    Andrea Mencarelli, Pradeep Bist, Hae Woong Choi, Hanif Javanmard Khameneh, Alessandra Mortellaro, Soman N. Abraham · 2024 · Nature Immunology
26. Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin
    Shupeng Hu, Qiangzhong Pi, Minghao Luo, Zhe Cheng, Xiaoxue Liang, Suxin Luo, Yong Xia · 2021 · International Immunopharmacology
27. Based on molecular structures: Amyloid-β generation, clearance, toxicity and therapeutic strategies
    Hai Yang, Jin‐Ping Li, Xiaoxiong Li, Linqiu Ma, Mingliang Hou, Huadong Zhou, Rui Zhou · 2022 · Frontiers in Molecular Neuroscience
28. Shizhifang ameliorates pyroptosis of renal tubular epithelial cells in hyperuricemia through inhibiting NLRP3 inflammasome
    Jiabao Zhou, Chuanxu Wang, Xuming Zhang, Zhiyuan Wu, Yansheng Wu, Dong‐Dong Li, Jiandong Gao · 2023 · Journal of Ethnopharmacology
29. Mitochondrial-related effects of pentabromophenol, tetrabromobisphenol A, and triphenyl phosphate on murine BV-2 microglia cells
    Christine A Bowen, Gabrielle M. Childers, Caroline E. Perry, Negin P. Martin, Christopher A. McPherson, Tatlock H. Lauten, Janine Hertzog Santos, Gaylia Jean Harry · 2020 · Chemosphere
30. Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF‐κB/NLRP3 Axis
    Tao Wang, Yanbin Gao, Rongchuan Yue, Xiaolei Wang, Yimin Shi, Jiayi Xu, Bingjie Wu, Yimeng Li · 2020 · Evidence-based Complementary and Alternative Medicine
31. Inflammasome-Induced Osmotic Pressure and the Mechanical Mechanisms Underlying Astrocytic Swelling and Membrane Blebbing in Pyroptosis
    Zihui Zheng, Tingting Wang, Jiahui Chen, Huimin Qiu, Chencheng Zhang, Weizhen Liu, Simiao Qin, Jilai Tian, Jun Guo · 2021 · Frontiers in Immunology
32. Melatonin Ameliorates the Progression of Alzheimer’s Disease by Inducing TFEB Nuclear Translocation, Promoting Mitophagy, and Regulating NLRP3 Inflammasome Activity
    Fan Li, Zhaohong Xie, Xiangxue Wang, Yingying Xu, Zhang Xiao, Zhou Xiaoyan, Yan Jieke, Chao Lai · 2022 · BioMed Research International
33. Homogeneous Polyporus Polysaccharide Inhibit Bladder Cancer by Resetting Tumor-Associated Macrophages Toward M1 Through NF-κB/NLRP3 Signaling
    Chunping Liu, Dongyue He, Shihui Zhang, Huiqi Chen, Jie Zhao, Xiong Li, Xing Ziggy Zeng · 2022 · Frontiers in Immunology
34. NLRP3 inflammasome: A potential therapeutic target to minimize renal ischemia/reperfusion injury during transplantation
    Xiaochen Su, Bin Liu, Shangguo Wang, Yu-Xiong Wang, Zehua Zhang, Honglan Zhou, Faping Li · 2022 · Transplant Immunology
35. Overnutrition-induced gout: An immune response to NLRP3 inflammasome dysregulation by XOD activity increased in quail
    Hao Wu, Yu Wang, Zhixin Ren, Yaolei Li, Jingjian Huang, Zhijian Lin, Bing Zhang · 2022 · Frontiers in Immunology
