Toll‐like receptors and pregnancy: Trophoblast as modulators of the immune response

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631 · see citing works

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491 · see citing works

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137 · see citing works

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129 · see citing works

The Danger Model: A Renewed Sense of Self

Matzinger, P. (2002) · Science · doi:10.1126/science.1071059 · Cited by 4,205 · see citing works

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., & Bauer, S. (2004) · Science · doi:10.1126/science.1093620 · Cited by 3,947 · see citing works

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444 · see citing works

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H., Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K., et al. (2003) · Science · doi:10.1126/science.1087262 · Cited by 3,244 · see citing works

Intrauterine infection and preterm delivery

Goldenberg, R. L., Hauth, J. C., & Andrews, W. W. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005183422007 · Cited by 2,548 · see citing works

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., & Kirschning, C. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17406 · Cited by 1,704 · see citing works

Decidual NK cells regulate key developmental processes at the human fetal-maternal interface

Hanna, J. H., Goldman‐Wohl, D., Hamani, Y., Avraham, I., Greenfield, C., Natanson‐Yaron, S., Prus, D., Cohen‐Daniel, L., Arnon, T. I., Manaster, I., et al. (2006) · Nature Medicine · doi:10.1038/nm1452 · Cited by 1,690 · see citing works

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein

Park, J. S., Svetkauskaite, D., He, Q., Kim, J., Strassheim, D., Ishizaka, A., & Abraham, E. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306793200 · Cited by 1,560 · see citing works

Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2

Aliprantis, A. O., Yang, R., Mark, M. R., Suggett, S., Devaux, B., Radolf, J. D., Klimpel, G. R., Godowski, P. J., & Zychlinsky, A. (1999) · Science · doi:10.1126/science.285.5428.736 · Cited by 1,463 · see citing works

Natural killer cells and pregnancy

Moffett-King, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri886 · Cited by 1,235 · see citing works

Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells

Lund, J. M., Sato, A., Akira, S., Medzhitov, R. M., & Iwasaki, A. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030162 · Cited by 1,197 · see citing works

Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to Staphylococcus aureus Infection1

Takeuchi, O., Hoshino, K., & Akira, S. (2000) · Journal of Immunology · doi:10.4049/jimmunol.165.10.5392 · Cited by 1,156 · see citing works

Pattern Recognition Receptors

Gordon, S. (2002) · Cell · doi:10.1016/s0092-8674(02)01201-1 · Cited by 1,153 · see citing works

TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

Yarovinsky, F., Zhang, D., Andersen, J. F., Bannenberg, G. L., Serhan, C. N., Hayden, M. S., Hieny, S. E., Sutterwala, F. S., Flavell, R. A., Ghosh, S., et al. (2005) · Science · doi:10.1126/science.1109893 · Cited by 1,049 · see citing works

Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring

Shi, L., Fatemi, S. H., Sidwell, R. W., & Patterson, P. H. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-01-00297.2003 · Cited by 1,025 · see citing works

A Toll-like Receptor That Prevents Infection by Uropathogenic Bacteria

Zhang, D., Zhang, G., Hayden, M. S., Greenblatt, M. B., Bussey, C., Flavell, R. A., & Ghosh, S. (2004) · Science · doi:10.1126/science.1094351 · Cited by 1,002 · see citing works

The Role of Inflammation and Infection in Preterm Birth

Romero, R. J., Espinoza, J., Gonçalves, L. F., Kusanovic, J. P., Friel, L. A., & Hassan, S. S. (2007) · Seminars in Reproductive Medicine · doi:10.1055/s-2006-956773 · Cited by 913 · see citing works

Negative Regulation of Toll-like Receptor-mediated Signaling by Tollip

Zhang, G., & Ghosh, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109537200 · Cited by 598 · see citing works

Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2

Luther, K., Torosantucci, A., Brakhage, A. A., Heesemann, J., & Ebel, F. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00796.x · Cited by 582 · see citing works

