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Cited by 375

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function

Thompson, Craig B., Eaton, Katherine A., Princiotta, Steven M., Rushin, Carol A., Valeri, C. Robert·1982·British Journal of Haematology
DOI 10.1111/j.1365-2141.1982.tb01947.x
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Abstract

A method for the separation of platelets on the basis of their size has been developed using counterflow centrifugation. Platelets were separated, free of plasma proteins and other cells, into seven subpopulations. The smallest‐sized platelets, designated as Fraction 1, had a mean platelet volume (MPV) of 3.94 ± 0.60 μm 3 (SD). Each successive fraction had a progressively larger MPV. The MPV for the largest‐sized platelets, designated Fraction 7, was 8.19 ± 0.64 μm 3. The MPV for the original platelets prior to fractionation was 6.57 ± 0.61 μm 3. The mean density of Fraction 1 platelets was 1.067 ± 0.002 g/cm 3, while Fraction 7 had a mean density of 1.072 ± 0.001 g/cm 3. Transmission electron microscopy demonstrated that Fraction 1 had 4.3 ± 0.9 dense bodies per platelet, and Fraction 7 had 12.6 ± 2.4 dense bodies per platelet. Platelet LDH activity showed that the Fraction 1 platelets had 4.77 ± 0.92 iu per 10 10 platelets; Fraction 7 platelets had 14.88 ± 1.23 iu per 10 10 platelets. The LDH activity in the platelets before separation into subpopulations was 9.47 ± 1.45 iu per 10 10 platelets.

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Metadata

Authors
Thompson, C. B., Eaton, K. A., Princiotta, S. M., Rushin, C. A., & Valeri, C. R.
Venue
British Journal of Haematology
Publisher
Wiley
Published
1982-03
Volume
50
Issue
3
Pages
509-519
ISSN
  • 0007-1048 (ISSN-L)
  • 1365-2141
DOI
10.1111/j.1365-2141.1982.tb01947.x
OpenAlex
W2048675853
Cited by
375
References
10
FWCI
5.34
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function. https://app.cochat.ai/papers/10.1111/j.1365-2141.1982.tb01947.x
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Thompson, C. B., Eaton, K. A., Princiotta, S. M., Rushin, C. A., & Valeri, C. R. (1982). Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function. British Journal of Haematology. https://doi.org/10.1111/j.1365-2141.1982.tb01947.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.