Evaluating the impact of using a wound‐specific oral nutritional supplement to support wound healing in a rehabilitation setting
Open accessAbstract
Chronic wounds adversely affect patient quality of life, increase the risk of mortality, and impose high costs on healthcare systems. Since protein‐energy malnutrition or specific nutrient deficiencies can delay wound healing, nutritionally focused care is a key strategy to help prevent or treat the occurrence of non‐healing wounds. The objective of our study of inpatients in a rehabilitation hospital was to quantify the effect of daily wound‐specific oral nutritional supplementation (WS‐ONS) on healing chronic wounds. Using electronic medical records, we conducted a retrospective analysis of patients with chronic wounds. We identified records for (a) a treatment group who received standard wound care + usual hospital diet + daily WS‐ONS for ≥14 days, and (b) a control group who received standard wound care + a usual hospital diet. We collected data for demographics, nutritional status, and wound‐relevant health characteristics. We examined weekly measurements of wound number and sizes (surface area for superficial wounds or volume for non‐superficial wounds). There were 341 patients identified, 114 with 322 wounds in the treatment group and 227 patients with 420 wounds in the control group. We found that rehabilitation inpatients who were given nutritional support had larger wounds and lower functional independence on admission. At discharge, wound area reduction (percent) was nearly two‐fold better in patients who were given daily WS‐ONS + usual hospital diet compared to those who consumed usual diet only (61.1% vs 34.5%). Overall, weekly wound improvement (lowered wound area or wound volume) was more likely in the WS‐ONS group than in the Control group, particularly from the start of care to week 2. Inpatients with largest wounds and lowest functional independence on admission were most likely to be given WS‐ONS, an indication that caregivers recognised the need for supplementation. Week‐to‐week improvement in wound size was more likely in patients who received WS‐ONS than in those who did not. Specifically, wound areas and wound volumes were significantly lower at discharge among patients who were given specialised nutritional support. More research in this field is needed to improve care and reduce healthcare costs.
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A supportive retrospective analysis of data collected from 341 patients showed that daily provision of wound-specific ONS resulted in a significantly greater decrease in wound area, compared to patients who did not receive nutritional support (61.1% in the intervention group vs 34.5% in the control group, p=0.01).
“A supportive retrospective analysis of data collected from 341 patients showed that the daily provision of wound-specific ONS resulted in a significant greater decrease in the wound area, compared to the patients who did not receive nutritional support (61.1% in the IG vs. 34.5% in the CG, p ¼ 0.01) [42].”
From ESPEN guideline on nutritional support for polymorbid medical inpatients (2023) · cites this paper as [42]
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Cited by
Sorted by citations
ESPEN guideline on nutritional support for polymorbid medical inpatients
Wunderle, C., Gomes, F., Schuetz, P., Stumpf, F., Austin, P., Ballesteros-Pomar, M. D., Cederholm, T., Fletcher, J., Laviano, A., Norman, K., et al. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.06.023 · Cited by 105 · see citing works
“…retrospective analysis of data collected from 341 patients showed that the daily provision of wound-speci fi c ONS resulted in a signi fi cant greater decrease in the wound area, compared to the patients who did not receive nutritional support (61.1% in the IG vs. 34.5% in the CG, p ¼ 0.01) [42].”
Influential
- Authors
- Clark, R. K., Stampas, A., Kerr, K. W., Nelson, J. L., Sulo, S., Leon‐Novelo, L., Ngan, E., & Pandya, D.
- Affiliations
- Memorial Hermann Institute for Rehabilitation and Research Foundation (US)
- Scientific and Medical Affairs Abbott Laboratories Columbus Ohio USA
- School of Public Health University of Texas Health Science Center at Houston Houston Texas USA
- The University of Texas Health Science Center at Houston (US)
- Corresponding author
- Kerr, Kirk W.
- Venue
- International Wound Journal
- Publisher
- Wiley
- Published
- 2022-06-09
- Volume
- 20
- Issue
- 1
- Pages
- 145-154
- ISSN
- 1742-4801 (ISSN-L)
- 1742-481X
- PMC
- PMC9797929
- OpenAlex
- W4281996690
- Cited by
- 24
- References
- 0
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 6 · 2023: 5 · 2022: 2
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Wound Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Commons-TMC (Texas Medical Center) (submittedVersion)
- Funders
- Abbott Laboratories
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Health Sciences › Health Professions › Occupational Therapy › Pressure Ulcer Prevention and Management
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Keywords
- chronic wounds, wound healing, nutritional support, rehabilitation inpatients, protein-energy malnutrition, wound size reduction, functional independence, nutritional status
- MeSH terms
- Humans, Nutritional Status, Quality of Life, Retrospective Studies, Wound Healing, Dietary Supplements, Malnutrition
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