Efficacy of indirect dopamine agonists for psychostimulant dependence: a systematic review and meta-analysis of randomized controlled trials
Abstract
Psychostimulant dependence is characterized by dopamine deficit, which could be reversed with indirect dopamine agonists (IDAs). A systematic review and meta-analysis of randomized, parallel-group, placebo-controlled clinical trials assessing the efficacy of IDAs in psychostimulant-dependent individuals were conducted. The study outcomes were psychostimulant abstinence, assessed by means of urinalysis, and retention in treatment. Risk of bias was determined using a Cochrane Collaboration instrument. Twenty-nine studies fulfilled the inclusion criteria, involving 2,467 participants. Compared with placebo, IDAs increased psychostimulant abstinence (standardized mean difference = 0.20; 95% confidence interval, 0.06-0.35; p = .005) but did not increase retention in treatment. Efficacy was larger in comorbid heroin-dependent individuals and was positively related with treatment length. No study was considered fully free of bias. IDAs appear to be efficacious for reducing psychostimulant use but did not improve retention. Efforts should be undertaken to reduce the risk of bias of clinical trials with psychostimulant-dependent individuals.
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Non-selective dopamine agonists have at best limited efficacy for cocaine addiction.
“While non-selective dopamine agonists have, at best, limited efficacy for cocaine addiction (Amato et al., 2011; Perez-Mana et al., 2011), a recent study showed that levodopa/carbidopa was most effective when combined with a behavioral treatment that uses positive reinforcement to shift behavior (Schmitz et al., 2008)”
From Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity (2014) · cites this paper as Perez-Mana et al., 2011
Cites
3 retracted
Dopamine agonists for cocaine dependence
Soares, B. G., Reisser, A. A. L., Farrell, M., & de Lima, M. S. (2003) · doi:10.1002/14651858.cd003352 · Cited by 83 · see citing works
RetractedAntidepressants for cocaine dependence
de Lima, M. S., Farrell, M., Reisser, A. A. L., & Soares, B. G. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002950 · Cited by 79 · see citing works
RetractedAnticonvulsants for cocaine dependence
Minozzi, S., Amato, L., Davoli, M., Farrell, M., Reisser, A. A. L., Pani, P. P., de Lima, M. S., Soares, B. G., & Vecchi, S. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006754.pub2 · Cited by 56 · see citing works
RetractedCochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048 · see citing works
Pharmacological interventions for somatoform disorders in adults
Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,361 · see citing works
Assessing the quality of controlled clinical trials
Jüni, P., Altman, D. G., & Egger, M. (2001) · BMJ · doi:10.1136/bmj.323.7303.42 · Cited by 3,309 · see citing works
Systematic review and meta-analysis
Gillies, A. (2019) · CRC Press eBooks · doi:10.1201/9781315377315-19 · Cited by 2,659 · see citing works
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Mattick, R. P., Breen, C. L., Kimber, J., & Davoli, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub4 · Cited by 2,312 · see citing works
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Mattick, R. P., Breen, C., Kimber, J., & Davoli, M. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002209.pub2 · Cited by 1,654 · see citing works
A double‐blind, placebo‐controlled trial
Pinals, R. S., Kaplan, S. B., Lawson, J. G., & Hepburn, B. (1986) · Arthritis & Rheumatism · doi:10.1002/art.1780291202 · Cited by 1,355 · see citing works
Results from the 2003 National Survey on Drug Use and Health: National Findings
(2004) · PsycEXTRA Dataset · doi:10.1037/e400442005-001 · Cited by 1,245 · see citing works
Mechanisms of neurotransmitter release by amphetamines: A review
