The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Motivation and patch treatment for HIV+ smokers: a randomized controlled trial
Open accessAbstract
Aims To test the efficacy of two smoking cessation interventions in a HIV positive (HIV+) sample: standard care (SC) treatment plus nicotine replacement therapy (NRT) versus more intensive motivationally enhanced (ME) treatment plus NRT. Design Randomized controlled trial. Setting HIV+ smoker referrals from eight immunology clinics in the northeastern United States. Participants A total of 444 participants enrolled in the study (mean age = 42.07 years; 63.28% male; 51.80% European American; mean cigarettes/day = 18.27). Interventions SC participants received two brief sessions with a health educator. Those setting a quit date received self‐help quitting materials and NRT. ME participants received four sessions of motivational counseling and a quit‐day counseling call. All ME intervention materials were tailored to the needs of HIV+ individuals. Measurements Biochemically verified 7‐day abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups. Findings Intent‐to‐treat (ITT) abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups were 12%, 9% and 9%, respectively, in the ME condition, and 13%, 10% and 10%, respectively, in the SC condition, indicating no between‐group differences. Among 412 participants with treatment utilization data, 6‐month ITT abstinence rates were associated positively with low nicotine dependence (P = 0.02), high motivation to quit (P = 0.04) and Hispanic American race/ethnicity (P = 0.02). Adjusting for these variables, each additional NRT contact improved the odds of smoking abstinence by a third (odds ratio = 1.32, 95% confidence interval = 0.99–1.75). Conclusions Motivationally enhanced treatment plus NRT did not improve cessation rates over and above standard care treatment plus NRT in this HIV+ sample of smokers. Providers offering brief support and encouraging use of nicotine replacement may be able to help HIV+ patients to quit smoking.
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Metadata
- Authors
- Lloyd‐Richardson, E. E., Stanton, C. A., Papandonatos, G. D., Shadel, W. G., Stein, M., Tashima, K., Flanigan, T., Morrow, K., Neighbors, C., & Niaura, R.
- Affiliations
- University of Massachusetts Dartmouth (US)
- Brown University (US)
- RAND Corporation (US)
- National Center on Addiction and Substance Abuse at Columbia University (US)
- Corresponding author
- Lloyd‐Richardson, Elizabeth E.
- ORCID
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 2009-10-09
- Volume
- 104
- Issue
- 11
- Pages
- 1891-1900
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- PMC
- PMC2763031
- OpenAlex
- W2066729021
- Semantic Scholar
- 9872242e227c6abd7ae920d09bf862bf6bcec1b6
- Cited by
- 125
- References
- 36
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 10 · 2020: 2 · 2019: 8 · 2018: 4 · 2017: 4 · 2016: 17 · 2015: 14 · 2014: 10 · 2013: 13 · 2012: 12
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (K23HL069987)
- National Institute on Drug Abuse (R01-DA12344-06, R01DA012344)
- National Cancer Institute (K07CA095623, P50CA084719)
- National Institute of Allergy and Infectious Diseases (P30AI042853)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- smoking cessation, nicotine replacement therapy, motivation enhancement, motivational counseling, nicotine dependence, abstinence rates, brief intervention, Hispanic Americans, race and ethnicity
- MeSH terms
- Administration, Cutaneous, Adult, Black or African American, Counseling, Female, Hispanic or Latino, HIV Seropositivity, Humans, Male, Motivation, New England, Nicotine, Smoking, Program Evaluation, Smoking Cessation, Treatment Outcome, White People
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