The apoptotic signaling pathway activated by Toll‐like receptor‐2

Aliprantis, A. O., Yang, R., Weiss, D. S., Godowski, P., & Zychlinsky, A. (2000) · The EMBO Journal · doi:10.1093/emboj/19.13.3325 · Cited by 502 · see citing works

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

Lotz, M., Gütle, D., Walther, S., Ménard, S., Bogdan, C., & Hornef, M. W. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050625 · Cited by 464 · see citing works

Membrane Sorting of Toll-like Receptor (TLR)-2/6 and TLR2/1 Heterodimers at the Cell Surface Determines Heterotypic Associations with CD36 and Intracellular Targeting

Triantafilou, M., Gamper, F. G. J., Haston, R. M., Mouratis, M. A., Morath, S., Härtung, T., & Triantafilou, K. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602794200 · Cited by 460 · see citing works

Models of white matter injury: Comparison of infectious, hypoxic‐ischemic, and excitotoxic insults

Hagberg, H., Peebles, D., & Mallard, C. E. (2002) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.10007 · Cited by 444 · see citing works

Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways

Hochrein, H., Schlatter, B., O’Keeffe, M. A., Wagner, C., Schmitz, F., Schiemann, M., Bauer, S., Suter, M., & Wagner, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403555101 · Cited by 439 · see citing works

Uterine DCs are crucial for decidua formation during embryo implantation in mice

Plaks, V., Birnberg, T., Berkutzki, T., Sela, S., BenYashar, A., Kalchenko, V., Mor, G., Keshet, E., Dekel, N., Neeman, M., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36682 · Cited by 381 · see citing works

Activation and regulation of Toll-like receptors 2 and 1 in human leprosy

Krutzik, S. R., Ochoa, M. T., Sieling, P. A., Uematsu, S., Ng, Y. W., Legaspi, A. J., Liu, P. T., Cole, S. T., Godowski, P. J., Maeda, Y., et al. (2003) · Nature Medicine · doi:10.1038/nm864 · Cited by 354 · see citing works

Human decidual NK cells form immature activating synapses and are not cytotoxic

Kopcow, H. D., Allan, D., Chen, X., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507835102 · Cited by 341 · see citing works

Toll-like receptors in inflammation, infection and cancer

Chen, K., Huang, J., Gong, W., Iribarren, P., Dunlop, N. M., & Wang, J. M. (2007) · International Immunopharmacology · doi:10.1016/j.intimp.2007.05.016 · Cited by 324 · see citing works

Immunocytochemical characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle

King, A., Wellings, V., Gardner, L., & Loke, Y. W. (1989) · Human Immunology · doi:10.1016/0198-8859(89)90060-8 · Cited by 321 · see citing works

TLR7/8-Mediated Activation of Human NK Cells Results in Accessory Cell-Dependent IFN-γ Production

Hart, O. M., Athié-Morales, V., O’Connor, G. M., & Gardiner, C. M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.3.1636 · Cited by 310 · see citing works

Engraftment of Bone Marrow from Severe Combined Immunodeficient (SCID) Mice Reverses the Reproductive Deficits in Natural Killer Cell–deficient tgε26 Mice

Guimond, M., Wang, B., & Croy, B. A. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.2.217 · Cited by 307 · see citing works

Divergent Trophoblast Responses to Bacterial Products Mediated by TLRs

Abrahams, V. M., Aldo, P. B., Kim, Y. M., Chavez, S. L., Chaiworapongsa, T., Romero, R. J., & Mor, G. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.7.4286 · Cited by 278 · see citing works

Roles of Toll‐like receptors in innate immune responses

Takeda, K., & Akira, S. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00458.x · Cited by 267 · see citing works

Role of TLR-2 in the Activation of Nuclear Factor κB by Oxidative Stress in Cardiac Myocytes