Sulzer, D. L., Sonders, M. S., Poulsen, N. W., & Galli, A. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.04.003 · Cited by 1,212 · see citing works
Results From the 2008 National Survey on Drug Use and Health: National Findings
(2009) · PsycEXTRA Dataset · doi:10.1037/e592592009-001 · Cited by 1,178 · see citing works
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications
Volkow, N. D., Fowler, J. S., Wang, G.-J., & Swanson, J. M. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001507 · Cited by 1,101 · see citing works
Wise, R. A. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80079-1 · Cited by 1,072 · see citing works
The dopamine hypothesis of the reinforcing properties of cocaine
Kuhar, M. J., Ritz, M. C., & Boja, J. W. (1991) · Trends in Neurosciences · doi:10.1016/0166-2236(91)90141-g · Cited by 989 · see citing works
Association of Dopamine Transporter Reduction With Psychomotor Impairment in Methamphetamine Abusers
Volkow, N. D., Chang, L. L., Wang, G., Fowler, J. S., Leonido–Yee, M., Franceschi, D., Sedler, M. J., Gatley, S. J., HITZEMANN, R. J., Ding, Y. ‐., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.377 · Cited by 984 · see citing works
Volkow, N. D., Fowler, J. S., Wang, G., Hitzemann, R., Logan, J., Schlyer, D. J., Dewey, S. L., & Wolf, A. P. (1993) · Synapse · doi:10.1002/syn.890140210 · Cited by 924 · see citing works
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects
Volkow, N. D., Wang, G.-J., Fowler, J. S., Logan, J., Gatley, S. J., Hitzemann, R., Chen, A. D., Dewey, S. L., & Pappas, N. (1997) · Nature · doi:10.1038/386830a0 · Cited by 854 · see citing works
Robinson, K. A., & Dickersin, K. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.1.150 · Cited by 833 · see citing works
Structural Abnormalities in the Brains of Human Subjects Who Use Methamphetamine
Thompson, P. M., Hayashi, K. M., Simon, S. L., Geaga, J. A., Hong, M., Sui, Y., Lee, J. Y., Toga, A. W., Ling, W. W., & London, E. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0713-04.2004 · Cited by 760 · see citing works
Striatal dopamine nerve terminal markers in human, chronic methamphetamine users
Wilson, J. M., Kalasinsky, K. S., Levey, A. I., Bergeron, C., Reiber, G. D., Anthony, R. M., Schmunk, G. A., Shannak, K. S., Haycock, J. W., & Kish, S. J. (1996) · Nature Medicine · doi:10.1038/nm0696-699 · Cited by 718 · see citing works
Relationship between subjective effects of cocaine and dopamine transporter occupancy
Volkow, N. D., Wang, G., Fischman, M. W., Foltin, R. W., Fowler, J. S., Abumrad, N. N., Vitkun, S. A., Logan, J., Gatley, S. J., Pappas, N. R., et al. (1997) · Nature · doi:10.1038/386827a0 · Cited by 646 · see citing works
Psychiatric Diagnoses of Treatment-Seeking Cocaine Abusers
Rounsaville, B. J. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810250045005 · Cited by 605 · see citing works
Rossetti, Z. L., Hmaidan, Y., & GESSA, G. L. (1992) · European Journal of Pharmacology · doi:10.1016/0014-2999(92)90706-a · Cited by 526 · see citing works
Wagner, G. C., Ricaurte, G. A., Seiden, L. S., Schuster, C. R., Miller, R. J., & Westley, J. (1980) · Brain Research · doi:10.1016/0006-8993(80)91265-2 · Cited by 523 · see citing works
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Mattick, R. P., Kimber, J., Breen, C., & Davoli, M. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub3 · Cited by 501 · see citing works
Psychiatric Symptoms in Methamphetamine Users
Zweben, J. E., Cohen, J. B., Christian, D., Galloway, G. P., Salinardi, M., Parent, D., Iguchi, M. Y., & Methamphetamine Treatment Project (2004) · American Journal on Addictions · doi:10.1080/10550490490436055 · Cited by 469 · see citing works
Structural and metabolic brain changes in the striatum associated with methamphetamine abuse
