Bacterial nitrite-reducing enzymes
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The enzymic reduction of nitrite takes place in a wide range of bacteria and is found to occur in denitrifying, assimilatory and dissimilatory pathways. In this review we describe the major molecular characteristics of the various enzymes employed in each of these processes.
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Nitrate reduction is classified into three major pathways: respiratory denitrification, dissimilatory nitrate reduction to ammonia (DNRA), and assimilatory nitrate reduction.
“Broadly, nitrate reduction is classified into three major pathways (Figure 3)[77,195–197]: 1) Respiratory denitrification, catalyzed by membrane-bound nitrate reductase, nar, or periplasmic nap, is the major electrochemical respiratory pathway for bacterial energy generation under hypoxia via generation of a proton motive force, serving as a two-electron sink in the final step of ATP generation”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [196]
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- Authors
- BRITTAIN, T., BLACKMORE, R., GREENWOOD, C., & THOMSON, A. J.
- Affiliations
- University of Auckland (NZ)
- University of East Anglia (GB)
- Corresponding author
- BRITTAIN, Thomas
- ORCID
- THOMSON, Andrew J.
- Venue
- European Journal of Biochemistry
- Publisher
- Wiley
- Published
- 1992-11
- Volume
- 209
- Issue
- 3
- Pages
- 793-802
- ISSN
- 0014-2956 (ISSN-L)
- 1432-1033
- OpenAlex
- W2059324713
- Cited by
- 105
- References
- 142
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 3 · 2018: 2 · 2016: 2 · 2015: 1 · 2014: 3 · 2013: 2 · 2012: 2
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Journal of Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Pollution › Wastewater Treatment and Nitrogen Removal
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Metalloenzymes and iron-sulfur proteins
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial metabolism and enzyme function
- Keywords
- nitrite reduction, denitrification, bacterial enzymes
- MeSH terms
- Bacteria, Nitrites, Oxidation-Reduction
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