Review article: Importance of the kidney proximal tubular cells in thiazolidinedione-mediated sodium and water uptake

Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption

Guan, Y., Hao, C., Cha, D. R., Rao, R., Lu, W., Kohan, D. E., Magnuson, M. A., Redha, R., Zhang, Y., & Breyer, M. D. (2005) · Nature Medicine · doi:10.1038/nm1278 · Cited by 608 · see citing works

Thiazolidinedione Use, Fluid Retention, and Congestive Heart Failure

Nesto, R. W., Bell, D. S. H., Bonow, R. O., Fonseca, V. A., Grundy, S. M., Horton, E. S., Winter, M. L., Porte, D., Semenkovich, C. F., Smith, S. E., et al. (2004) · Diabetes Care · doi:10.2337/diacare.27.1.256 · Cited by 585 · see citing works

Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels

Ma, T., Yang, B., Gillespie, A.-M., Carlson, E. J., Epstein, C. J., & Verkman, A. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.8.4296 · Cited by 561 · see citing works

CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.

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Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice

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Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

KOBAYASHI, T., DEAK, M., MORRICE, N., & COHEN, P. (1999) · Biochemical Journal · doi:10.1042/bj3440189 · Cited by 405 · see citing works

Cloning and Functional Expression of a New Water Channel Abundantly Expressed in the Testis Permeable to Water, Glycerol, and Urea

Ishibashi, K., Kuwahara, M., Gu, Y., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.33.20782 · Cited by 384 · see citing works

Collecting duct-specific deletion of peroxisome proliferator-activated receptor γ blocks thiazolidinedione-induced fluid retention

Zhang, H., Zhang, A., Kohan, D. E., Nelson, R. D., Gonzalez, F. J., & Yang, T. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501744102 · Cited by 316 · see citing works

Localization of the CHIP28 water channel in rat kidney

Sabolić, I., Valenti, G., Verbavatz, J., et al. (1992) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1992.263.6.c1225 · Cited by 287 · see citing works

Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy

Lang, F. J. W., Klingel, K., Wagner, C. A., Stegen, C. F., Wärntges, S., Friedrich, B., Lanzendörfer, M., Melzig, J., Moschén, I., Steuer, S., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.14.8157 · Cited by 228 · see citing works

Stimulation of Proximal Tubular Cell Apoptosis by Albumin-Bound Fatty Acids Mediated by Peroxisome Proliferator Activated Receptor-γ

Arıcı, M., Chana, R. S., Lewington, A. J. P., et al. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000042167.66685.ea · Cited by 142 · see citing works

Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28.

Zhang, R., Skach, W. R., Hasegawa, H., et al. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.120.2.359 · Cited by 140 · see citing works

Rosiglitazone Activates Renal Sodium- and Water-Reabsorptive Pathways and Lowers Blood Pressure in Normal Rats

Song, J., Knepper, M. A., Hu, X., et al. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.058008 · Cited by 129 · see citing works

Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice

Sohara, E., Rai, T., Miyazaki, J., et al. (2005) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00133.2005 · Cited by 119 · see citing works

Enhancement of the Aquaporin Adipose Gene Expression by a Peroxisome Proliferator-activated Receptor γ

Kishida, K., Shimomura, I., Nishizawa, H., Maeda, N., Kuriyama, H., Kondo, H., Matsuda, M., Nagaretani, H., Ouchi, N., Hotta, K., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m108213200 · Cited by 113 · see citing works

PPARγ activation enhances cell surface ENaCα via up‐regulation of SGK1 in human collecting duct cells

Hong, G., Lockhart, A., Davis, B., Rahmoune, H., Baker, S. F., Liang, Y. S., Thompson, P., Shou, Y., O’Shaughnessy, K. M., Ronco, P. M., et al. (2003) · The FASEB Journal · doi:10.1096/fj.03-0181fje · Cited by 110 · see citing works

Proteomics and the Kidney

Knepper, M. A. (2002) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000014782.37591.c7 · Cited by 109 · see citing works

Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts

Zafiriou, S., Stanners, S. R., Saad, S., Polhill, T. S., Poronnik, P., & Pollock, C. A. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004040278 · Cited by 107 · see citing works

Thiazolidinediones and the risk of edema: A meta-analysis

Berlie, H. D., Kalus, J. S., & Jaber, L. A. (2006) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2006.09.010 · Cited by 99 · see citing works

Effects of the Peroxisomal Proliferator-Activated Receptor-γ Agonist Pioglitazone on Renal and Hormonal Responses to Salt in Healthy Men

Zanchi, A., Chioléro, A., Maillard, M. P., Nussberger, J., Brunner, H., & Burnier, M. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031526 · Cited by 97 · see citing works

Lessons on Renal Physiology from Transgenic Mice Lacking Aquaporin Water Channels

Verkman, A. S. (1999) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1051126 · Cited by 90 · see citing works

PPARγ agonists exert antifibrotic effects in renal tubular cells exposed to high glucose

Panchapakesan, U., Sumual, S., Pollock, C. A., & Chen, X. (2005) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00097.2005 · Cited by 89 · see citing works

High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule

Saad, S., Stevens, V. A., Wassef, L., Poronnik, P., Kelly, D. J., Gilbert, R. E., & Pollock, C. A. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00492.x · Cited by 83 · see citing works

The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel α,β,γ-ENaC

Friedrich, B., Feng, Y., Cohen, P., Risler, T., Vandewalle, A., Bröer, S., Wang, J., Pearce, D., & Lang, F. J. W. (2003) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-002-0993-8 · Cited by 81 · see citing works

The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo

Miyata, K., McCaw, S. E., Marcus, S. L., Rachubinski, R. A., & Capone, J. P. (1994) · Gene · doi:10.1016/0378-1119(94)90707-2 · Cited by 81 · see citing works