Chang, L., Alicata, D., Ernst, T. M., & Volkow, N. D. (2007) · Addiction · doi:10.1111/j.1360-0443.2006.01782.x · Cited by 431 · see citing works
Effects of chronic cocaine abuse on postsynaptic dopamine receptors
(1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.6.719 · Cited by 421 · see citing works
Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients
Carroll, K. M., Fenton, L. R., Ball, S. A., Nich, C., Frankforter, T. L., Shi, J. M., & Rounsaville, B. J. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.3.264 · Cited by 410 · see citing works
The neurobiology of addiction: a neuroadaptational view relevant for diagnosis
Koob, G. F. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01586.x · Cited by 397 · see citing works
A Double-Blind, Placebo-Controlled Trial of Modafinil for Cocaine Dependence
Dackis, C. A., Kampman, K. M., Lynch, K. G., Pettinati, H. M., & O'Brien, C. P. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300600 · Cited by 391 · see citing works
Lee, B., London, E. D., Poldrack, R. A., Farahi, J., Nacca, A., Monterosso, J. R., Mumford, J. A., Bokarius, A. V., Dahlbom, M., Mukherjee, J., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3765-09.2009 · Cited by 374 · see citing works
Schubiner, H., Saules, K., Arfken, C., Johanson, C., Schuster, C., Lockhart, N. A., Edwards, A., Donlin, J., & Pihlgren, E. M. (2002) · Experimental and clinical psychopharmacology · doi:10.1037//1064-1297.10.3.286 · Cited by 277 · see citing works
Efficacy of antidepressants in substance use disorders with and without comorbid depression
Torrens, M., Fonseca, F., Mateu-Codina, G., & Farré, M. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.09.004 · Cited by 262 · see citing works
Monoamine transporters and psychostimulant addiction
Howell, L. L., & Kimmel, H. L. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.003 · Cited by 249 · see citing works
Schubiner, H., Downey, K. K., Arfken, C. L., Johanson, C.-E., Schuster, C. R., Lockhart, N., Edwards, A., Donlin, J., & Pihlgren, E. (2002) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.10.3.286 · Cited by 249 · see citing works
Dextroamphetamine for Cocaine-Dependence Treatment: A Double-Blind Randomized Clinical Trial
Grabowski, J., Rhoades, H., Schmitz, J., Stotts, A., Daruzska, L. A., Creson, D., & Moeller, F. G. (2001) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200110000-00010 · Cited by 243 · see citing works
Data Extraction Errors in Meta-analyses That Use Standardized Mean Differences
Gøtzsche, P. C., Hróbjartsson, A., Marić, K., & Tendal, B. (2007) · JAMA · doi:10.1001/jama.298.4.430 · Cited by 238 · see citing works
Modafinil for the treatment of cocaine dependence
Anderson, A. L., Reid, M. S., Li, S.-H., Holmes, T., Shemanski, L., Slee, A., Smith, E. V., Kahn, R., Chiang, N., Vocci, F., et al. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.04.015 · Cited by 235 · see citing works
Bupropion for the treatment of methamphetamine dependence
Elkashef, A. M., Rawson, R. A., Anderson, A. L., Li, S.-H., Holmes, T., Smith, E. V., Chiang, N., Kahn, R., Vocci, F., Ling, W., et al. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301481 · Cited by 234 · see citing works
Disulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts
Petrakis, I. L., Carroll, K. M., Nich, C., Gordon, L. T., McCance‐Katz, E. F., Frankforter, T. L., & Rounsaville, B. J. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9522198.x · Cited by 229 · see citing works
Levin, F. R., Evans, S. M., Brooks, D. J., & Garawi, F. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.07.004 · Cited by 220 · see citing works
Replacement Medication for Cocaine Dependence
Grabowski, J. G., Roache, J. D., Schmitz, J. M., Rhoades, H. M., Creson, D. L., & Korszun, A. (1997) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199712000-00008 · Cited by 191 · see citing works
Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study
