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Cited by 46Substance Abuse Treatment and OutcomesAlcoholism and Thiamine DeficiencyOpioid Use Disorder Treatment

Dependence on Sedative‐hypnotics: neuropsychological impairment, field dependence and clinical course in a 5‐year follow‐up study

BERGMAN, HANS, BORG, STEFAN, ENGELBREKTSON, KARIN, VIKANDER, BRITT·1989·British Journal of Addiction
DOI 10.1111/j.1360-0443.1989.tb00612.x
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Abstract

Despite some neuropsychological improvement in a group of 30 patients who had been hospitalized for primary abuse of sedatives or hypnotics 4-6 years earlier, the prevalence of intellectual impairment was still increased and about as high as before. As in alcoholic patients CAT scan of the brain showed an increased prevalence of dilatation of the ventricular system, but unlike alcoholics not of widened cortical sulci. Field dependence and visuo-spatial skills during treatment predicted abuse status at follow-up. Patients with improved drug habits had less pronounced withdrawal symptoms during treatment and a better social situation at follow-up than patients without improvement of drug habits. The results suggest that despite some neuropsychological improvement cerebral disorder diagnosed in patients abusing sedatives or hypnotics is often permanent through the years and that neuropsychological status is linked to long-term prognosis.

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Crossref · 10.1111/j.1360-0443.1989.tb00612.x

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Authors
BERGMAN, H., BORG, S., ENGELBREKTSON, K., & VIKANDER, B.
Affiliations
Karolinska Institutet (SE)
Corresponding author
BORG, STEFAN
ORCID
BORG, STEFAN
Venue
British Journal of Addiction
Publisher
Wiley
Published
1989-05
Volume
84
Issue
5
Pages
547-553
ISSN
  • 0952-0481 (ISSN-L)
  • 2056-5178
DOI
10.1111/j.1360-0443.1989.tb00612.x
OpenAlex
W2010650281
Cited by
46
References
12
Citations by year
2026: 1 · 2025: 1 · 2020: 1 · 2017: 1
FWCI
1.11
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 6112 d)
Locations
  • British Journal of Addiction (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Neurology › Alcoholism and Thiamine Deficiency
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
substance dependence, neuropsychological deficits, intellectual disability, field dependence, visuospatial ability, ventriculomegaly, brain disorders, withdrawal symptoms, long-term prognosis, social functioning, follow-up
MeSH terms
Adult, Aged, Female, Field Dependence-Independence, Follow-Up Studies, Humans, Hypnotics and Sedatives, Male, Middle Aged, Neuropsychological Tests, Substance-Related Disorders

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