GI262570, a Peroxisome Proliferator-Activated Receptor γ Agonist, Changes Electrolytes and Water Reabsorption from the Distal Nephron in Rats

Chen, L., Yang, B., McNulty, J. A., Clifton, L. G., Binz, J. G., Grimes, A. M., Strum, J. C., Harrington, W. W., Chen, Z., Balon, T. W., et al. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.074088 · Cited by 75 · see citing works

The effect of high glucose and PPAR-γ agonists on PPAR-γ expression and function in HK-2 cells

Panchapakesan, U., Pollock, C. A., & Chen, X. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00445.2003 · Cited by 74 · see citing works

Hypotonic induction of SGK1 and Na⁺transport in A6 cells

Rozansky, D. J., Wang, J., Doan, N., Purdy, T., Faulk, T., Bhargava, A., Dawson, K., & Pearce, D. (2002) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00176.2001 · Cited by 65 · see citing works

Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses

Zafiriou, S., Stanners, S. R., Polhill, T. S., et al. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00574.x · Cited by 63 · see citing works

Role of SGK in mineralocorticoid-regulated sodium transport

Pearce, D., Verrey, F., Chen, S.-Y., Mastroberardino, L., Meijer, O. C., Wang, J., & Bhargava, A. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00963.x · Cited by 57 · see citing works

Differential effects of peroxisome proliferator activated receptor-γ (PPARγ) ligands in proximal tubular cells: Thiazolidinediones are partial PPARγ agonists

Chana, R. S., Lewington, A. J. P., & Brunskill, N. J. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00624.x · Cited by 54 · see citing works

PPARγ agonists do not directly enhance basal or insulin-stimulated Na+ transport via the epithelial Na+ channel

Nofziger, C., Chen, L., Shane, M. A., Smith, C. D., Brown, K. K., & Blazer‐Yost, B. L. (2005) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-005-1477-4 · Cited by 54 · see citing works

The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells.

Saad, S., Agapiou, D., Chen, X.-M., Stevens, V. A., & Pollock, C. (2008) · Nephrology, Dialysis and Transplantation · doi:10.1093/ndt/gfn614 · Cited by 51 · see citing works

Edema and Congestive Heart Failure from Thiazolidone Insulin Sensitizers—Excess Sodium Reabsoption in the Collecting Duct

Zhang, H., Zhang, A., Kohan, D. E., Nelson, R. D., Gonzales, F., & Yang, T. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005090935 · Cited by 50 · see citing works

Mechanisms of Regulation of Epithelial Sodium Channel by SGK1 in A6 Cells

de la Rosa, D. Á., Păunescu, T. G., Els, W. J., Helman, S. I., & Canessa, C. M. (2004) · The Journal of General Physiology · doi:10.1085/jgp.200409120 · Cited by 48 · see citing works

Drug Insight: thiazolidinediones and diabetic nephropathy—relevance to renoprotection

Panchapakesan, U., Chen, X., & Pollock, C. A. (2005) · Nature Reviews Nephrology · doi:10.1038/ncpneph0029 · Cited by 43 · see citing works

Physiological roles of AQP7 in the kidney: Lessons from AQP7 knockout mice

Sohara, E., Rai, T., Sasaki, S., et al. (2006) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2006.04.002 · Cited by 42 · see citing works

The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells

Stevens, V., Saad, S., Poronnik, P., et al. (2008) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfm923 · Cited by 39 · see citing works

Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARγ agonist pioglitazone

Artunç, F., Sandulache, D., Nasir, O., Boini, K. M., Friedrich, B., Beier, N., Dicks, E., Pötzsch, S., Klingel, K., Amann, K., et al. (2008) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-007-0401-5 · Cited by 30 · see citing works

Troglitazone Stimulates Basolateral Rheogenic Na+/HCO–3 Cotransport Activity in Rabbit Proximal Straight Tubules

Muto, S., Miyata, Y., Imai, M., et al. (2001) · Nephron Experimental Nephrology · doi:10.1159/000052611 · Cited by 20 · see citing works

Epicardial Adipose Tissue May Mediate Deleterious Effects of Obesity and Inflammation on the Myocardium

Packer, M. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.03.509 · Cited by 656 · see citing works

Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes

Salvatore, T., Galiero, R., Caturano, A., Vetrano, E., Rinaldi, L., Coviello, F., Di Martino, A., Albanese, G., Colantuoni, S., Medicamento, G., et al. (2022) · Biomolecules · doi:10.3390/biom12020176 · Cited by 62 · see citing works

The comparison study of pioglitazone and rosiglitazone on type 2 diabetes with hyperlipemia

Xiang-ji, X. (2009) · Sichuan Medical Journal

Cardiovascular safety of rosiglitazone and pioglitazone

Lu, Y., & Ma, D. (2015) · 药物不良反应杂志 · doi:10.3760/cma.j.issn.1008-5734.2015.02.019

Clinical trials with thiazolidinediones in subjects with Type 2 diabetes – is pioglitazone any different from rosiglitazone?

Doggrell, S. A. (2008) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.9.3.405 · Cited by 29 · see citing works

Rosiglitazone and Pioglitazone for the Treatment of Alzheimer's Disease

Miller, B. W., Willett, K. C., & Desilets, A. R. (2011) · Annals of Pharmacotherapy · doi:10.1345/aph.1q238 · Cited by 128 · see citing works

Dyslipidaemia in Type 2 diabetes: effects of the thiazolidinediones pioglitazone and rosiglitazone

Mukhtar, R., & Reckless, J. (2005) · Diabetic Medicine · doi:10.1111/j.1466-5468.2005.01711c.x · Cited by 8 · see citing works