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Cited by 34Hepatitis C virus researchLiver Disease Diagnosis and TreatmentLiver physiology and pathology

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Gender and liver fibrosis in chronic hepatitis: the role of iron status

Rigamonti, C., Andorno, S., Maduli, E., Capelli, F., Boldorini, R., Sartori, M.·2005·Alimentary Pharmacology & Therapeutics
DOI 10.1111/j.1365-2036.2005.02517.x
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Abstract

Summary: Background : The role of gender in the progression of fibrosis in chronic hepatitis C is still under investigation. Aim : To investigate whether gender affects the progression of liver disease and/or hides other risk factors. Methods : A prospective series of 121 consecutive patients with chronic hepatitis C underwent liver biopsy. Grading and staging for chronic hepatitis were each evaluated according to Ishak's classification. Results : In univariate and multivariate analysis on the whole group of patients, male gender was not associated either with significant liver fibrosis (Ishak's score >2) or with cirrhosis (Ishak's score >4). On the contrary, in univariate analysis on patients aged ≤50 years, male gender was nearly significantly (P = 0.06) predictive of liver fibrosis, whereas it was not in patients >50 years. Hepatic iron grading, along with age, was an independent factor associated with fibrosis. Moreover, the values of all the variables which describe iron status were significantly higher in males aged ≤50 years in comparison with females of the same age. Conclusions : In chronic hepatitis C, male gender may be predictive of liver fibrosis only in patients aged≤50 years. Among fibrogenetic factors hidden by gender, iron status could play a major role.

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Crossref · 10.1111/j.1365-2036.2005.02517.x

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45 of 45 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 3

  1. Muller R., 1996, The natural history of hepatitis C: clinical experiences, J Hepatol, 24, 52
  2. Searle JW, 1987, Pathology of the Liver
  3. Sartori M, 2001, Gender and liver fibrosis in chronic hepatitis C, Hepatology, 34, 570A

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Metadata

Authors
Rigamonti, C., Andorno, S., Maduli, E., Capelli, F., Boldorini, R., & Sartori, M.
Affiliations
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
Corresponding author
Sartori, M.
ORCID
Venue
Alimentary Pharmacology & Therapeutics
Publisher
Wiley
Published
2005-06
Volume
21
Issue
12
Pages
1445-1451
ISSN
  • 0269-2813 (ISSN-L)
  • 1365-2036
DOI
10.1111/j.1365-2036.2005.02517.x
OpenAlex
W2045385622
Cited by
34
References
45
Citations by year
2025: 1 · 2024: 1 · 2023: 5 · 2022: 1 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 2 · 2014: 1 · 2013: 1 · 2012: 3
FWCI
0.44
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 8 d)
Locations
  • Alimentary Pharmacology & Therapeutics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Hepatology › Hepatitis C virus research
  • Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
  • Health Sciences › Medicine › Hepatology › Liver physiology and pathology
Keywords
chronic hepatitis C, liver fibrosis, gender differences, iron status, liver cirrhosis, Ishak score, fibrosis progression, age as risk factor
MeSH terms
Adult, Aged, Biopsy, Female, Ferritins, Humans, Iron, Liver Cirrhosis, Male, Middle Aged, Prospective Studies, Transferrin, Disease Progression, Hepatitis C, Chronic

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