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Cited by 71Diabetes Management and ResearchDiabetes Treatment and ManagementDiabetes Management and Education

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

The Stockholm Diabetes Intervention Study (SDIS): 18 Months' Results

REICHARD, PER, BRITZ, ANDERS, CARS, ISOLDE, NILSSON, BENGT Y., SOBOCINSKY‐OLSSON, BIRGITTA, ROSENQVIST, URBAN·1988·Acta Medica Scandinavica
DOI 10.1111/j.0954-6820.1988.tb16748.x
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Abstract

Patients with insulin-dependent diabetes mellitus (IDDM), non-proliferative retinopathy and unsatisfactory blood glucose control were randomized to intensified conventional treatment (ICT, 48 patients) or regular treatment (RT, 54 patients) for a 5-year study. After 18 months the glycosylated hemoglobin (HbA1c) was reduced in both groups, but significantly more in the ICT group (p = 0.00005). Thirty of the RT patients and 16 from the ICT group deteriorated as to retinopathy (p = 0.024). Microalbuminuria appeared more often in the RT patients (p = 0.023), and nerve conduction velocities were significantly reduced only in the RT group (p between 0.0005 and 0.047). Serious hypoglycemia was more common in the ICT patients (p = 0.003). The progression of diabetic late complications was thus slowed down by intensified treatment, but at the price of an increased frequency of serious hypoglycemia.

Overview

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Cites

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Citations

Cites

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Research works printed but not linked: 6

  1. The KROC Collaborative Study Group., 1985, The KROC study patients at two years: a report on further retinal changes, Diabetes, 34, 39 A
  2. 10.2337/diabetes.30.8.700 · doi:10.2337/diabetes.30.8.700
  3. Early Treatment Diabetic Retinopathy Study, 1980, Manual of operations
  4. Blalock HM., 1979, Social statistics
  5. 1983, RS/1 integrated data analysis system for the Professional 350. User's guide
  6. Feldt‐Rasmussen B., 1984, Variability of urinary albumin excretion in incipient diabetic nephropathy, Diab Nephrop, 3, 101

Cited by

See all 71

Metadata

Authors
REICHARD, P., BRITZ, A., CARS, I., NILSSON, B. Y., SOBOCINSKY‐OLSSON, B., & ROSENQVIST, U.
Affiliations
  • Stockholm South General Hospital (SE)
  • Region Stockholm (SE)
Corresponding author
REICHARD, PER
Venue
Acta Medica Scandinavica
Publisher
Wiley
Published
1988-01-12
Volume
224
Issue
2
Pages
115-122
ISSN
0001-6101 (ISSN-L)
DOI
10.1111/j.0954-6820.1988.tb16748.x
OpenAlex
W2138195670
Cited by
71
References
20
Citations by year
2025: 1 · 2024: 1 · 2022: 1 · 2020: 1 · 2018: 2 · 2017: 3 · 2015: 3 · 2014: 7 · 2013: 1 · 2012: 2
FWCI
3.11
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 7773 d)
Locations
  • Acta Medica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords
type 1 diabetes, glycemic control, HbA1c, diabetic retinopathy, retinopathy progression, microalbuminuria, diabetic nephropathy, nerve conduction velocity, diabetic neuropathy, hypoglycemia, diabetes complications
MeSH terms
Adult, Albuminuria, Diabetes Mellitus, Type 1, Diabetic Retinopathy, Glycated Hemoglobin, Humans, Hypoglycemia, Insulin, Middle Aged, Prospective Studies, Random Allocation, Sweden

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CoChat. (2026). Citation check: The Stockholm Diabetes Intervention Study (SDIS): 18 Months' Results. https://app.cochat.ai/papers/10.1111/j.0954-6820.1988.tb16748.x
The paper
REICHARD, P., BRITZ, A., CARS, I., NILSSON, B. Y., SOBOCINSKY‐OLSSON, B., & ROSENQVIST, U. (1988). The Stockholm Diabetes Intervention Study (SDIS): 18 Months' Results. Acta Medica Scandinavica. https://doi.org/10.1111/j.0954-6820.1988.tb16748.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.