Dackis, C. A., Lynch, K. G., Yu, E., Samaha, F. F., Kampman, K. M., Cornish, J., Rowan, A. B., Poole, S. A., White, L., & O’Brien, C. P. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00335-6 · Cited by 186 · see citing works
Grabowski, J., Rhoades, H., Stotts, A., Cowan, K., Kopecky, C., Dougherty, A., Moeller, F. G., Hassan, S., & Schmitz, J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300392 · Cited by 185 · see citing works
A Comparison of Aripiprazole, Methylphenidate, and Placebo for Amphetamine Dependence
Tiihonen, J., Kuoppasalmi, K. I., Föhr, J., Tuomola, P., Kuikanmäki, O., Vorma, H., Sokero, P., Haukka, J. K., & Meririnne, E. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.1.160 · Cited by 178 · see citing works
Smoked Cocaine Self-Administration is Decreased by Modafinil
Hart, C. L., Haney, M., Vosburg, S. K., Rubin, E., & Foltin, R. W. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301472 · Cited by 174 · see citing works
A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients
Margolin, A., Kosten, T. R., Avants, S. K., Wilkins, J., Ling, W., Beckson, M., Arndt, I. O., Cornish, J., Ascher, J. A., Li, S.-H., et al. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01198-6 · Cited by 168 · see citing works
Poling, J. C., Oliveto, A. H., Petry, N. M., Sofuoglu, M., Gonsai, K., Gonzalez, G. M., Martell, B. A., & Kosten, T. R. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.2.219 · Cited by 167 · see citing works
Bupropion Reduces Methamphetamine-Induced Subjective Effects and Cue-Induced Craving
Newton, T. F., Roache, J. D., Garza, R. D. L., FONG, T. W., Wallace, C. L., Li, S.-H., Elkashef, A. M., Chiang, N., & Kahn, R. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300979 · Cited by 163 · see citing works
Rothman, R. B., & Glowa, J. R. (1995) · Molecular Neurobiology · doi:10.1007/bf02740680 · Cited by 162 · see citing works
George, T. P., Chawarski, M. C., Pakes, J., Carroll, K. M., Kosten, T. R., & Schottenfeld, R. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00310-8 · Cited by 159 · see citing works
A double‐blind, placebo‐controlled trial of modafinil (200 mg/day) for methamphetamine dependence
Shearer, J., Darke, S., Rodgers, C., Slade, T., Van Beek, I., Lewis, J., Brady, D., McKetin, R., Mattick, R. P., & Wodak, A. (2009) · Addiction · doi:10.1111/j.1360-0443.2008.02437.x · Cited by 159 · see citing works
Cartier, J., Farabee, D. J., & PRENDERGAST, M. L. (2006) · Journal of Interpersonal Violence · doi:10.1177/0886260505285724 · Cited by 154 · see citing works
Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence
SHOPTAW, S. J., Heinzerling, K. G., Rotheram-Fuller, E. J., Steward, T., Wang, J., Swanson, A., Garza, R. D. L., Newton, T., & Ling, W. W. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.03.010 · Cited by 150 · see citing works
Informed consent in experimentation involving mentally impaired persons: ethical issues.
Petrini, C. (2010) · PubMed · doi:10.4415/ann_10_04_09 · Cited by 148 · see citing works
Camp, D. M., Browman, K. E., & Robinson, T. E. (1994) · Brain Research · doi:10.1016/0006-8993(94)90523-1 · Cited by 147 · see citing works
Pilot randomized double blind placebo‐controlled study of dexamphetamine for cocaine dependence
Shearer, J., WODAK, A. D., van Beek, I., Mattick, R. P., & Lewis, J. E. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00447.x · Cited by 142 · see citing works
Efficacy of Psychostimulant Drugs for Cocaine Dependence
Cervelló, X. C., Casas, M., Pérez‐Mañá, C., Roncero, C., Vidal, X., & Capellà, D. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007380.pub3 · Cited by 130 · see citing works
Self-citationPsychopathology in methamphetamine-dependent adults 3 years after treatment