36. An association between mitochondria and microglia effector function: what do we think we know?
    Gaylia Jean Harry, Gabrielle M. Childers, Sahana Giridharan, Irisyunuel Lopez Hernandes · 2020 · Neuroimmunology and Neuroinflammation
37. Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide
    Melanie C. McKell, Rebecca R. Crowther, Stephanie Schmidt, Michelle C. Robillard, Rachel Cantrell, Maria A. Lehn, Edith M. Janssen, Joseph E. Qualls · 2021 · Frontiers in Immunology
38. NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation—Potential Influence on the Myocardium
    Marina Sokolova, Trine Ranheim, Mieke C. Louwe, Bente Lise Halvorsen, Arne Yndestad, Pål Aukrust · 2019 · Journal of Cardiovascular Pharmacology
39. Recent advances in NLRP3 inflammasome in corneal diseases: Preclinical insights and therapeutic implications
    Jiayun Ge, Xiang Li, Yutong Xia, Zhitong Chen, Chen Xie, Yuan Zhao, Ye Shen, Ye Shen, Jianping Tong · 2024 · The Ocular Surface
40. NLRP3 inflammasome mediates angiotensin II-induced islet β cell apoptosis
    Jin Wang, Yan-Jin Feng, Haiyan Huo, Xumei Zhang, Jiping Yue, Wenting Zhang, Zi Yan, Xiangying Jiao · 2019 · Acta Biochimica et Biophysica Sinica
41. Effect of Increased IL-1β on Expression of HK in Alzheimer’s Disease
    Shuangxue Han, Zhijun He, Cornelius Jacob, Xia Hu, Xiao Liang, Wenchang Xiao, Lu Wan, Peng Xiao, Nicola D’Ascenzo, Jiazuan Ni et al. · 2021 · International Journal of Molecular Sciences
42. Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NF-κB/NLRP3 Pathway
    Xiaoxiao Du, Weitao Que, Xin Hu, Xiao Yu, Wen-Zhi Guo, Shuijun Zhang, Xiao‐Kang Li · 2021 · Frontiers in Immunology
43. Uric acid–driven NLRP3 inflammasome activation triggers lens epithelial cell senescence and cataract formation
    Hong-Liang Lin, Wang Sheng, Kota Sato, Yu Qiao Zhang, Bei Ting He, Jing Xu, Toru Nakazawa, Yongjie Qin, Hongyang Zhang · 2024 · Cell Death Discovery
44. Isoliquiritigenin Alleviates Diabetic Kidney Disease via Oxidative Stress and the TLR4/NF‐κB/NLRP3 Inflammasome Pathway
    Yanhong Wang, Jia Hui Yang, Xinyue Chang, Yuan Xue, Gaohong Liu, Tingting Zhang, Weihao Chen, Weiping Fan, Jihua Tian, Xiaojun Ren · 2024 · Molecular Nutrition & Food Research
45. Neutrophil extracellular traps induce trophoblasts pyroptosis via enhancing NLRP3 lactylation in SLE pregnancies
    Haoyue Hu, You Peng, Chi Chiu Wang, Jun Chen, Xiaoyan Yu, Xiaoyan Chen, Haotong Ouyang, Qin Huang, Jing Ma, Qian Yin et al. · 2025 · Journal of Autoimmunity
46. Elevated serum uric acid level is associated with adverse reproductive outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization or intracytoplasmic sperm injection embryo transfer cycles: a retrospective cohort study
    Haiyan Yang, Guiquan Wang, Chang Liu, Lin Ding, Yan Li, Yi Chen, Yili Teng, Zhihui Xu, Zhenhong Ye, Yue Zhao et al. · 2022 · American Journal of Obstetrics and Gynecology
47. The role of glial cells in Zika virus‐induced neurodegeneration
    André Quincozes‐Santos, Larissa Daniele Bobermin, Naithan Ludian Fernandes Costa, Natalie K. Thomaz, Rômulo Rodrigo de Souza Almeida, Walter O. Beys‐da‐Silva, Lucélia Santi, Rafael Lopes da Rosa, Daniela Capra, Juliana M. Coelho‐Aguiar et al. · 2023 · Glia
