The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Expression of insulin pathway genes during the period of caste determination in the honey bee, Apis mellifera
Open accessAbstract
Female honeybees have two castes, queens and workers. Developmental fate is determined by larval diet. Coding sequences made available through the Honey Bee Genome Sequencing Consortium allow for a pathway‐based approach to understanding caste determination. We examined the expression of several genes of the insulin signalling pathway, which is central to regulation of growth based on nutrition. We found one insulin‐like peptide expressed at very high levels in queen but not worker larvae. Also, the gene for an insulin receptor was expressed at higher levels in queen larvae during the 2nd larval instar. These results demonstrate that the insulin pathway is a compelling candidate for pursing the relationship between diet and downstream signals involved in caste determination and differentiation.
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Cites
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Drosophila's Insulin/PI3-Kinase Pathway Coordinates Cellular Metabolism with Nutritional Conditions
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The Role of Nourishment in Oogenesis
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Self-citationGraham, J. M. (1992) · Cited by 248
Mutations in insulin signaling pathway alter juvenile hormone synthesis in Drosophila melanogaster
Tu, M.-P., Yin, C.-M., & Tatar, M. (2005) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2005.02.009 · Cited by 242
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Expression profiles during honeybee caste determination
Evans, J. D., & Wheeler, D. E. (2000) · Genome biology · doi:10.1186/gb-2000-2-1-research0001 · Cited by 199
Self-citationGene expression and the evolution of insect polyphenisms†
Evans, J. D., & Wheeler, D. E. (2000) · BioEssays · Cited by 183
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Cited by
Claudianos, C., Ranson, H., Johnson, R. M., Biswas, S., Schuler, M. A., Berenbaum, M. R., Feyereisen, R., & Oakeshott, J. G. (2006) · Insect Molecular Biology · doi:10.1111/j.1365-2583.2006.00672.x · Cited by 786
Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling
Zheng, H., Powell, J. E., Steele, M. I., Dietrich, C., & Moran, N. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701819114 · Cited by 664
Lourenço, A. P., Mackert, A., dos Santos Cristino, A., & Simões, Z. L. P. (2008) · Apidologie · doi:10.1051/apido:2008015 · Cited by 355
Davidson, D. W. (1998) · Ecological Entomology · doi:10.1046/j.1365-2311.1998.00145.x · Cited by 329
Elango, N., Hunt, B. G., Goodisman, M. A. D., & Yi, S. V. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900301106 · Cited by 326
Metadata
- Authors
- Wheeler, D. E., Buck, N., & Evans, J. D.
- Venue
- Insect Molecular Biology
- Publisher
- Wiley
- Published
- 2006-10
- Volume
- 15
- Issue
- 5
- Pages
- 597-602
- ISSN
- 0962-1075 (ISSN-L)
- 1365-2583
- OpenAlex
- W2101831496
- Cited by
- 709
- References
- 13
- FWCI
- 16.61
- Type
- journal article
- Language
- en
- Open access
- bronze
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