Does pregnancy interval after laparoscopic sleeve gastrectomy affect maternal and perinatal outcomes?
Open accessAbstract
Background: Obesity is a global health epidemic and is associated with many maternal and neonatal complications. Laparoscopic sleeve gastrectomy (LSG) is among the surgical treatments for obesity. The appropriate timing of pregnancy following LSG remains controversial and few studies have evaluated this public health issue.Objective: To evaluate the effect of pregnancy timing after LSG on maternal and perinatal outcomes.Study design: We performed a retrospective observational study of 23 pregnant women who underwent LSG at a tertiary hospital in Turkey. Women who became pregnant within 18 months of undergoing LSG were included in the early pregnancy after LSG group, and those who became pregnant after 18 months were included the late pregnancy after LSG group. Maternal and perinatal outcomes were evaluated, including gestational diabetes mellitus (GDM), pregnancy-associated hypertensive disorders, preterm birth, mode of delivery, small and large for gestational age births (small for gestational age (SGA), large for gestational age (LGA)), birth injury, and congenital malformations.Results: Body mass index (BMI) at conception was higher in the early pregnancy after LSG group than in the late pregnancy after LSG group (30.48 versus 27.25, respectively; p = .03). Pregnancy interval after LSG did not impact maternal–fetal complications or mode of delivery. After a 75 g oral glucose tolerance test (OGTT) for GDM, 75% (n = 6) of the early pregnancy group presented with early dumping syndrome, compared to only 13.3% (n = 2) of the late pregnancy after LSG group (p = .009).Conclusions: LSG may reduce obesity-related gestational complications, such as GDM and LGA. The interval between LSG and conception did not impact maternal or neonatal outcomes. Screening for GDM can result in dumping syndrome in pregnancies after LSG.
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Delaying pregnancy after bariatric surgery was associated with a trend towards lower odds for admission in the neonatal intensive care unit (OR 0.73, 95% CI 0.45 to 1.18).
“Delaying pregnancy was associated with a trend towards lower odds for admission in the neonatal intensive care unit (OR 0.73, 95% 0.45 to 1.18).”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [133]
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- Authors
- Basbug, A., Ellibeş Kaya, A., Dogan, S., Pehlivan, M., & Goynumer, G.
- Affiliations
- Department of Obstetrics and Gynecology, Duzce University, Faculty of Medicine
- Department of General Surgery, Duzce University, Faculty of Medicine
- Department of Obstetrics and Gynecology, SB Istanbul Medeniyet University Goztepe Education and Research Hospital
- Venue
- The Journal of Maternal-Fetal & Neonatal Medicine
- Publisher
- Informa UK Limited
- Published
- 2018-05-17
- Volume
- 32
- Issue
- 22
- Pages
- 3764-3770
- ISSN
- 1476-4954 (ISSN-L)
- 1476-7058
- OpenAlex
- W2800895703
- Cited by
- 28
- References
- 36
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 7 · 2019: 5
- FWCI
- 4.45
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- Locations
- The Journal of Maternal-Fetal & Neonatal Medicine (publishedVersion)
- PubMed (publishedVersion)
- DSpace - Düzce (Duzce University) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- laparoscopic sleeve gastrectomy, pregnancy timing, interpregnancy interval, maternal outcomes, perinatal outcomes, gestational diabetes mellitus, dumping syndrome, obesity, preterm birth, large for gestational age, mode of delivery, congenital malformations
- MeSH terms
- Adolescent, Adult, Birth Intervals, Female, Gastrectomy, Humans, Infant, Newborn, Male, Middle Aged, Obesity, Morbid, Parity, Laparoscopy, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Retrospective Studies, Turkey, Young Adult
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