GLASNER‐EDWARDS, S., MOONEY, L. J., MARINELLI‐CASEY, P., HILLHOUSE, M., ANG, A., RAWSON, R. A., & THE METHAMPHETAMINE TREATMENT PROJECT CORPORATE AUTHORS (2010) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2009.00081.x · Cited by 128 · see citing works
Anticonvulsants for cocaine dependence
Minozzi, S., Cinquini, M., Amato, L., Davoli, M., Farrell, M., Pani, P. P., & Vecchi, S. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006754.pub4 · Cited by 128 · see citing works
Kaye, S. S., Darke, S. G., Duflou, J. A., & McKetin, R. (2008) · Addiction · doi:10.1111/j.1360-0443.2008.02231.x · Cited by 128 · see citing works
Marek, G. J., Vosmer, G., & Seiden, L. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90467-p · Cited by 126 · see citing works
Effects of oral methamphetamine on cocaine use: A randomized, double-blind, placebo-controlled trial
Mooney, M. E., Herin, D. V., Schmitz, J. M., Moukaddam, N., Green, C. E., & Grabowski, J. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.10.016 · Cited by 124 · see citing works
Levodopa pharmacotherapy for cocaine dependence: choosing the optimal behavioral therapy platform
Schmitz, J. M., Mooney, M. E., Moeller, F. G., Stotts, A. L., Green, C., & Grabowski, J. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.11.004 · Cited by 124 · see citing works
Antipsychotic medications for cocaine dependence
Indave, B. I., Minozzi, S., Pani, P. P., & Amato, L. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006306.pub3 · Cited by 122 · see citing works
Negus, S. S., & Mello, N. K. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00339-3 · Cited by 120 · see citing works
Cocaine uptake is decreased in the brain of detoxified cocaine abusers
Volkow, N. (1996) · Neuropsychopharmacology · doi:10.1016/0893-133x(95)00073-m · Cited by 120 · see citing works
Disulfiram effects on acute cocaine administration
McCance‐Katz, E. F., Kosten, T. R., & Jatlow, P. L. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00050-7 · Cited by 106 · see citing works
Negus, S. S., & Mello, N. K. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1409-y · Cited by 101 · see citing works
Stereoselectivity and isoenzyme selectivity of monoamine oxidase inhibitors
Robinson, J. B. (1985) · Biochemical Pharmacology · doi:10.1016/0006-2952(85)90201-1 · Cited by 96 · see citing works
Pettinati, H. M., Kampman, K. M., Lynch, K. G., Xie, H., Dackis, C., Rabinowitz, A. R., & O′Brien, C. P. (2008) · Addictive Behaviors · doi:10.1016/j.addbeh.2007.11.011 · Cited by 95 · see citing works
Mortality among amphetamine users: A systematic review of cohort studies
Singleton, J., Degenhardt, L. J., Hall, W., & Zábranský, T. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.05.028 · Cited by 93 · see citing works
Trafficking of dopamine transporters in psychostimulant actions
Zahniser, N. R., & Sorkin, A. D. (2009) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2009.01.004 · Cited by 86 · see citing works
Modafinil and Cocaine Interactions
Malcolm, R. J., Swayngim, K. D., Donovan, J. L., DeVane, C. L., Elkashef, A. M., Chiang, N., Khan, R., Mojsiak, J., Myrick, D. H., Hedden, S. L., et al. (2006) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990600920425 · Cited by 85 · see citing works
Negus, S. S., Mello, N. K., Blough, B. E., Baumann, M. H., & Rothman, R. B. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.107383 · Cited by 78 · see citing works
Tendal, B., Higgins, J. P. T., Juni, P., Hrobjartsson, A., Trelle, S., Nuesch, E., Wandel, S., Jorgensen, A. W., Gesser, K., Ilsoe-Kristensen, S., et al. (2009) · BMJ · doi:10.1136/bmj.b3128 · Cited by 77 · see citing works
Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans
Hameedi, F. A., Rosen, M. I., McCance‐Katz, E. F., McMahon, T. J., Price, L. H., Jatlow, P. I., Woods, S. W., & Kosten, T. R. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00361-6 · Cited by 74 · see citing works
