The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Lipid domains in bacterial membranes
Abstract
Summary: The recent development of specific probes for lipid molecules has led to the discovery of lipid domains in bacterial membranes, that is, of membrane areas differing in lipid composition. A view of the membrane as a patchwork is replacing the assumption of lipid homogeneity inherent in the fluid mosaic model of Singer and Nicolson (Science 1972, 175: 720–731). If thus membranes have complex lipid structure, questions arise about how it is generated and maintained, and what its function might be. How do lipid domains relate to the functionally distinct regions in bacterial cells as they are identified by protein localization techniques? This review assesses the current knowledge on the existence of cardiolipin (CL) and phosphatidylethanolamine (PE) domains in bacterial cell membranes and on the specific cellular localization of certain membrane proteins, which include phospholipid synthases, and discusses possible mechanisms, both chemical and physiological, for the formation of the lipid domains. We propose that bacterial membranes contain a mosaic of microdomains of CL and PE, which are to a significant extent self‐assembled according to their respective intrinsic chemical characteristics. We extend the discussion to the possible relevance of the domains to specific cellular processes, including cell division and sporulation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Singer, S. J., & Nicolson, G. L. (1972) · Science · doi:10.1126/science.175.4023.720 · Cited by 9,154
Lipid polymorphism and the functional roles of lipids in biological membranes
Cullis, P. R., & De Kruijff, B. (1979) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(79)90012-1 · Cited by 1,864
MOLECULAR BASIS FOR MEMBRANE PHOSPHOLIPID DIVERSITY: Why Are There So Many Lipids?
Dowhan, W. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.199 · Cited by 1,006
Membranes are more mosaic than fluid
Engelman, D. M. (2005) · Nature · doi:10.1038/nature04394 · Cited by 924
Preferred conformation and molecular packing of phosphatidylethanolamine and phosphatidylcholine
Hauser, H., Pascher, I., Pearson, R. H., & Sundell, S. (1981) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(81)90007-1 · Cited by 888
Lipid intermolecular hydrogen bonding: influence on structural organization and membrane function
Boggs, J. M. (1987) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(87)90017-7 · Cited by 742
London, E., & Brown, D. A. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0304-4157(00)00007-1 · Cited by 688
Dynamic, yet structured: The cell membrane three decades after the Singer–Nicolson model
Vereb, G., Szöllősi, J., Matkó, J., Nagy, P., Farkas, T., Vígh, L., Mátyus, L., Waldmann, T. A., & Damjanovich, S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1332550100 · Cited by 519
Tethering the Z ring to the membrane through a conserved membrane targeting sequence in FtsA
Pichoff, S., & Lutkenhaus, J. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04522.x · Cited by 439
Mileykovskaya, E., & Dowhan, W. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.4.1172-1175.2000 · Cited by 432
Cited by
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)
Theillet, F.-X., Binolfi, A., Frembgen-Kesner, T., Hingorani, K., Sarkar, M., Kyne, C., Li, C., Crowley, P. B., Gierasch, L., Pielak, G. J., et al. (2014) · Chemical Reviews · doi:10.1021/cr400695p · Cited by 503
Antimicrobial Peptides Targeting Gram-Positive Bacteria
Malanovic, N., & Lohner, K. (2016) · Pharmaceuticals · doi:10.3390/ph9030059 · Cited by 420
Functional microdomains in bacterial membranes
López, D., & Kolter, R. (2010) · Genes & Development · doi:10.1101/gad.1945010 · Cited by 346
Osman, C., Haag, M., Potting, C., Rodenfels, J., Dip, P. V., Wieland, F. T., Brügger, B., Westermann, B., & Langer, T. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200810189 · Cited by 299
Cardiolipin binding in bacterial respiratory complexes: Structural and functional implications
Arias-Cartin, R., Grimaldi, S., Arnoux, P., Guigliarelli, B., & Magalon, A. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.04.005 · Cited by 117
Metadata
- Authors
- Matsumoto, K., Kusaka, J., Nishibori, A., & Hara, H.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2006-08
- Volume
- 61
- Issue
- 5
- Pages
- 1110-1117
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W1973044434
- Cited by
- 289
- References
- 40
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Lipid domains in bacterial membranes. https://app.cochat.ai/papers/10.1111/j.1365-2958.2006.05317.x
- The paper
- Matsumoto, K., Kusaka, J., Nishibori, A., & Hara, H. (2006). Lipid domains in bacterial membranes. Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.2006.05317.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