48. The NLRP3 inflammasome regulates corneal allograft rejection through enhanced phosphorylation of STAT3
    Chao Wei, Li Ma, Hao Chi, Li Lin, Sai Zhang, Wenhui Yin, Ting Liu, Hua Gao, Weiyun Shi · 2020 · American Journal of Transplantation
49. Nrf2 Inhibits the Progression of Parkinson’s Disease by Upregulating AABR07032261.5 to Repress Pyroptosis
    Yunxiao Zhong, Xiaodong Cai, Li Ding, Jinchi Liao, Xu Liu, Yiying Huang, Xiaohong Chen, Ling Long · 2022 · Journal of Inflammation Research
50. Recent Advances in Reactive Oxygen Species (ROS)-Responsive Polyfunctional Nanosystems 3.0 for the Treatment of Osteoarthritis
    Dao-Fang Ding, Yan Xue, Xi‐Chen Wu, Zhi-Heng Zhu, Jia-Ying Ding, Yong-Jia Song, Xiaoling Xu, Jian‐Guang Xu · 2022 · Journal of Inflammation Research
51. Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated-pyroptosis
    Layla A. Al‐Kharashi, Hala Attia, Aljazzy Alsaffi, Toka Almasri, Maha Arafa, Iman H. Hasan, Hanaa N. Alajami, Rehab Ali, Amira Mohamed Badr · 2023 · Toxicology and Applied Pharmacology
52. Serum Uric Acid Predicts All-Cause and Cardiovascular Mortality Independently of Hypertriglyceridemia in Cardiometabolic Patients without Established CV Disease: A Sub-Analysis of the URic acid Right for heArt Health (URRAH) Study
    Alessandro Mengozzi, Nicola Riccardo Pugliese, Giovambattista Desideri, Stefano Masi, Fabio Angeli, Carlo Maria Barbagallo, Michele Bombelli, Federica Cappelli, Edoardo Casiglia, Rosario Cianci et al. · 2023 · Metabolites
53. Cyclic helix B peptide alleviates sepsis-induced acute lung injury by downregulating NLRP3 inflammasome activation in alveolar macrophages
    Xuepeng Zhang, Weitao Zhang, Yue Qiu, Min‐Jie Ju, Cheng Yang, Guo-Wei Tu, Zhe Luo · 2020 · International Immunopharmacology
54. A novel mechanism for NLRP3 inflammasome activation
    Tan Zhang, Jingyao Zhao, Tiemin Liu, Wei Cheng, Yibing Wang, Shuzhe Ding, Ru Wang · 2022 · Metabolism Open
55. Nrf2 Inhibits the Progression of Parkinson’s Disease by Upregulating AABR07032261.5 to Repress Pyroptosis
    Yunxiao Zhong, Xiaodong Cai, Ding L, Jinchi Liao, Xu Liu, Yiying Huang, Chen X, Ling Long · 2022 · DOAJ (DOAJ: Directory of Open Access Journals)
56. A gain-of-function NLRP3 3′-UTR polymorphism causes miR-146a-mediated suppression of NLRP3 expression and confers protection against sepsis progression
    Furong Lu, Hongpeng Chen, Yuan Hong, Yao Lin, Lizhen Liu, Ning Wei, Qinyan Wu, Shuanglin Liao, Shuai Yang, Junbing He et al. · 2021 · Scientific Reports
57. Ketone bodies as chemical signals for the immune system
    Michelangelo Bauwelz Gonzatti, Emily L. Goldberg · 2024 · American Journal of Physiology-Cell Physiology
58. Macrophage fatty acid oxidation in atherosclerosis
    Sujun Xiao, Mingxu Qi, Qinyi Zhou, Hui-Qin Gong, Duhui Wei, Guangneng Wang, Qilun Feng, Zhou Wang, Zhe Liu, Yiren Zhou et al. · 2023 · Biomedicine & Pharmacotherapy
59. Hyperuricemia drives intestinal barrier dysfunction by regulating gut microbiota
    Xiaomin Yang, Dan Liu, Xiangzhong Zhao, Yafei Han, Xiaoran Zhang, Quan Zhou, Qiulan Lv · 2024 · Heliyon
