Cited by 126Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesBehavioral Health and Interventions

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Motivation and patch treatment for HIV+ smokers: a randomized controlled trial

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Lloyd‐Richardson, Elizabeth E., Stanton, Cassandra A., Papandonatos, George D., Shadel, William G., Stein, Michael, Tashima, Karen, Flanigan, Timothy, Morrow, Kathleen, Neighbors, Charles, Niaura, Raymond·2009·Addiction

DOI 10.1111/j.1360-0443.2009.02623.xPMC PMC2763031

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Abstract

Aims To test the efficacy of two smoking cessation interventions in a HIV positive (HIV+) sample: standard care (SC) treatment plus nicotine replacement therapy (NRT) versus more intensive motivationally enhanced (ME) treatment plus NRT. Design Randomized controlled trial. Setting HIV+ smoker referrals from eight immunology clinics in the northeastern United States. Participants A total of 444 participants enrolled in the study (mean age = 42.07 years; 63.28% male; 51.80% European American; mean cigarettes/day = 18.27). Interventions SC participants received two brief sessions with a health educator. Those setting a quit date received self‐help quitting materials and NRT. ME participants received four sessions of motivational counseling and a quit‐day counseling call. All ME intervention materials were tailored to the needs of HIV+ individuals. Measurements Biochemically verified 7‐day abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups. Findings Intent‐to‐treat (ITT) abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups were 12%, 9% and 9%, respectively, in the ME condition, and 13%, 10% and 10%, respectively, in the SC condition, indicating no between‐group differences. Among 412 participants with treatment utilization data, 6‐month ITT abstinence rates were associated positively with low nicotine dependence (P = 0.02), high motivation to quit (P = 0.04) and Hispanic American race/ethnicity (P = 0.02). Adjusting for these variables, each additional NRT contact improved the odds of smoking abstinence by a third (odds ratio = 1.32, 95% confidence interval = 0.99–1.75). Conclusions Motivationally enhanced treatment plus NRT did not improve cessation rates over and above standard care treatment plus NRT in this HIV+ sample of smokers. Providers offering brief support and encouraging use of nicotine replacement may be able to help HIV+ patients to quit smoking.

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Authors: Lloyd‐Richardson, E. E., Stanton, C. A., Papandonatos, G. D., Shadel, W. G., Stein, M., Tashima, K., Flanigan, T., Morrow, K., Neighbors, C., & Niaura, R.
Affiliations: University of Massachusetts Dartmouth (US)
Brown University (US)
RAND Corporation (US)
National Center on Addiction and Substance Abuse at Columbia University (US)
Corresponding author: Lloyd‐Richardson, Elizabeth E.
ORCID: Lloyd‐Richardson, Elizabeth E.
Stanton, Cassandra A.
Papandonatos, George D.
Shadel, William G.
Stein, Michael
Tashima, Karen
Flanigan, Timothy
Neighbors, Charles
Niaura, Raymond
Venue: Addiction
Publisher: Wiley
Published: 2009-10-09
Volume: 104
Issue: 11
Pages: 1891-1900
ISSN: 0965-2140 (ISSN-L)
1360-0443
DOI: 10.1111/j.1360-0443.2009.02623.x
PMC: PMC2763031
OpenAlex: W2066729021
Semantic Scholar: 9872242e227c6abd7ae920d09bf862bf6bcec1b6
Cited by: 125
References: 36
Citations by year: 2026: 3 · 2025: 1 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 10 · 2020: 2 · 2019: 8 · 2018: 4 · 2017: 4 · 2016: 17 · 2015: 14 · 2014: 10 · 2013: 13 · 2012: 12
FWCI: 5.68
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Addiction (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Heart, Lung, and Blood Institute (K23HL069987)
National Institute on Drug Abuse (R01-DA12344-06, R01DA012344)
National Cancer Institute (K07CA095623, P50CA084719)
National Institute of Allergy and Infectious Diseases (P30AI042853)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
Keywords: smoking cessation, nicotine replacement therapy, motivation enhancement, motivational counseling, nicotine dependence, abstinence rates, brief intervention, Hispanic Americans, race and ethnicity
MeSH terms: Administration, Cutaneous, Adult, Black or African American, Counseling, Female, Hispanic or Latino, HIV Seropositivity, Humans, Male, Motivation, New England, Nicotine, Smoking, Program Evaluation, Smoking Cessation, Treatment Outcome, White People

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Motivation and patch treatment for HIV+ smokers: a randomized controlled trial

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