Frantz, S., Kelly, R. A., & Bourcier, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009160200 · Cited by 266 · see citing works

Dendritic Cells in the Human Decidua

Gardner, L. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.103.017574 · Cited by 257 · see citing works

Expression and regulation of the pattern recognition receptors Toll‐like receptor‐2 and Toll‐like receptor‐4 in the human placenta

Holmlund, U., Cebers, G., Dahlfors, A. R., Sandstedt, B., Bremme, K., Ekström, E. S., & Scheynius, A. (2002) · Immunology · doi:10.1046/j.1365-2567.2002.01491.x · Cited by 253 · see citing works

Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis

Kim, Y. M., Romero, R. J., Chaiworapongsa, T., Kim, G. J., Kim, J.-H., Kuivaniemi, H., Tromp, G. C., Espinoza, J., Bujold, E., Abrahams, V. M., et al. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.07.009 · Cited by 240 · see citing works

Trophoblast–Macrophage Interactions: a Regulatory Network for the Protection of Pregnancy

Fest, S., Aldo, P. B., Abrahams, V. M., et al. (2006) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2006.00446.x · Cited by 225 · see citing works

A Role for TLRs in the Regulation of Immune Cell Migration by First Trimester Trophoblast Cells

Abrahams, V. M., Visintin, I., Aldo, P. B., Guller, S. M., Romero, R. J., & Mor, G. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.12.8096 · Cited by 220 · see citing works

Uterine NK Cells Mediate Inflammation-Induced Fetal Demise in IL-10-Null Mice

Murphy, S. P., Fast, L. D., Hanna, N. N., & Sharma, S. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.6.4084 · Cited by 220 · see citing works

Association between the Asp299Gly Polymorphisms in the Toll-like Receptor 4 and Premature Births in the Finnish Population

Lorenz, E., Hallman, M., Marttila, R. H., et al. (2002) · Pediatric Research · doi:10.1203/00006450-200209000-00011 · Cited by 206 · see citing works

The Neurobiology of Infantile Autism

Ciaranello, A. L., & Ciaranello, R. D. (1995) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.18.030195.000533 · Cited by 184 · see citing works

Maternal poly I:C exposure during pregnancy regulates TNFα, BDNF, and NGF expression in neonatal brain and the maternal–fetal unit of the rat

Gilmore, J. H., Jarskog, L. F., & Vadlamudi, S. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.10.008 · Cited by 177 · see citing works

Maternal Effects on Schizophrenia Risk

Patterson, P. H. (2007) · Science · doi:10.1126/science.1150196 · Cited by 175 · see citing works

Toll-like receptor 4: A potential link between “danger signals,” the innate immune system, and preeclampsia?

Kim, Y. M., Romero, R. J., Oh, S. Y., Kim, C. J., Kilburn, B. A., Armant, D. R., Nien, J. K., Gómez, R., Mazor, M., Saito, S., et al. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.07.076 · Cited by 174 · see citing works

Myeloid Differentiation Factor 88–Dependent and –Independent Pathways in Toll‐Like Receptor Signaling

Akira, S., & Hoshino, K. (2003) · The Journal of Infectious Diseases · doi:10.1086/374749 · Cited by 165 · see citing works

Infection in the prediction and antibiotics in the prevention of spontaneous preterm labour and preterm birth

Lamont, R. (2003) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1046/j.1471-0528.2003.00034.x · Cited by 163 · see citing works

Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis.