Cervelló, X. C., Casas, M., Vidal, X., Bosch, R., Roncero, C., Ramos‐Quiroga, J. A., & Capellà, D. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01943.x · Cited by 74 · see citing works
Self-citationGoldstein, A. C., Eiduson, S., Geller, E., Yuwiler, A., & Eiduson, B. T. (1965) · The American Journal of Psychology · doi:10.2307/1420526 · Cited by 66 · see citing works
Psychosocial approaches to psychostimulant dependence: A systematic review
Shearer, J. (2006) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2006.06.012 · Cited by 64 · see citing works
Cocaine-related fatalities in New South Wales, Australia 1993–2002
Darke, S. G., Kaye, S. S., & Duflou, J. A. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.07.004 · Cited by 63 · see citing works
Receptor-Binding and Pharmacokinetic Properties of Dopaminergic Agonists
Kvernmo, T., Houben, J. M., & Sylte, I. (2008) · Current Topics in Medicinal Chemistry · doi:10.2174/156802608785161457 · Cited by 61 · see citing works
Mazindol treatment for cocaine dependence
Stine, S. M., Krystal, J. H., Kosten, T. R., & Charney, D. S. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01174-4 · Cited by 58 · see citing works
Mazindol for Relapse Prevention to Cocaine Abuse in Methadone-Maintained Patients
Margolin, A., Avants, S. K., & Kosten, T. R. (1995) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952999509002711 · Cited by 54 · see citing works
Elkashef, A., Fudala, P., Gorgon, L., Li, S.-H., Kahn, R., Chiang, N., Vocci, F., Collins, J., Jones, K., Boardman, K., et al. (2006) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.04.010 · Cited by 54 · see citing works
Shoptaw, S., Heinzerling, K. G., Rotheram-Fuller, E., Kao, U. H., Wang, P.-C., Bholat, M. A., & Ling, W. (2008) · Journal of Addictive Diseases · doi:10.1300/j069v27n01_02 · Cited by 54 · see citing works
Randomized, placebo-controlled trial
Abdukareem, A. A. (2004) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2004.145 · Cited by 54 · see citing works
A meta‐analysis of marijuana, cocaine and opiate toxicology study findings among homicide victims
Kuhns, J. B., Wilson, D. B., Maguire, E. R., Ainsworth, S. A., & Clodfelter, T. A. (2009) · Addiction · doi:10.1111/j.1360-0443.2009.02583.x · Cited by 48 · see citing works
SHOPTAW, S. J., Watson, D. W., Reiber, C., Rawson, R. A., Montgomery, M. A., Majewska, M. D., & Ling, W. W. (2005) · Addiction · doi:10.1111/j.1360-0443.2005.00991.x · Cited by 47 · see citing works
National Case-Control Study of Homicide Offending and Methamphetamine Use
Stretesky, P. B. (2008) · Journal of Interpersonal Violence · doi:10.1177/0886260508325011 · Cited by 46 · see citing works
A Comparison of Aripiprazole, Methylphenidate, and Placebo for Amphetamine Dependence
Tiihonen, J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.164.1.160 · Cited by 43 · see citing works
Follow-Up Study of Crack Cocaine Users: Situation of the Patients after 2, 5, and 12 Years
Dias, A. C., Ribeiro, M., Dunn, J., Sesso, R., & Laranjeira, R. (2008) · Substance Abuse · doi:10.1080/08897070802218125 · Cited by 42 · see citing works
Mooney, M. E., Schmitz, J. M., Moeller, F. G., & Grabowski, J. G. (2006) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.10.011 · Cited by 38 · see citing works
Physical and mental health problems in amphetamine users from metropolitan Adelaide, Australia
Vincent, N. C., Shoobridge, J., Ask, A., ALLSOP, S. J., & Ali, R. L. (1998) · Drug and Alcohol Review · doi:10.1080/09595239800186991 · Cited by 38 · see citing works
The principles of agonist pharmacotherapy for psychostimulant dependence
Shearer, J. (2008) · Drug and Alcohol Review · doi:10.1080/09595230801927372 · Cited by 37 · see citing works
Antipsychotic medications for cocaine dependence
Amato, L., Minozzi, S., Pani, P., & Davoli, M. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006306 · Cited by 37 · see citing works
