Cited by 128Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentYouth, Drugs, and Violence

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Psychopathology in methamphetamine-dependent adults 3 years after treatment

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GLASNER‐EDWARDS, SUZETTE, MOONEY, LARISSA J., MARINELLI‐CASEY, PATRICIA, HILLHOUSE, MAUREEN, ANG, ALFONSO, RAWSON, RICHARD A., THE METHAMPHETAMINE TREATMENT PROJECT CORPORATE AUTHORS·2010·Drug and Alcohol Review

DOI 10.1111/j.1465-3362.2009.00081.xPMC PMC3772133

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Abstract

INTRODUCTION AND AIMS: Although psychiatric symptoms are frequently observed in methamphetamine (MA) users, little is known about the prevalence of psychiatric disorders in MA-dependent individuals. This is the first study to examine the association of psychiatric disorders with substance use and psychosocial functioning in a large sample of MA users 3 years after treatment. We predicted that psychiatric diagnoses and severity would be associated with substance use and poorer overall functioning over the 3 year post-treatment course. DESIGN AND METHODS: Participants (N = 526) received psychosocial treatment for MA dependence as part of the Methamphetamine Treatment Project and were reassessed for psychosocial functioning and substance use at a mean of 3 years after treatment initiation. DSM-IV psychiatric diagnoses were assessed at follow-up using the Mini-International Neuropsychiatric Interview. Psychosocial functioning was assessed using the Addiction Severity Index. RESULTS: Overall, 48.1% of the sample met criteria for a current or past psychiatric disorder other than a substance use disorder. Consistent with prior reports from clinical samples of cocaine users, this rate was largely accounted for by mood disorders, anxiety disorders and antisocial personality. Those with an Axis I psychiatric disorder evidenced increased MA use and greater functional impairment over time relative to those without a psychiatric disorder. DISCUSSION AND CONCLUSIONS: This initial investigation of psychiatric diagnoses in MA users after treatment indicates elevated rates of Axis I and II disorders in this population and underscores the need for integrated psychiatric assessment and intervention in drug abuse treatment settings.

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Authors: GLASNER‐EDWARDS, S., MOONEY, L. J., MARINELLI‐CASEY, P., HILLHOUSE, M., ANG, A., RAWSON, R. A., & THE METHAMPHETAMINE TREATMENT PROJECT CORPORATE AUTHORS
Affiliations: University of California, Los Angeles (US)
ORCID: MOONEY, LARISSA J.
RAWSON, RICHARD A.
Venue: Drug and Alcohol Review
Publisher: Wiley
Published: 2010-01
Volume: 29
Issue: 1
Pages: 12-20
ISSN: 0959-5236 (ISSN-L)
1465-3362
DOI: 10.1111/j.1465-3362.2009.00081.x
PMC: PMC3772133
OpenAlex: W1941604713
Cited by: 128
References: 35
Citations by year: 2026: 6 · 2025: 1 · 2024: 7 · 2023: 3 · 2022: 6 · 2021: 4 · 2020: 32 · 2019: 2 · 2018: 9 · 2017: 6 · 2016: 6 · 2015: 8 · 2014: 12 · 2013: 9 · 2012: 7
FWCI: 6.05
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Drug and Alcohol Review (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse (K23DA020085)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
Keywords: methamphetamine dependence, psychiatric comorbidity, mood disorders, anxiety disorders, antisocial personality disorder, psychosocial functioning, substance use
MeSH terms: Adult, Mental Disorders, Female, Follow-Up Studies, Humans, Male, Methamphetamine, Psychiatric Status Rating Scales, Severity of Illness Index, Prevalence, Diagnosis, Dual (Psychiatry), Amphetamine-Related Disorders, Diagnostic and Statistical Manual of Mental Disorders

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Psychopathology in methamphetamine-dependent adults 3 years after treatment

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