Effect on blood pressure of a continued nursing intervention using chronotherapeutics for adult Chinese hypertensive patients
Abstract
AIMS AND OBJECTIVES: (1) To explore the effect of continued nursing intervention on hypertensive patients based on chronotherapeutics. (2) To identify the factors affecting hypertensive patients' compliance to the chronotherapeutics-oriented nursing interventions. BACKGROUND: Chronotherapy provides a means of individual treatment for hypertension according to the circadian blood-pressure profile of each patient and constitutes a new option in optimising blood-pressure control and reducing risk from hypertension. DESIGN: Experimental study. METHODS: All participants enrolled were randomly divided into the intervention group and the control group and they all took antihypertensive medicine prescribed by their doctors under ambulatory blood pressure monitoring. According to individual ambulatory blood pressure monitoring measures, interventions were implemented. RESULTS: (1) There were significant differences in blood pressure and compliance to chronotherapeutics between the two groups before and after the intervention. (2) Single variant and multiple factors analysis revealed different characteristics influencing chronotherapeutic compliance of hypertensive patients. CONCLUSIONS: Under ambulatory blood pressure monitoring, continued nursing intervention for hypertensive patients guided by chronotherapeutics could effectively improve blood-pressure control and chronotherapeutic compliance. RELEVANCE TO CLINICAL PRACTICE: Health care providers who deal with Chinese hypertensive patients can improve patients' therapeutic compliance and blood pressure control guided by chronotherapeutics. According to different influencing factors on patients' chronotherapeutic compliance nurses should pay more attention to those whose compliance might be worse.
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The goal of medication dosing is to optimize effectiveness without causing serious adverse side effects, both of which may depend on circadian time.
“The goal of medication dosing is to optimize effectiveness without causing serious adverse side effects, both of which may depend on circadian time (170, 171).”
From Role of the circadian system in cardiovascular disease (2018) · cites this paper as [171]
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- Authors
- Zang, X., Liu, J., Chai, Y., Wong, F. K. Y., & Zhao, Y.
- Affiliations
- Shandong University of Traditional Chinese Medicine (CN)
- Corresponding author
- Zhao, Yue
- Venue
- Journal of Clinical Nursing
- Publisher
- Wiley
- Published
- 2010-03-12
- Volume
- 19
- Issue
- 7-8
- Pages
- 1149-1156
- ISSN
- 0962-1067 (ISSN-L)
- 1365-2702
- OpenAlex
- W2103116365
- Cited by
- 8
- References
- 21
- Citations by year
- 2024: 2 · 2018: 2 · 2015: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Nursing (publishedVersion)
- PubMed (publishedVersion)
- PolyU Institutional Research Archive (Hong Kong Polytechnic University) (submittedVersion)
- Funders
- Tianjin University
- Tianjin Medical University
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Keywords
- hypertension, chronotherapy, nursing interventions, blood pressure control, ambulatory blood pressure monitoring, medication adherence, circadian blood pressure rhythm, Chinese hypertensive patients
- MeSH terms
- Adult, Antihypertensive Agents, China, Female, Humans, Hypertension, Male, Patient Compliance, Pilot Projects, Multivariate Analysis, Logistic Models, Blood Pressure Monitoring, Ambulatory, Drug Chronotherapy
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