Anticonvulsant drugs in cocaine dependence: A systematic review and meta-analysis
Alvarez, Y., Farré, M., Fonseca, F., & Torrens, M. (2009) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2009.07.001 · Cited by 31 · see citing works
Psychostimulant Abuse: The Case for Combined Behavioral and Pharmacological Treatments
Stitzer, M. L., & WALSH, S. L. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00436-4 · Cited by 26 · see citing works
Research Issues Related to Development of Medications for Treatment of Cocaine Addiction
Klein, M. B. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb08223.x · Cited by 25 · see citing works
Turner, T. H. (1988) · The British Journal of Psychiatry · doi:10.1192/s0007125000221314 · Cited by 16 · see citing works
Antidepressants for cocaine dependence (Withdrawn Paper. 2010, art no. CD002950)
de Lima, M. S., Farrell, M., Reisser, A. A. L., & Soares, B. G. (2010) · Research Portal (King's College London) · Cited by 16 · see citing works
Pavarin, R. M. (2008) · PubMed · Cited by 15 · see citing works
Margolin, A., Avants, S. K., Malison, R. T., & Kosten, T. R. (1997) · Substance Abuse · doi:10.1080/08897079709511358 · Cited by 11 · see citing works
Dopamine agonists for cocaine dependence (Withdrawn Paper. 2010, art no. CD003352)
Soares, B. G., Reisser, A. A. L., Farrell, M., & de Lima, M. S. (2010) · Research Portal (King's College London) · Cited by 11 · see citing works
Perry, E. B., Gil, R. B., Miles, D., Brenner, L. M., Macdougall, L., Johnson, R., Degen, K. C., Gueorguieva, R. V., Petrakis, I. L., Krystal, J. H., et al. (2005) · Journal of Dual Diagnosis · doi:10.1300/j374v01n01_04 · Cited by 7 · see citing works
A simple method for converting an odds ratio to effect size for use in meta-analysis
Chinn, S. (2000) · Statistics in Medicine · doi:10.1002/1097-0258(20001130)19:22
Flagged first, then by citations
1 of the 110 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Kennedy, D. O., & Wightman, E. L. (2011) · Advances in Nutrition · doi:10.3945/an.110.000117 · Cited by 684 · see citing works
Meader, N., King, K., Llewellyn, A., Norman, G., Brown, J., Rodgers, M., Moe-Byrne, T., Higgins, J., Sowden, A., & Stewart, G. B. (2014) · Systematic Reviews · doi:10.1186/2046-4053-3-82 · Cited by 560 · see citing works
Ashok, A. H., Mizuno, Y., Volkow, N. D., & Howes, O. D. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0135 · Cited by 330 · see citing works
Treatment of stimulant use disorder: A systematic review of reviews
Ronsley, C., Nolan, S., Knight, R., Hayashi, K., Klimas, J., Walley, A., Wood, E., & Fairbairn, N. (2020) · PLOS ONE · doi:10.1371/journal.pone.0234809 · Cited by 222 · see citing works
Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity
Trifilieff, P., & Martinez, D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.06.031 · Cited by 171 · see citing works
Insights from Preclinical Choice Models on Treating Drug Addiction
Banks, M. L., & Negus, S. S. (2016) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2016.11.002 · Cited by 144 · see citing works
Wang, L., Min, J. E., Krebs, E., Evans, E., Huang, D. Y. C., Liu, L., Hser, Y., & Nosyk, B. (2017) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2017.07.009 · Cited by 128 · see citing works
Efficacy of psychostimulant drugs for amphetamine abuse or dependence
Pérez‐Mañá, C., Cervelló, X. C., Torrens, M., Capellà, D., & Farré, M. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009695.pub2 · Cited by 93 · see citing works
Self-citationA methodological review of meta-analyses of the effectiveness of clinical psychology treatments
Rubio‐Aparicio, M., Marín‐Martínez, F., Sánchez‐Meca, J., & López-López, J. A. (2017) · Behavior Research Methods · doi:10.3758/s13428-017-0973-8 · Cited by 93 · see citing works
Pharmacotherapeutic strategies for treating cocaine use disorder—what do we have to offer?
