The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Evolution of mutation rates in bacteria
Open accessAbstract
Summary: Evolutionary success of bacteria relies on the constant fine‐tuning of their mutation rates, which optimizes their adaptability to constantly changing environmental conditions. When adaptation is limited by the mutation supply rate, under some conditions, natural selection favours increased mutation rates by acting on allelic variation of the genetic systems that control fidelity of DNA replication and repair. Mutator alleles are carried to high frequency through hitchhiking with the adaptive mutations they generate. However, when fitness gain no longer counterbalances the fitness loss due to continuous generation of deleterious mutations, natural selection favours reduction of mutation rates. Selection and counter‐selection of high mutation rates depends on many factors: the number of mutations required for adaptation, the strength of mutator alleles, bacterial population size, competition with other strains, migration, and spatial and temporal environmental heterogeneity. Such modulations of mutation rates may also play a role in the evolution of antibiotic resistance.
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Cites
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High Frequency of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Lung Infection
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Evolution of high mutation rates in experimental populations of E. coli
Sniegowski, P. D., Gerrish, P. J., & Lenski, R. E. (1997) · Nature · doi:10.1038/42701 · Cited by 879
High Mutation Frequencies Among Escherichia coli and Salmonella Pathogens
LeClerc, J. E., Li, B., Payne, W. L., & Cebula, T. A. (1996) · Science · doi:10.1126/science.274.5290.1208 · Cited by 817
Role of mutator alleles in adaptive evolution
Taddei, F., Radman, M., Maynard-Smith, J., Toupance, B., Gouyon, P. H., & Godelle, B. (1997) · Nature · doi:10.1038/42696 · Cited by 677
The population genetics of ecological specialization in evolving Escherichia coli populations
Cooper, V. S., & Lenski, R. E. (2000) · Nature · doi:10.1038/35037572 · Cited by 519 · cited 1×
“For example, an adaptive mutation in one environment can be deleterious in another [a phenomenon called ‘antagonistic pleiotropy’ (Cooper and Lenski, 2000)].”
BackgroundDNA Mismatch Repair: Molecular Mechanisms and Biological Function
Schofield, M. J., & Hsieh, P. (2003) · Annual Review of Microbiology · doi:10.1146/annurev.micro.57.030502.090847 · Cited by 492
Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse Gut
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Self-citationMulvey, M. A., Schilling, J. D., Martinez, J. J., & Hultgren, S. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.16.8829 · Cited by 468
Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori
Björkholm, B., Sjölund, M., Falk, P. G., Berg, O. G., Engstrand, L., & Andersson, D. I. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241517298 · Cited by 404
Cited by
Genetic drift, selection and the evolution of the mutation rate
Lynch, M., Ackerman, M. S., Gout, J.-F., Long, H., Sung, W., Thomas, W. K., & Foster, P. L. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.104 · Cited by 911
Diversity within Species: Interpreting Strains in Microbiomes
Van Rossum, T., Ferretti, P., Maistrenko, O. M., & Bork, P. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0368-1 · Cited by 441
Groussin, M., & Gouy, M. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr098 · Cited by 119
Boyce, K. J., Wang, Y., Verma, S., Shakya, V. P. S., Xue, C., & Idnurm, A. (2017) · mBio · doi:10.1128/mbio.00595-17 · Cited by 101
Deng, Y., & Fong, S. S. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.239616 · Cited by 33
Metadata
- Authors
- Denamur, E., & Matic, I.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2006-04-21
- Volume
- 60
- Issue
- 4
- Pages
- 820-827
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2102306849
- Cited by
- 401
- References
- 47
- FWCI
- 7.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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