Kumazaki, K., Nakayama, M., Yanagihara, I., Suehara, N., & Wada, Y. (2004) · Human Pathology · doi:10.1016/j.humpath.2003.08.027 · Cited by 157 · see citing works

Immunoregulatory cells in human decidua : morphology, immunohistochemistry and function

Bulmer, J. N., Pace, D., & Ritson, A. (1988) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:19881006 · Cited by 150 · see citing works

Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?

von Dadelszen, P., & Magee, L. A. (2002) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2002.810710.x · Cited by 145 · see citing works

Activation of Toll-like Receptors 2 or 3 and Preterm Delivery in the Mouse

Ilievski, V., Lu, S., & Hirsch, E. (2007) · Reproductive Sciences · doi:10.1177/1933719107302959 · Cited by 125 · see citing works

Preconceptional antibiotic treatment to prevent preterm birth in women with a previous preterm delivery

Espinoza, J., Erez, O., & Romero, R. J. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.11.050 · Cited by 117 · see citing works

Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C)

Abrahams, V. M. (2006) · Human Reproduction · doi:10.1093/humrep/del178 · Cited by 114 · see citing works

Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women

Genç, M., Vardhana, S. A., Delaney, M. L., Onderdonk, A. B., TUOMALA, R. E., Norwitz, E. R., & Witkin, S. S. (2004) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2004.02.010 · Cited by 113 · see citing works

Expression and Subcellular Localization of TLR-4 in Term and First Trimester Human Placenta

Beijar, E. C. E., Mallard, C. E., & Powell, T. L. (2005) · Placenta · doi:10.1016/j.placenta.2004.12.012 · Cited by 110 · see citing works

Immune Suppression and Th1/Th2 Balance in Pregnancy Revisited: A (Very) Personal Tribute to Tom Wegmann

Chaouat, G., Diallo, J. T., Voluménie, J. L., Menu, E., Gras, G. S., Delage, G. L., & Mognetti, B. (1997) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.1997.tb00255.x · Cited by 104 · see citing works

Chlamydia Heat Shock Protein 60 Induces Trophoblast Apoptosis through TLR4

Equils, O., Lu, D., Gatter, M. A., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.2.1257 · Cited by 97 · see citing works

Is the Trophoblast an Immune Regulator?: The Role of Toll-Like Receptors During Pregnancy

Mor, G., Romero, R. J., Aldo, P. B., & Abrahams, V. M. (2005) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v25.i5.30 · Cited by 95 · see citing works

TLR6 Modulates First Trimester Trophoblast Responses to Peptidoglycan

Abrahams, V. M., Aldo, P. B., Murphy, S. P., Visintin, I., Koga, K., Wilson, G., Romero, R. J., Sharma, S., & Mor, G. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.9.6035 · Cited by 94 · see citing works

Macrophage-activating lipopeptide-2 induces cyclooxygenase-2 and prostaglandin E2 via toll-like receptor 2 in human placental trophoblast cells

Mitsunari, M., Yoshida, S., Shoji, T., et al. (2006) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2006.02.003 · Cited by 92 · see citing works

Cell Type-specific Expression and Function of Toll-like Receptors 2 and 4 in Human Placenta: Implications in Fetal Infection

Ma, Y., Krikun, G., Abrahams, V. M., Mor, G., & Guller, S. M. (2007) · Placenta · doi:10.1016/j.placenta.2007.05.003 · Cited by 92 · see citing works

NOD Protein Expression and Function in First Trimester Trophoblast Cells

Costello, M. J., Joyce, S. K., & Abrahams, V. M. (2006) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2006.00447.x · Cited by 89 · see citing works

Dermatitis as a component of the fetal inflammatory response syndrome is associated with activation of Toll‐like receptors in epidermal keratinocytes

Kim, Y. M., Romero, R. J., Chaiworapongsa, T., Espinoza, J., Mor, G., & Kim, C. J. (2006) · Histopathology · doi:10.1111/j.1365-2559.2006.02542.x · Cited by 87 · see citing works

The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta

Holmlund, U., Wähämaa, H., Bachmayer, N., Bremme, K., Sverremark‐Ekström, E., & Palmblad, K. (2007) · Immunology · doi:10.1111/j.1365-2567.2007.02662.x · Cited by 83 · see citing works

Ureaplasma urealyticumModulates Endotoxin-Induced Cytokine Release by Human Monocytes Derived from Preterm and Term Newborns and Adults

