Antibacterial activity in microalgae cultures
Open accessAbstract
Five cultures of microalgae (Chlorella minutissima, Tetraselmis chui, Nannochloropsis sp., Arthrospira platensis and Isochrysis sp.) with no culturable bacteria were tested for their ability to inhibit the growth of six Vibrio bacterial strains (V. parahaemolyticus, V. anguillarum, V. splendidus, V. scophthalmi, V. alginolyticus and V. lentus). The influence of light on the antibacterial activity of the microalgae was investigated. All microalgae cultures inhibited the growth of bacteria compared with the control treatments (P < 0.05), and their antibacterial activity was not influenced by the presence or absence of light. In the control groups, the numbers of bacteria increased exponentially during the experimental period in the absence of microalgae cells demonstrating that the bacterial cells were able to utilize the growth medium of microalgae cultures. The present results may explain the low levels or absence of Vibrio strains in microalgae cultures, and the positive effect of addition of microalgae in rearing of fish larvae, and implicate the production of antibacterial compounds by microalgae cells.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Arthrospira platensis has been shown to have significant antimicrobial activity against strains of Vibrio parahaemolyticus, Vibrio anguillarum, Vibrio splendidus, Vibrio scophthalmi, Vibrio alginolyticus and Vibrio lentus.
“In addition, the Arthrospira platensis has been shown to have significant antimicrobial activity against strains of Vibrio parahaemolyticus, Vibrio anguillarum, Vibrio splendidus, Vibrio scophthalmi, Vibrio alginolyticus and Vibrio lentus [64].”
From Application of Arthrospira platensis for Medicinal Purposes and the Food Industry: A Review of the Literature (2023) · cites this paper as [64]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669 · see citing works
Baltosser, W. H., & Zar, J. H. (1996) · Ecology · doi:10.2307/2265725 · Cited by 35,166 · see citing works
Guillard, R. R., & Ryther, J. (1962) · Canadian Journal of Microbiology (print) · doi:10.1139/m62-029 · Cited by 7,663 · see citing works
Methods for general and molecular bacteriology
Gerhardt, P. (1994) · Cited by 6,620 · see citing works
Microalgae as sources of pharmaceuticals and other biologically active compounds
Borowitzka, M. A. (1995) · Journal of Applied Phycology · doi:10.1007/bf00003544 · Cited by 520 · see citing works
Defoirdt, T., Boon, N., Sorgeloos, P., Verstraete, W., & Bossier, P. (2007) · Trends in biotechnology · doi:10.1016/j.tibtech.2007.08.001 · Cited by 381 · see citing works
Desbois, A. P., Mearns-Spragg, A., & Smith, V. J. (2008) · Marine Biotechnology · doi:10.1007/s10126-008-9118-5 · Cited by 296 · see citing works
Chlorellin, an Antibacterial Substance from Chlorella
Pratt, R., Daniels, T. C., Eiler, J. J., Gunnison, J. B., Kumler, W. D., Oneto, J. F., Strait, L. A., Spoehr, H. A., Hardin, G., Milner, H. W., et al. (1944) · Science · doi:10.1126/science.99.2574.351 · Cited by 263 · see citing works
Antibacterial activity of volatile component and various extracts of <i>Spirulina platensis</i>
Ozdemir, G., Ulku Karabay, N., Dalay, M. C., & Pazarbasi, B. (2004) · Phytotherapy Research · doi:10.1002/ptr.1541 · Cited by 235 · see citing works
Nutritional effects of algal addition in first-feeding of turbot (Scophthalmus maximus L.) larvae
Reitan, K. I., Rainuzzo, J. R., Øie, G., & Ôlsen, Y. (1993) · Aquaculture · doi:10.1016/0044-8486(93)90461-7 · Cited by 204 · see citing works
Larviculture of marine finfish in Europe
Shields, R. J. (2001) · Aquaculture · doi:10.1016/s0044-8486(01)00694-9 · Cited by 183 · see citing works
Nicolas, J. L., Robic, E., & Ansquer, D. (1989) · Aquaculture · doi:10.1016/0044-8486(89)90036-7 · Cited by 182 · see citing works
Algal addition in sea bass (Dicentrarchus labrax) larvae rearing: effect on digestive enzymes
Cahu, C. L., Zambonino‐Infante, J., Péres, A., Quazuguel, P., & Gall, M. M. L. (1998) · Aquaculture · doi:10.1016/s0044-8486(97)00295-0 · Cited by 170 · see citing works
Superoxide production by marine microalgae
Marshall, J.-A., de Salas, M. F., Oda, T., & Hallegraeff, G. M. (2005) · Marine Biology · doi:10.1007/s00227-005-1596-7 · Cited by 168 · see citing works