Brandt, L., Chao, T. W.-C., Comer, S. D., & LEVIN, F. R. (2020) · Addiction · doi:10.1111/add.15242 · Cited by 85 · see citing works
Future pharmacological treatments for substance use disorders
Forray, A., & Sofuoglu, M. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04474.x · Cited by 65 · see citing works
Bhatt, M., Zielinski, L., Baker-Beal, L., Bhatnagar, N., Mouravska, N., Laplante, P., Worster, A., Thabane, L., & Samaan, Z. (2016) · Systematic Reviews · doi:10.1186/s13643-016-0370-x · Cited by 56 · see citing works
Haile, C. N., Mahoney, J. J., Newton, T. F., & Garza, R. D. L. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.01.010 · Cited by 53 · see citing works
Hone‐Blanchet, A., Ciraulo, D. A., Pascual‐Leone, Á., & Fecteau, S. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.10.001 · Cited by 45 · see citing works
McCreary, A. C., Müller, C. P., & Filip, M. (2015) · International review of neurobiology · doi:10.1016/bs.irn.2015.02.008 · Cited by 44 · see citing works
Worhunsky, P. D., Matuskey, D., Gallezot, J., Gaiser, E., Nabulsi, N., Angarita, G. A., Calhoun, V. D., Malison, R. T., Potenza, M. N., & Carson, R. E. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.01.045 · Cited by 43 · see citing works
Drugs currently in Phase II clinical trials for cocaine addiction
Kim, J. H., & Lawrence, A. J. (2014) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2014.915312 · Cited by 40 · see citing works
Olière, S., Joliette-Riopel, A., Potvin, S., & Jutras‐Aswad, D. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00109 · Cited by 39 · see citing works
Banks, M. L., & Negus, S. S. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.259 · Cited by 39 · see citing works
Thomsen, M., Barrett, A. C., Butler, P., Negus, S. S., & Caine, S. B. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.117.241141 · Cited by 25 · see citing works
Nuijten, M., Blanken, P., van den Brink, W., & Hendriks, V. M. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115582151 · Cited by 23 · see citing works
Hutsell, B. A., Negus, S. S., & Banks, M. L. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.08.637 · Cited by 16 · see citing works
Antinori, S., Fattore, L., Saba, P., Fratta, W., Gessa, G. L., & Devoto, P. (2017) · Addiction Biology · doi:10.1111/adb.12509 · Cited by 11 · see citing works
Maintenance on naltrexone + amphetamine decreases cocaine-vs.-food choice in male rhesus monkeys
Moerke, M. J., Banks, M. L., Cheng, K., Rice, K. C., & Negus, S. S. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.09.020 · Cited by 10 · see citing works
Steele, T. W. E., & Eltit, J. M. (2018) · Psychopharmacology · doi:10.1007/s00213-018-5103-5 · Cited by 10 · see citing works
Efficacy of Psychostimulant Drugs for Amphetamine Abuse or Dependence
Pérez‐Mañá, C., Cervelló, X. C., Torrens, M., Capellà, D., & Farré, M. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009695 · Cited by 6 · see citing works
Self-citationBupropion in Comorbid Post-Traumatic Stress Disorder and Methamphetamine Use Disorder
Kneebusch, J., & Farhadian, S. (2024) · Journal of Pharmacy Practice · doi:10.1177/08971900241276698 · Cited by 1 · see citing works
García, Y. Á. (2015) · TDX (Tesis Doctorals en Xarxa)
Nuijten, M., Blanken, P., van de Wetering, B., Nuijen, B., van den Brink, W., & Hendriks, V. M. (2016) · Verslaving · doi:10.1007/s12501-016-0075-9
Nuijten, M. (2017) · Data Archiving and Networked Services (DANS)
Psychostimulant Dependence and Its Treatment
Layton, M. E., & Roll, J. M. (2015) · Springer eBooks · doi:10.1007/978-3-642-36172-2_7036
Psychostimulant Dependence and Its Treatment
Layton, M. E., & Roll, J. M. (2013) · Springer eBooks · doi:10.1007/978-3-642-27772-6_7036-1
Neurotransmitters and Neural Pathways
Schnall, J. S. (2026) · Springer eBooks · doi:10.1007/978-3-031-57159-6_33-1
- Authors
- Pérez-Mañá, C., Castells, X., Vidal, X., Casas, M., & Capellà, D.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- Venue
- Journal of Substance Abuse Treatment
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 40
- Issue
- 2
- Pages
- 109-122
- ISSN
- 0740-5472 (ISSN-L)
- OpenAlex
- W2015083139
- Semantic Scholar
- 6651d391024d92f17f083579921299377f755c35
- Cited by
- 33
- References
- 110
- Citations by year
- 2026: 1 · 2024: 1 · 2020: 2 · 2018: 1 · 2017: 8 · 2016: 5 · 2015: 5 · 2014: 2 · 2013: 4 · 2012: 3
- FWCI
- 0.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Substance Abuse Treatment (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Plan Nacional sobre Drogas
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- stimulant use disorder, cocaine dependence, abstinence, treatment retention, treatment duration, risk of bias
- MeSH terms
- Animals, Dopamine, Humans, Time Factors, Bias, Randomized Controlled Trials as Topic, Dopamine Agonists, Amphetamine-Related Disorders, Cocaine-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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