The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Malignancies and survival patterns in the National Cancer Institute inherited bone marrow failure syndromes cohort study
Open accessAbstract
Summary: Fanconi anaemia (FA), dyskeratosis congenita (DC), Diamond‐Blackfan anaemia (DBA), and Shwachman‐Diamond syndrome (SDS) comprise major inherited bone marrow failure syndromes (IBMFS). Adverse events include severe bone marrow failure (BMF), myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and solid tumours (ST). The natural history of FA is well characterised; hazard rates in the other syndromes have not yet been quantified. An open cohort was established at the National Cancer Institute (NCI) in 2002. Patients enrolled prior to December, 2007 were followed up to December, 2008. Diagnoses were confirmed with standard tests. Age‐associated risks of adverse events were calculated. Most patients in each syndrome survived to young adulthood. Patients with FA had earlier onset of cancers, need for stem cell transplant, and death; followed by DC; DBA and SDS were mildest. While FA and DC patients had markedly increased risks of cancer, AML and MDS, there were no cases of leukaemia in DBA or SDS patients. The NCI cohort provides the first direct quantitative comparison of timing and magnitude of cancer risk in the IBMFS. The findings demonstrate that both FA and DC are major cancer susceptibility syndromes. The IBMFS, historically considered paediatric disorders, have important management implications for physicians treating adult patients.
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Cites
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,181
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
A 20-year perspective on the International Fanconi Anemia Registry (IFAR)
Kutler, D. I., Singh, B., Satagopan, J., Batish, S. D., Berwick, M., Giampietro, P. F., Hanenberg, H., & Auerbach, A. D. (2003) · Blood · doi:10.1182/blood-2002-07-2170 · Cited by 618
Cancer incidence in persons with Fanconi anemia
Rosenberg, P. S., Greene, M. H., & Alter, B. P. (2003) · Blood · doi:10.1182/blood-2002-05-1498 · Cited by 520
Self-citationCancer in dyskeratosis congenita
Alter, B. P., Giri, N., Savage, S. A., & Rosenberg, P. S. (2009) · Blood · doi:10.1182/blood-2008-12-192880 · Cited by 478
Self-citationVlachos, A., Ball, S., Dahl, N., Alter, B. P., Sheth, S., Ramenghi, U., Meerpohl, J., Karlsson, S., Liu, J. M., Leblanc, T., et al. (2008) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07269.x · Cited by 478
Self-citationRosenberg, P. S. (2006) · Blood · doi:10.1182/blood-2005-11-4370 · Cited by 431
Self-citationNathan And Oski's Hematology Of Infancy And Childhood
Saxon, B. (2004) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2004.00352.x · Cited by 421
Savage, S. A., Giri, N., Baerlocher, G. M., Orr, N., Lansdorp, P. M., & Alter, B. P. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.10.004 · Cited by 414
Self-citationHigh Incidence of Head and Neck Squamous Cell Carcinoma in Patients With Fanconi Anemia
Kutler, D. I., Auerbach, A. D., Satagopan, J., Giampietro, P. F., Batish, S. D., Huvos, A. G., Goberdhan, A., Shah, J. P., & Singh, B. (2003) · Archives of Otolaryngology–Head & Neck Surgery · doi:10.1001/archotol.129.1.106 · Cited by 370
Cited by
Fanconi anaemia and cancer: an intricate relationship
Nalepa, G., & Clapp, D. W. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.116 · Cited by 389
Vlachos, A., Rosenberg, P. S., Atsidaftos, E., Alter, B. P., & Lipton, J. M. (2012) · Blood · doi:10.1182/blood-2011-08-375972 · Cited by 309
Self-citationLabi, V, & Erlacher, M. (2015) · Cell Death & Disease · doi:10.1038/cddis.2015.20 · Cited by 295
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
Zhong, F., Savage, S. A., Shkreli, M., Giri, N., Jessop, L., Myers, T., Chen, R., Alter, B. P., & Artandi, S. E. (2011) · Genes & Development · doi:10.1101/gad.2006411 · Cited by 262
Self-citationBatista, L. F. Z., Pech, M. F., Zhong, F. L., Nguyen, H. N., Xie, K. T., Zaug, A. J., Crary, S. M., Choi, J., Sebastiano, V., Cherry, A., et al. (2011) · Nature · doi:10.1038/nature10084 · Cited by 260
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Metadata
- Authors
- Alter, B. P., Giri, N., Savage, S. A., Peters, J. A., Loud, J. T., Leathwood, L., Carr, A. G., Greene, M. H., & Rosenberg, P. S.
- Venue
- British Journal of Haematology
- Publisher
- Wiley
- Published
- 2010-07
- Volume
- 150
- Issue
- 2
- Pages
- 179-188
- ISSN
- 0007-1048 (ISSN-L)
- 1365-2141
- OpenAlex
- W1528119152
- Cited by
- 324
- References
- 28
- FWCI
- 12.57
- Type
- journal article
- Language
- en
- Open access
- green
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- Alter, B. P., Giri, N., Savage, S. A., Peters, J. A., Loud, J. T., Leathwood, L., Carr, A. G., Greene, M. H., & Rosenberg, P. S. (2010). Malignancies and survival patterns in the National Cancer Institute inherited bone marrow failure syndromes cohort study. British Journal of Haematology. https://doi.org/10.1111/j.1365-2141.2010.08212.x
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