60. A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring
    Gretchen L. Seim, Jing Fan · 2022 · Trends in Endocrinology and Metabolism
61. LncRNA NEAT2 Modulates Pyroptosis of Renal Tubular Cells Induced by High Glucose in Diabetic Nephropathy (DN) by via miR-206 Regulation
    Amal Ezzat Abd El-Lateef, Adel Galal El-Shemi, Mona S. Alhammady, Rucui Yuan, Yan Zhang · 2022 · Biochemical Genetics
62. Not Just an Alternative Energy Source: Diverse Biological Functions of Ketone Bodies and Relevance of HMGCS2 to Health and Disease
    Varshini V. Suresh, Sathish Sivaprakasam, Yangzom Doma Bhutia, Puttur Devi Prasad, Muthusamy Thangaraju, Vadivel Ganapathy · 2025 · Biomolecules
63. Recombinant Treponema pallidum protein Tp47 promoted the phagocytosis of macrophages by activating NLRP3 inflammasome induced by PKM2 ‐dependent glycolysis
    Yun‐Wen Zheng, Meihong Wang, J.‐W. Xie, Rong Chen, Xiaomin Wang, Yi He, Tian‐Ci Yang, Li‐Li Liu, Li‐Rong Lin · 2023 · Journal of the European Academy of Dermatology and Venereology
64. CD80+ dendritic cell derived exosomes inhibit CD8+ T cells through down-regulating NLRP3 expression after liver transplantation
    Bin Cui, Jie Sun, Shipeng Li, Guang‐Peng Zhou, Xiaojie Chen, Li‐Ying Sun, Lin Wei, Zhi‐Jun Zhu · 2022 · International Immunopharmacology
65. Copper deficiency is an independent risk factor for mortality in patients with advanced liver disease
    Lei Yu, Sarim Muhammad Yousuf, Shahrukh Yousuf, Jeffrey Yeh, Scott W. Biggins, Chihiro Morishima, Irene Shyu, Galen P O’Shea-Stone, Brian J. Eilers, Annie Waldum et al. · 2023 · Hepatology Communications
66. RAGE deficiency obstructs high uric acid-induced oxidative stress and inflammatory response
    Hairong Zhao, Jiamin Lv, Binyang Chen, Furong He, Qiang Wang, De Xie, Hidenori Koyama, Chenggui Zhang, Jidong Cheng · 2025 · International Immunopharmacology
67. White matter damage in Alzheimer’s disease: contribution of oligodendrocytes
    Zhou, Jinyu, Zhang, Peng, Zhang, Bo, Kong, Yuhan · 2022 · Current Alzheimer Research
68. Oridonin attenuates liver ischemia–reperfusion injury by suppressing PKM2/NLRP3-mediated macrophage pyroptosis
    Xinyi Wu, Min-jie Zhao, Wei Liao, Tao Liu, Jun-Yan Liu, Jun-hua Gong, Xing Lai, Xuesong Xu · 2024 · Cellular Immunology
69. HIV-TAT dysregulates microglial lipid metabolism through SREBP2/miR-124 axis: Implication of lipid droplet accumulation microglia in NeuroHIV
    Cheng, Yan, Jung, Jaekeun, Guo, Liyang, Shuboni-Mulligan, Dorela D., Chen, Jian-Fu, Hu, Wenhui, Guo, Ming-Lei · 2025 · Brain, Behavior, and Immunity
70. Targeting hexokinase 1 alleviates NLRP3‐mediated inflammation in apical periodontitis: A laboratory investigation
    Yajie Qian, Deyan Chen, Yanan Zhu, Jing Wu, Yong Wang, Wei-dong Yang · 2023 · International Endodontic Journal
71. Integrative network fusion-based multi-omics study for biomarker identification and patient classification of rheumatoid arthritis
    Zihe Ding, Wenjia Chen, Hao Wu, Weijie Li, Xia Mao, Weiwei Su, Yanqiong Zhang, Na Lin · 2023 · Chinese Medicine
72. Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis
