A CLINICAL DIAGNOSTIC INDEX IN THE DIAGNOSIS OF THE DUMPING SYNDROME: Changes in Plasma Volume and Blood Sugar after a Test Meal
Abstract
On the basis of the literature and personal analysis of symptoms and signs in 25 gastrectomized patients, new criteria for the dumping syndrome have been outlined. The clinical diagnosis of the dumping syndrome was based upon a clinical diagnostic index. The method was then applied to 49 partially gastrectomized patients. It is stressed that three of the cardinal symptoms may easily be overlooked, viz. sleepiness, dizziness, and restlessness. Eructation and vomiting are components of the afferent loop syndrome and the small stomach syndrome. After a test meal of hypertonic glucose the percentage changes in plasma volume were measured by Evans blue, hematocrit, and hemoglobin values. All three methods revealed statistically significant differences between dumpers and non‐dumpers as regards the mean values of the percentage fall in plasma volume. An increasing fall in plasma volume was generally parallelled by a rising clinical diagnostic index. All patients who showed a fall in plasma volume above 15% were dumpers. Women showed a greater fall in plasma volume and a distinctly larger clinical diagnostic index than men. Statistically significant differences were found between dumpers and non‐dumpers as regards the rise in blood sugar after the test meal.
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A diagnostic index >7 is suggestive of dumping syndrome whereas a score <4 suggests that other diagnoses should be considered.
“A diagnostic index >7 is suggestive of dumping syndrome whereas a score <4 suggests that other diagnoses should be considered.”
From Dumping syndrome after esophageal, gastric or bariatric surgery: Pathophysiology, diagnosis, and management (2017) · cites this paper as [31]
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Service, G. J., Thompson, G. B., Service, F. J., Andrews, J. C., Collazo-Clavell, M. L., & Lloyd, R. V. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043690 · Cited by 779 · see citing works
Pathophysiology, diagnosis and management of postoperative dumping syndrome
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“The Sigstad’s scoring system assigns points to each dumping symptom, and the total points are used to calculate a diagnostic index (31).”
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Postprandial GLP-1, Norepinephrine, and Reactive Hypoglycemia in Dumping Syndrome
Gebhard, B., Holst, J. J., Biegelmayer, C., & Miholic, J. (2001) · Digestive Diseases and Sciences · doi:10.1023/a:1010635131228 · Cited by 92 · see citing works
A Possible Role of GLP-1 in the Pathophysiology of Early Dumping Syndrome
Yamamoto, H., Mori, T., Tsuchihashi, H., Akabori, H., Naito, H., & Tani, T. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-3046-2 · Cited by 43 · see citing works
Basbug, A., Ellibeş Kaya, A., Dogan, S., Pehlivan, M., & Goynumer, G. (2019) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2018.1471678 · Cited by 28 · see citing works
- Authors
- Sigstad, H.
- Affiliations
- University of Bergen (NO)
- Corresponding author
- Sigstad, Helge
- Venue
- Acta Medica Scandinavica
- Publisher
- Wiley
- Published
- 1970-01-12
- Volume
- 188
- Issue
- 1-6
- Pages
- 479-486
- ISSN
- 0001-6101 (ISSN-L)
- OpenAlex
- W4317564262
- Cited by
- 176
- References
- 0
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 8 · 2023: 12 · 2022: 11 · 2021: 15 · 2020: 17 · 2019: 8 · 2018: 6 · 2017: 12 · 2016: 9 · 2015: 7 · 2014: 4 · 2013: 4 · 2012: 3
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Medica Scandinavica (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gastric Cancer Management and Outcomes
- Keywords
- dumping syndrome, gastrectomy, partial gastrectomy, plasma volume, Evans blue, postprandial hypoglycemia, sleepiness, dizziness, restlessness, sex differences, hematocrit, hemoglobin
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