Manimtim, W., Hasday, J. D., Hester, L., et al. (2001) · Infection and Immunity · doi:10.1128/iai.69.6.3906-3915.2001 · Cited by 82 · see citing works

Toll-like Receptor 2 Polymorphism Is Associated With Preterm Birth

Krediet, T. G., Wiertsema, S. P., Vossers, M. J., Hoeks, S. B. E. A., Fleer, A., Ruven, H. J. T., & Rijkers, G. T. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e31813c9401 · Cited by 79 · see citing works

Can medroxyprogesterone acetate alter Toll-like receptor expression in a mouse model of intrauterine inflammation?

Elovitz, M. A., & Mrinalini, C. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.05.043 · Cited by 78 · see citing works

Urogenital infection in preeclampsia

Hsu, C. D., & Witter, F. R. (1995) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(95)02373-k · Cited by 72 · see citing works

A Novel Three‐Dimensional In Vitro System to Study Trophoblast–Endothelium Cell Interactions

Aldo, P. B., Krikun, G., Visintin, I., Lockwood, C. J., Romero, R. J., & Mor, G. (2007) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2007.00493.x · Cited by 70 · see citing works

Toll‐like receptor signaling inhibits structural development of the distal fetal mouse lung

Prince, L. S., Dieperink, H. I., Okoh, V. O., Fierro-Perez, G. A., & Lallone, R. L. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20362 · Cited by 68 · see citing works

Ultraviolet‐inactivated human cytomegalovirus induces placental syncytiotrophoblast apoptosis in a Toll‐like receptor‐2 and tumour necrosis factor‐α dependent manner

Chan, G. C. T., & Guilbert, L. (2006) · The Journal of Pathology · doi:10.1002/path.2025 · Cited by 60 · see citing works

Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy

Goepfert, A. R., Varner, M. W., Ward, K. J., MacPherson, C., Klebanoff, M. A., Goldenberg, R. L., Mercer, B. M., Meis, P. J., Iams, J. D., Moawad, A., et al. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.03.053 · Cited by 55 · see citing works

Lipoteichoic acid induces preterm delivery in mice

Kajikawa, S., Kaga, N., Futamura, Y., et al. (1998) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/s1056-8719(98)00015-x · Cited by 53 · see citing works

Natural killer cells and reproduction

Moffett-King, A., Entrican, G., Ellis, S. A., Hutchinson, J. A., & Bainbridge, D. R. J. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02261-5 · Cited by 52 · see citing works

Immune signalling at the maternal—Fetal interface and trophoblast differentiation

WEGMANN, T., & Guilbert, L. J. (1992) · Developmental & Comparative Immunology · doi:10.1016/0145-305x(92)90026-9 · Cited by 51 · see citing works

Toll-like receptor-2 expression in normal and pathologic human placenta

Rindsjö, E., Holmlund, U., Sverremark‐Ekström, E., Papadogiannakis, N., & Scheynius, A. (2007) · Human Pathology · doi:10.1016/j.humpath.2006.09.009 · Cited by 49 · see citing works

The role of infection in preterm labour and birth

Lamont, R. (2003) · Hospital Medicine · doi:10.12968/hosp.2003.64.11.2343 · Cited by 48 · see citing works

TLR3-Involved Modulation of Pregnancy Tolerance in Double-Stranded RNA-Stimulated NOD/SCID Mice

Lin, Y., Liang, Z., Chen, Y., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4147 · Cited by 47 · see citing works

Toll-like receptor 3 agonist induces impairment of uterine vascular remodeling and fetal losses in CBA × DBA/2 mice

Zhang, J., Wei, H., Wu, D., & Tian, Z. (2006) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2006.10.005 · Cited by 46 · see citing works