    Jarmila Sekeresova Kralova, Ales Drobek, Jan Procházka, František Špoutil, Matej Fabišik, Daniela Glatzová, Šimon Borna, Jana Pokorna, Tereza Skopcova, Pavla Angelisová et al. · 2020 · The Journal of Immunology
73. Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds
    Gabrielle M. Childers, Caroline A. Perry, Barbara Blachut, Negin P. Martin, Carl D. Bortner, Stella O. Sieber, Jian‐Liang Li, Michael B. Fessler, Gaylia Jean Harry · 2021 · Environmental Health Perspectives
74. Glutamine limits NLRP3 inflammasome activation and pyroptosis in macrophages by sustaining the IRG1 /itaconate axis
    Xiaoli Chen, Yuanfeng Zhu, Lin Xia, Sen Su, Shijun Fan, Yongling Lu, Qian Chen, Wei Yan, Qianying Huang, Xin Liu et al. · 2025 · FEBS Journal
75. PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity
    Zemeng Ma, Yuxuan Wu, Zebing Rao, Chenhua Han, Naishuang Sun, Jinzhou Li, Qiang Zeng, Zaikui Zhang, Ding Ding, Jiajun Qiao et al. · 2025 · Cell Reports
76. Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation
    Xiaoling Li, Yiming Liu, Chengyu Luo, Jin‐Hui Tao · 2022 · Frontiers in Pharmacology
77. The effect of neuroinflammation on the cerebral metabolism at baseline and after neural stimulation in neurodegenerative diseases
    Fatima Cheataini, Nissrine Ballout, Tareq Al Sagheer · 2023 · Journal of Neuroscience Research
78. NLRP3 as a sensor of metabolism gone awry
    Emilia Neuwirt, Oliver Gorka, Benedikt S. Saller, Christina J. Groß, Tobias Madl, Olaf Groß · 2021 · Current Opinion in Biotechnology
79. BRD4 inhibition by JQ1 protects against LPS-induced cardiac dysfunction by inhibiting activation of NLRP3 inflammasomes
    Wenjun Li, XiuFeng Shen, Shenglan Feng, Yue Liu, Huiying Zhao, Guohao Zhou, Ming Sang, Xiaodong Sun, Rong Jiao, Fuyuan Liu · 2022 · Molecular Biology Reports
80. Lung Inflammasome Activation in SARS-CoV-2 Post-Mortem Biopsies
    Lucas Baena Carstens, Raíssa Campos D’Amico, Karen Fernandes de Moura, Eduardo Morais de Castro, Flávia Centenaro de Oliveira, Giovanna Silva Barbosa, Guilherme Vieira Cavalcante da Silva, Isadora Drews Brenny, Júlio César Honório D’Agostini, Elisa Carolina Hlatchuk et al. · 2022 · International Journal of Molecular Sciences
81. p16INK4a Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin
    Yan Liang, Tianya Gu, Su Peng, Yi Lin, JiaBao Liu, Xiaoyan Wang, Xin Huang, Xiaodong Zhang, Jun Zhu, Lin Zhao et al. · 2022 · Oxidative Medicine and Cellular Longevity
82. A Proteomics- and Metabolomics-Based Study Revealed That Disorder of Palmitic Acid Metabolism by Aconitine Induces Cardiac Injury
    Chenghao Bi, Tianpu Zhang, Yamei Li, Huan Zhao, Pengjie Zhang, Yuming Wang, Yanyan Xu, Kun Gu, Yuechen Liu, Jiao Yu et al. · 2020 · Chemical Research in Toxicology
83. Mitochondrial dysfunction–induced PANoptosis: Mechanisms, triggers, and disease implications
    Liyang Pan, Shijie Fang, Fanhua Kong, Shaojun Ye, Yan Xiong · 2026 · Mitochondrion
84. Association between serum uric acid and female infertility: a cross-sectional study of National Health and Nutrition Examination Survey (NHANES) 2013–2018
    Luo Chen, Haiying Cheng, Xiao He, Xiaojun Tan, Xianghong Huang · 2023 · BMC Women s Health