Munro, P., Barbour, A., & Blrkbeck, T. H. (1994) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1994.tb04402.x · Cited by 132 · see citing works
Øie, G., Makridis, P., Reitan, K. I., et al. (1997) · Aquaculture · doi:10.1016/s0044-8486(96)01514-1 · Cited by 120 · see citing works
Self-citationVerner–Jeffreys, D. W., Shields, R. J., Bricknell, I. R., & Birkbeck, T. H. (2003) · Aquaculture · doi:10.1016/s0044-8486(02)00348-4 · Cited by 114 · see citing works
Salvesen, I., Skjermo, J., & Vadstein, Ô. (1999) · Aquaculture · doi:10.1016/s0044-8486(99)00110-6 · Cited by 107 · see citing works
THE ANTIBACTERIAL ACTIVITY OF MARINE PLANKTONIC ALGAE
Duff, D. C. B., Bruce, D. L., & Antia, N. J. (1966) · Canadian Journal of Microbiology · doi:10.1139/m66-120 · Cited by 91 · see citing works
Salvesen, I., Reitan, K. I., Skjermo, J., & Øie, G. (2000) · Aquaculture International · doi:10.1023/a:1009200926452 · Cited by 88 · see citing works
Makridis, P., Costa, R. A., & Dinis, M. T. (2006) · Aquaculture · doi:10.1016/j.aquaculture.2005.12.010 · Cited by 81 · see citing works
Self-citationMakridis, P., Fjellheim, A. J., Skjermo, J., & Vadstein, Ô. (2000) · Aquaculture International · doi:10.1023/a:1009251531832 · Cited by 79 · see citing works
Self-citationRoncarati, A., Meluzzi, A., Acciarri, S., Tallarico, N., & Melotti, P. (2004) · Journal of the World Aquaculture Society · doi:10.1111/j.1749-7345.2004.tb00104.x · Cited by 77 · see citing works
Use of PCRRFLP for genotyping 16S rRNA and characterizing bacteria cultured from halibut fry
Jensen, S., Bergh, Ø., Enger, Ø., et al. (2002) · Canadian Journal of Microbiology · doi:10.1139/w02-033 · Cited by 76 · see citing works
Tendencia, E. A., & de la Peña, M. R. (2003) · Aquaculture · doi:10.1016/s0044-8486(02)00524-0 · Cited by 59 · see citing works
Protein depletion of the rotifer Brachionus plicatilis during starvation
Makridis, P., & Ôlsen, Y. (1999) · Aquaculture · doi:10.1016/s0044-8486(99)00020-4 · Cited by 48 · see citing works
Self-citationBioactive Chemicals in Microalgae
Skulberg, O. M. (2003) · Wiley eBooks · doi:10.1002/9780470995280.ch30 · Cited by 43 · see citing works
Cam, D. T. V., Hao, N. V., Dierckens, K. R., et al. (2009) · Aquaculture · doi:10.1016/j.aquaculture.2009.03.009 · Cited by 43 · see citing works
Prol, M. J., Bruhn, J. B., Pintado, J., et al. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2008.04096.x · Cited by 37 · see citing works
Control of Vibrio spp. in Shrimp Hatcheries Using the Green Algae Tetraselmis suecica
Regunathan, C., & Wesley, S. G. (2004) · Asian Fisheries Science · doi:10.33997/j.afs.2004.17.2.006 · Cited by 37 · see citing works
Antibacterial Activity Of Marine Microalgae Against Multidrug Resistant Human Pathogens
Lazarus, S. M., & Bhimba, V. (2008) · International Journal on Applied Bio-Engineering · doi:10.18000/ijabeg.10020 · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Gentscheva, G., Nikolova, K., Panayotova, V., Peycheva, K., Makedonski, L., Slavov, P., Radusheva, P., Petrova, P., & Yotkovska, I. (2023) · Life · doi:10.3390/life13030845 · Cited by 106 · see citing works
- Authors
- Kokou, F., Makridis, P., Kentouri, M., & Divanach, P.
- Affiliations
- Biology Department; University of Crete; Crete; Greece
- Hellenic Centre for Marine Research (GR)
- University of Crete (GR)
- Corresponding author
- Makridis, Pavlos
- Venue
- Aquaculture Research
- Publisher
- Hindawi Limited
- Published
- 2011-09-02
- Volume
- 43
- Issue
- 10
- Pages
- 1520-1527
- ISSN
- 1355-557X (ISSN-L)
- OpenAlex
- W2024084854
- Cited by
- 100
- References
- 31
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 11 · 2023: 11 · 2022: 14 · 2021: 10 · 2020: 5 · 2019: 7 · 2018: 10 · 2017: 4 · 2016: 3 · 2015: 6 · 2014: 6 · 2013: 3 · 2012: 1
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Aquaculture Research (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Vibrio bacteria research studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Keywords
- microalgae, antibacterial activity, Vibrio, Chlorella minutissima, Tetraselmis chui, Nannochloropsis, Spirulina platensis, Isochrysis, light effects, fish larvae rearing, antibacterial agents, bacterial growth inhibition
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