LPS Induces Translocation of TLR4 in Amniotic Epithelium

Waldorf, K. M. A., Lucas, J., Kapur, R. P., & Stevens, A. M. (2006) · Placenta · doi:10.1016/j.placenta.2006.08.004 · Cited by 44 · see citing works

Macrophage-Trophoblast Interactions

Mor, G., Chavez, S. L., & Abrahams, V. M. (2006) · Humana Press eBooks · doi:10.1385/1-59259-989-3:149 · Cited by 42 · see citing works

Mechanism of Acute Fetal Cardiovascular Depression after Maternal Inflammatory Challenge in Mouse

Rounioja, S., Rasanen, J. P., Ojaniemi, M., et al. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62469-8 · Cited by 40 · see citing works

Expression of Allograft Inflammatory Factor‐1 in Mouse Uterus and Poly (I:C)‐induced Fetal Resorption

Shimada, S., Iwabuchi, K., Watano, K., et al. (2003) · American Journal of Reproductive Immunology · doi:10.1034/j.1600-0897.2003.00060.x · Cited by 34 · see citing works

Murine CD200+CK7+ trophoblasts in a poly (I:C)-induced embryo resorption model

Lin, Y., Zeng, Y., Di, J., et al. (2005) · Reproduction · doi:10.1530/rep.1.00575 · Cited by 33 · see citing works

Preeclampsia and Chlamydia Pneumoniae: Is There a Link?

Raynor, B. D., Bonney, E. A., Jang, K. T., et al. (2004) · Hypertension in Pregnancy · doi:10.1081/prg-120028284 · Cited by 31 · see citing works

Potential role of toll-like receptor 3 in a murine model of polyinosinic-polycytidylic acid-induced embryo resorption

Lin, Y., Zeng, Y., Zeng, S., et al. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.08.056 · Cited by 29 · see citing works

No cancer in cancers: Evolutionary trade-off between successful viviparity and tumor escape from the adaptive immune system

Hayakawa, S. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2005.12.010 · Cited by 27 · see citing works

Placental vascular disease and toll-like receptor 4 gene expression

Wang, X., Athayde, N., & Trudinger, B. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.09.009 · Cited by 22 · see citing works

Th1/Th2 Balance of the Implantation Site in Humans

Saito, S., Miyazaki, S., & Sasaki, Y. (2007) · Springer eBooks · doi:10.1007/0-387-34944-8_4 · Cited by 20 · see citing works

Submicroscopic infection of placenta by Plasmodium produces Th1/Th2 cytokine imbalance, inflammation and hypoxia in women from north-west Colombia

Agudelo, O. M., Aristizabal, B. H., Yanow, S. K., Arango, E., Carmona-Fonseca, J., & Maestre, A. (2014) · Malaria Journal · doi:10.1186/1475-2875-13-122 · Cited by 37 · see citing works

Comparison of Immunosuppressive Properties of Hydatidiform Mole Decidua and Trophoblast Extracts

Bennett, W. A., Brackin, M. N., Long, C. A., et al. (1996) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.1996.tb00144.x · Cited by 4 · see citing works

Interaction of mouse ectoplacental cone trophoblast and uterine decidua in vitro

Babiarz, B., Romagnano, L., & Kurilla, G. (1992) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/bf02634133 · Cited by 23 · see citing works

Effects of a-momorcharin on human trophoblast and deciduacells in vitro

Han, W. (1991) · Zhongguo yaolixue yu dulixue zazhi

Tissue interactions in first trimester trophoblast-decidua co-cultures

Vićovac, L., Papic, N., & Aplin, J. (1993) · Placenta · doi:10.1016/s0143-4004(05)80296-6 · Cited by 13 · see citing works

The distribution of tissue inhibitor of metalloproteinases-2 (timp-2) in decidua and trophoblast of early human pregnancy

Ruck, P., Marzusch, K., Kröber, S. M., et al. (1997) · Placenta · doi:10.1016/s0143-4004(97)80083-5 · Cited by 6 · see citing works