The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
Dietary fats and coronary heart disease
Abstract
Abstract. Willett WC (Harvard School of Public Health, Boston, MA, USA). Dietary fats and coronary heart disease (Review).J Intern Med 2012;272: 13–24. The relation of dietary fat to risk of coronary heart disease (CHD) has been studied extensively using many approaches, including controlled feeding studies with surrogate end‐points such as plasma lipids, limited randomized trials and large cohort studies. All lines of evidence indicate that specific dietary fatty acids play important roles in the cause and the prevention of CHD, but total fat as a percent of energy is unimportant.Trans fatty acids from partially hydrogenated vegetable oils have clear adverse effects and should be eliminated. Modest reductions in CHD rates by further decreases in saturated fat are possible if saturated fat is replaced by a combination of poly‐ and mono‐unsaturated fat, and the benefits of polyunsaturated fat appear strongest. However, little or no benefit is likely if saturated fat is replaced by carbohydrate, but this will in part depend on the form of carbohydrate. Because both N‐6 and N‐3 polyunsaturated fatty acids are essential and reduce risk of heart disease, the ratio of N‐6 to N‐3 is not useful and can be misleading. In practice, reducing red meat and dairy products in a food supply and increasing intakes of nuts, fish, soy products and nonhydrogenated vegetable oils will improve the mix of fatty acids and have a markedly beneficial effect on rates of CHD.
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Cites
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia
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Diet, lifestyle, and the risk of type 2 diabetes mellitus in women.
Hu, F. B., Manson, J. E., Stampfer, M. J., Colditz, G., Liu, S., Solomon, C. G., & Willett, W. C. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010492 · Cited by 2,901
Self-citationBurr, M. L., Gilbert, J. F., Holliday, R. M., Elwood, P. C., Fehily, A. M., Rogers, S., Sweetnam, P. M., & Deadman, N. M. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90828-3 · Cited by 2,610
The Inverse Relation between Fish Consumption and 20-Year Mortality from Coronary Heart Disease
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Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
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Dietary Fat Intake and the Risk of Coronary Heart Disease in Women
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Self-citationTrans fatty acids and cardiovascular disease
Mozaffarian, D., Katan, M. B., Ascherio, A., Stampfer, M. J., & Willett, W. C. (2006) · New England Journal of Medicine · doi:10.1056/nejmra054035 · Cited by 1,752
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Cited by
Association of Specific Dietary Fats With Total and Cause-Specific Mortality
Wang, D. D., Li, Y., Chiuve, S. E., Stampfer, M. J., Manson, J. E., Rimm, E. B., Willett, W. C., & Hu, F. B. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.2417 · Cited by 439
Self-citationReview: Nutrient density and nutritional value of meat products and non-meat foods high in protein
Bohrer, B. M. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.04.016 · Cited by 317
Laska, M. N., Hearst, M. O., Lust, K., Lytle, L. A., & Story, M. (2015) · Public Health Nutrition · doi:10.1017/s1368980014002717 · Cited by 79
Risk factors for myocardial infarction in very young South Asians
Gupta, M. D., Gupta, P., MP, G., Roy, A., & Qamar, A. (2020) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0000000000000532 · Cited by 27
Metadata
- Authors
- Willett, W. C.
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 2012-06-21
- Volume
- 272
- Issue
- 1
- Pages
- 13-24
- ISSN
- 0954-6820 (ISSN-L)
- 1365-2796
- OpenAlex
- W1575865313
- Cited by
- 297
- References
- 97
- FWCI
- 23.95
- Type
- journal article
- Language
- en
- Open access
- closed
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