85. Degrasyn alleviates osteoarthritis by blocking macrophagic pyroptosis via suppressing NLRP3/GSDMD signaling pathway and protecting chondrocytes
    Shujun Xie, Linqiao Wang, Congcong Lu, Hao Chen, Yi Ding, Xu Jian, Zhen Zhang, Liulong Zhu · 2024 · Cellular Signalling
86. Effects and underlying mechanisms of food polyphenols in treating gouty arthritis: A review on nutritional intake and joint health
    Fengmao Zou, Xiaofang Li, Rong Yang, Ruowen Zhang, Xu Dong Zhao · 2022 · Journal of Food Biochemistry
87. Macrophage-targeted shikonin-loaded nanogels for modulation of inflammasome activation
    Matias Cardoso, Vítor M. Gaspar, Carolina Ferreira, Ricardo Silvestre, Iola F. Duarte, João Filipe Mano · 2022 · Nanomedicine Nanotechnology Biology and Medicine
88. A novel strategy for bioactive natural products targeting NLRP3 inflammasome in Alzheimer’s disease
    Zhiyou Yang, Junxin Liu, Shuai Wei, Jiahang Deng, Xinyue Feng, Shucheng Liu, Mingxin Liu · 2023 · Frontiers in Pharmacology
89. Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation
    Wenqing Mu, Guang Xu, Zhilei Wang, Qiang Li, Siqiao Sun, Qin Qin, Zhiyong Li, Wei Shi, Wenzhang Dai, Xiaoyan Zhan et al. · 2023 · Cell Communication and Signaling
90. Role of oxidants and antioxidants in diabetic wound healing
    Manuela M. Martins‐Green, Shayan Saeed · 2020 · Elsevier eBooks
91. Mechanism of miR-126 in hypoxia-reoxygenation-induced cardiomyocyte pyroptosis by regulating HMGB1 and NLRP3 inflammasome
    Ling Fei, Ning Zhang, Jun Zhang · 2022 · Immunopharmacology and Immunotoxicology
92. Edaravone protects against liver fibrosis progression via decreasing the IL-1β secretion of macrophages
    Rongrong Zhao, Huajun Zhao, Quanjuan Guo, Yongliang Mu, Jian Zhang, Yuhang Su, Qiuju Han · 2022 · Chemico-Biological Interactions
93. The HO-1 Signal Prevents HMGB1-Mediated Activation of NLRP3 Inflammasomes in Lipopolysaccharide-Induced Acute Lung Injury In Vitro
    Man Luo, Xiuqin Hong, Hao Zhu, Guang Li, Li‐Juan Tang · 2019 · Journal of Surgical Research
94. Sex-Specific Signature in the Circulating NLRP3 Levels of Saudi Adults with Metabolic Syndrome
    Nasser M. Al‐Daghri, Kaiser Wani, Hind AlHarthi, Amani Ahmed Alghamdi, Abdullah M. Alnaami, Sobhy M. Yakout · 2021 · Journal of Clinical Medicine
95. ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation
    Danli Kong, Zhenhua Mai, Yongze Chen, Ling Luo, Hao Liu, Zhao Le, Ruixian Huang, Shuang Wang, Rong Chen, Hao Zhou et al. · 2022 · Pharmaceuticals
96. Galangin Targets HSP90β to Alleviate Ulcerative Colitis by Controlling Fatty Acid Synthesis and Subsequent NLRP3 Inflammasome Activation
    Ling Yang, Xing‐yu Ma, Ke‐xin Mu, Yue Dai, Yufeng Xia, Zhifeng Wei · 2023 · Molecular Nutrition & Food Research
97. Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
    Marek Adamowski, Karolina Wołodko, Joana Oliveira, Juan Castillo Fernandez, Daniel Murta, Gavin Kelsey, António Miguel Galvão · 2021 · Frontiers in Cell and Developmental Biology
98. Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
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99. High-Risk Obesity Phenotypes: Target for Multimorbidity Prevention at the ROFEMI Study
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