The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Interaction of DNA with Bifunctional Aldehydes
Open accessAbstract
The bifunctional aldehydes glyoxal and malondialdehyde, known to be toxic products of the radiolysis of sugar and other food constituents, interact with DNA in vitro and in vivo as demonstrated by thermal denaturation profiles, chromatographic behavior, and incomplete degradation of the reaction product by deoxyribonuclease. After irradiation of DNA in diluted radioactive glucose solution followed by incubation at slightly acid pH, the radioactivity is found in the core of the enzymic digest only. Attempts to locate the binding site proved that the radiolytic compound is associated preferentially with the guanine and cytidine moiety of the DNA core.
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Citations
Cites
Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090
Cited by
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672
Chemistry of free radical and singlet oxidation of lipids
Frankel, E. N. (1984) · Progress in Lipid Research · doi:10.1016/0163-7827(84)90011-0 · Cited by 462
Interaction of lipid peroxidation products with DNA. A review
Vaca, C. E., Wilhelm, J., & Harms-Ringdahl, M. (1988) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(88)90022-x · Cited by 448
Possible mutagens derived from lipids and lipid precursors
Esterbauer, H., Eckl, P., & Ortner, A. (1990) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(90)90014-3 · Cited by 355
Lipid Peroxidation and Mechanisms of Toxicity
Horton, A. A., Fairhurst, S., & Bus, J. S. (1987) · CRC Critical Reviews in Toxicology · doi:10.3109/10408448709089856 · Cited by 339
Metadata
- Authors
- Brooks, B. R., & Klamerth, O. L.
- Venue
- European Journal of Biochemistry
- Publisher
- Wiley
- Published
- 1968-07
- Volume
- 5
- Issue
- 2
- Pages
- 178-182
- ISSN
- 0014-2956 (ISSN-L)
- 1432-1033
- OpenAlex
- W1976075200
- Cited by
- 167
- References
- 1
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Brooks, B. R., & Klamerth, O. L. (1968). Interaction of DNA with Bifunctional Aldehydes. European Journal of Biochemistry. https://doi.org/10.1111/j.1432-1033.1968.tb00355.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
