A randomized clinical trial of smoking cessation treatments provided in HIV clinical care settings
Open accessAbstract
INTRODUCTION: Identifying successful smoking treatment interventions and methods of delivery is critical given the smoking rates among HIV-positive populations and the medical implications of smoking in this population. This study compared the efficacy of 3 smoking cessation interventions provided in HIV clinical treatment settings. METHODS: Following a baseline assessment, 209 HIV-positive smokers were randomly assigned to 1 of 3 conditions in a parallel group design. Treatment conditions were individual counseling plus nicotine replacement treatment (NRT), a computer-based Internet smoking treatment plus NRT, and self-help plus NRT. Smoking status was determined at follow-up assessments completed at 12, 24, 36, and 52 weeks following treatment initiation. RESULTS: Cessation rates ranged from 15% to 29%; however, no statistically significant differences in abstinence were found among the treatment conditions over time. Those employed, those who reported a greater desire to quit, or those with lower mood disturbance scores were more likely to achieve abstinence (p < .01). The number of cigarettes participants reported smoking in the 24hr prior to each assessment significantly declined over time (p < .001). CONCLUSIONS: Although we found no differences in abstinence rates across groups, the results indicate that integration of smoking cessation interventions is feasible in HIV clinical treatment settings, and cessation results are promising. The overall abstinence rates we report are comparable to those found in similar treatment studies across multiple populations. Further research is warranted.
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Smoking cessation trials targeting people living with HIV who smoke have produced mixed findings.
“Subsequently, smoking cessation trials that target SLWH have yielded mixed findings.7–15”
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- Authors
- Humfleet, G. L., Hall, S. M., Delucchi, K. L., & Dilley, J. W.
- Affiliations
- University of California, San Francisco (US)
- Venue
- Nicotine & Tobacco Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-02-19
- Volume
- 15
- Issue
- 8
- Pages
- 1436-1445
- ISSN
- 1462-2203 (ISSN-L)
- 1469-994X
- PMC
- PMC3715392
- OpenAlex
- W2054136210
- Semantic Scholar
- 7e48536cdfb7f6ee7f4549c62d1379b07731a7f8
- Cited by
- 89
- References
- 59
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 4 · 2023: 3 · 2022: 2 · 2021: 7 · 2020: 4 · 2019: 8 · 2018: 7 · 2017: 4 · 2016: 21 · 2015: 12 · 2014: 10 · 2013: 2
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Nicotine & Tobacco Research (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Tobacco-Related Disease Research Program
- National Institutes of Health (5r01da015791-03)
- National Institute on Drug Abuse (R01DA002538, P50DA009253, DA09253, R01-DA15791)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- smoking cessation, nicotine replacement therapy, individual counseling, self-help, abstinence rates, mood disturbance, desire to quit
- MeSH terms
- Smoking Prevention, Adult, Female, Humans, Male, Middle Aged, HIV Infections, Smoking Cessation
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