The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Cardiovascular disease and hypertension among adults with bipolar I disorder in the United States
Open accessAbstract
OBJECTIVE: Despite ample evidence of excess cardiovascular mortality in bipolar disorder (BD), few studies have demonstrated increased prevalence of cardiovascular disease (CVD) and/or hypertension (HTN) in BD. We therefore examined this topic in a representative epidemiologic sample. METHOD: The 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions was used to determine whether prevalence of physician-diagnosed CVD and HTN is elevated among subjects with lifetime bipolar I disorder (BD-I), and whether CVD and HTN are prevalent at earlier ages among subjects with BD-I. RESULTS: The age-, race-, and sex-adjusted prevalence of CVD was significantly greater among subjects with BD-I versus controls [odds ratio (OR) = 4.95, 95% confidence interval (CI): 4.27-5.75] and versus subjects with major depressive disorder [(MDD); OR =1.80, 95% CI: 1.52-2.14], as was the prevalence of HTN (OR = 2.38, 95% CI: 2.16-2.62 versus controls, OR = 1.44, 95% CI: 1.30-1.61 versus MDD; p < 0.0001 for all). Controlling additionally for marital status, education, income, obesity, smoking, anxiety disorders, and substance use disorders did not substantially alter these findings. The mean age of BD-I subjects with CVD and HTN was 14 and 13 years younger, respectively, than controls with CVD and HTN. CONCLUSIONS: Adults with BD-I are at increased risk of CVD and HTN, prevalent over a decade earlier than non-BD adults. Strategies are needed to prevent excessive and premature cardiovascular burden in BD-I.
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“CVD develops more than a decade earlier in patients with bipolar disorders than in controls.443”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [443]
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Excess Mortality in Bipolar and Unipolar Disorder in Sweden
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“The AUDADIS-IV diagnoses of SUD and of mood and anxiety disorders have demonstrated adequate reliability and validity (17, 26, 27).”
MethodBurden of general medical conditions among individuals with bipolar disorder
Kilbourne, A. M., Cornelius, J. R., Han, X., Pincus, H. A., Shad, M. U., Salloum, I. M., Conigliaro, J. C., & Haas, G. L. (2004) · Bipolar Disorders · doi:10.1111/j.1399-5618.2004.00138.x · Cited by 423
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2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.018 · Cited by 1,582
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ESC/EAS Guidelines for the management of dyslipidaemias
Catapano, A. L., Reiner, Ž., De Backer, G., Graham, I., Taskinen, M.-R., Wiklund, O., Agewall, S., Alegria, E., Chapman, M. J., Durrington, P., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.06.028 · Cited by 706
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Metadata
- Authors
- Goldstein, B. I., Fagiolini, A., Houck, P., & Kupfer, D. J.
- Affiliations
- Sunnybrook Health Science Centre (CA)
- University of Siena (IT)
- University of Pittsburgh (US)
- Corresponding author
- Goldstein, Benjamin I
- Venue
- Bipolar Disorders
- Publisher
- Wiley
- Published
- 2009-08-10
- Volume
- 11
- Issue
- 6
- Pages
- 657-662
- ISSN
- 1398-5647 (ISSN-L)
- 1399-5618
- PMC
- PMC3401900
- OpenAlex
- W1977370435
- Cited by
- 259
- References
- 35
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 8 · 2023: 8 · 2022: 13 · 2021: 13 · 2020: 22 · 2019: 10 · 2018: 19 · 2017: 17 · 2016: 24 · 2015: 30 · 2014: 20 · 2013: 20 · 2012: 17
- FWCI
- 8.84
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Bipolar Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Use Siena air (University of Siena) (submittedVersion)
- Funders
- U.S. Department of Veterans Affairs
- National Institute of Mental Health (R25MH060473)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- bipolar I disorder, cardiovascular disease, hypertension, prevalence, cardiovascular risk, major depressive disorder, comorbidities, NESARC
- MeSH terms
- Adult, Age Factors, Bipolar Disorder, Cardiovascular Diseases, Female, Humans, Hypertension, Male, Middle Aged, Psychiatric Status Rating Scales, Retrospective Studies, United States, Prevalence, Confidence Intervals, Odds Ratio
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