Cited by 41

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Dendritic cells, DRiPs, and DALIS in the control of antigen processing

Pierre, Philippe·2005·Immunological Reviews

Abstract

Summary: The study of the cell biology of antigen processing and presentation has greatly contributed to our understanding of the immune response. The work of many immunologically inclined cell biologists has also permitted new insights into cellular mechanisms shared by many cell types. Here are described recent and particularly exciting findings on the regulation of major histocompatibility complex class I‐restricted presentation in dendritic cells and their contribution to the deciphering of the cellular response to pathogen detection.

Overview

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Crossref · 10.1111/j.0105-2896.2005.00300.x

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  • A reduction in SQSTM1 levels in NP40/Triton X-100 lysates does not necessarily indicate that SQSTM1 is degraded, because SQSTM1 aggregates are insoluble in these detergent lysis conditions.

    “However, this does not necessarily indicate that SQSTM1 is degraded, because SQSTM1 aggregates are insoluble in these detergent lysis conditions [421, 612].”
  • SQSTM1 may be transcriptionally upregulated under some conditions, as observed in several C. elegans longevity models, further complicating interpretation.

    “SQSTM1 may be transcriptionally upregulated under some conditions [421, 565-568], as observed in several C. elegans longevity models [569, 570], further complicating the interpretation of results.”

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Metadata

Authors
Pierre, P.
Venue
Immunological Reviews
Publisher
Wiley
Published
2005-09-23
Volume
207
Issue
1
Pages
184-190
ISSN
  • 0105-2896
  • 1600-065X
Cited by
41
References
1
Language
en

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