The DOI matches its Crossref record.
Opioids and the gut: pharmacology and current clinical experience
Abstract
Abstract This article reviews the pharmacology and physiology of opiate receptors and the current and potential uses of opioid agonists and antagonists in clinical gastroenterology. μ‐receptors are involved in motor and sensory functions, and their modulation is established for treatment of diarrhea. μ‐antagonists have potential to reverse endogenous (e.g., postoperative ileus) or iatrogenic dysmotility (e.g., opioid bowel dysfunction). Modulation of the function of κ‐receptors may be a novel approach to control visceral pain in functional gut disorders. Results of formal testing of novel opioid modulators are keenly awaited.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Meissner, W., Leyendecker, P., Mueller‐Lissner, S., Nadstawek, J., Hopp, M., Ruckes, C., Wirz, S., Fleischer, W., & Reimer, K. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2008.06.012 · Cited by 257
Bharucha, A. E., Kudva, Y. C., & Prichard, D. O. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00161 · Cited by 252
Lee, K., Vuong, H. E., Nusbaum, D. J., Hsiao, E. Y., Evans, C. J., & Taylor, A. M. W. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0211-9 · Cited by 172
Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea
Cash, B. D., Lacy, B. E., Schoenfeld, P. S., Dove, L. S., & Covington, P. S. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2016.542 · Cited by 88
The Impact of Opioid Treatment on Regional Gastrointestinal Transit
Poulsen, J. L., Nilsson, M., Brock, C., Sandberg, T. H., Krogh, K., & Drewes, A. M. (2016) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm15175 · Cited by 53
Metadata
- Authors
- De Schepper, H. U., Cremonini, F., Park, M. ‐., & Camilleri, M.
- Venue
- Neurogastroenterology & Motility
- Publisher
- Wiley
- Published
- 2004-04-08
- Volume
- 16
- Issue
- 4
- Pages
- 383-394
- ISSN
- 1350-1925 (ISSN-L)
- 1365-2982
- OpenAlex
- W2040832386
- Cited by
- 214
- References
- 0
- FWCI
- 4.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Opioids and the gut: pharmacology and current clinical experience. https://app.cochat.ai/papers/10.1111/j.1365-2982.2004.00513.x
- The paper
- De Schepper, H. U., Cremonini, F., Park, M. ‐., & Camilleri, M. (2004). Opioids and the gut: pharmacology and current clinical experience. Neurogastroenterology & Motility. https://doi.org/10.1111/j.1365-2982.2004.00513.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
