The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
WRKY70 modulates the selection of signaling pathways in plant defense
Abstract
Summary: Cross‐talk between signal transduction pathways is a central feature of the tightly regulated plant defense signaling network. The potential synergism or antagonism between defense pathways is determined by recognition of the type of pathogen or pathogen‐derived elicitor. Our studies have identified WRKY70 as a node of convergence for integrating salicylic acid (SA)‐ and jasmonic acid (JA)‐mediated signaling events during plant response to bacterial pathogens. Here, we challenged transgenic plants altered in WRKY70 expression as well as WRKY70 knockout mutants of Arabidopsis with the fungal pathogens Alternaria brassicicola and Erysiphe cichoracearum to elucidate the role of WRKY70 in modulating the balance between distinct defense responses. Gain or loss of WRKY70 function causes opposite effects on JA‐mediated resistance to A. brassicicola and the SA‐mediated resistance to E. cichoracearum . While the up‐regulation of WRKY70 caused enhanced resistance to E. cichoracearum , it compromised plant resistance to A. brassicicola . Conversely, down‐regulation or insertional inactivation of WRKY70 impaired plant resistance to E. cichoracearum . Over‐expression of WRKY70 resulted in the suppression of several JA responses including expression of a subset of JA‐ and A. brassicicola ‐responsive genes. We show that this WRKY70 ‐controlled suppression of JA‐signaling is partly executed by NPR1. The results indicate that WRKY70 has a pivotal role in determining the balance between SA‐dependent and JA‐dependent defense pathways.
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Cited by
Salicylic acid, a multifaceted hormone to combat disease
Vlot, A. C., Dempsey, D. A., & Klessig, D. F. (2009) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.050908.135202 · Cited by 2,568
The interaction of plant biotic and abiotic stresses: from genes to the field
Atkinson, N. J., & Urwin, P. E. (2012) · Journal of Experimental Botany · doi:10.1093/jxb/ers100 · Cited by 1,880
Systemic Acquired Resistance: Turning Local Infection into Global Defense
Fu, Z. Q., & Dong, X. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105606 · Cited by 1,524
Arabidopsis WRKY33 transcription factor is required for resistance to necrotrophic fungal pathogens
Zheng, Z., Qamar, S. A., Chen, Z., & Mengiste, T. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2006.02901.x · Cited by 988
Wang, D., Amornsiripanitch, N., & Dong, X. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020123 · Cited by 774
Metadata
- Authors
- Li, J., Brader, G., Kariola, T., & Tapio Palva, E.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2006-04-03
- Volume
- 46
- Issue
- 3
- Pages
- 477-491
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W2166872117
- Cited by
- 565
- References
- 59
- FWCI
- 31.37
- Type
- journal article
- Language
- en
- Open access
- closed
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