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Theory of Mind Performance in Children Correlates With Functional Specialization of a Brain Region for Thinking About Thoughts
Abstract
Thinking about other people's thoughts recruits a specific group of brain regions, including the temporo-parietal junctions (TPJ), precuneus (PC), and medial prefrontal cortex (MPFC). The same brain regions were recruited when children (N=20, 5-11 years) and adults (N=8) listened to descriptions of characters' mental states, compared to descriptions of physical events. Between ages 5 and 11 years, responses in the bilateral TPJ became increasingly specific to stories describing mental states as opposed to people's appearance and social relationships. Functional activity in the right TPJ was related to children's performance on a high level theory of mind task. These findings provide insights into the origin of neural mechanisms of theory of mind, and how behavioral and neural changes can be related in development.
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“Another emerging developmental pattern is a linear increase in TPJ responses during mentalizing (Gweon et al., 2012; van den Bos et al., 2011).”
From Risk-taking and social exclusion in adolescence: neural mechanisms underlying peer influences on decision-making (2013) · cites this paper as Gweon et al., 2012
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“6 To assess the relationship between scalar inference derivation and ToM, we compared patterns of neural activation during the ToM task for children in the passers and non-passers.”
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“In prior manuscripts, we have summarized over-all performance on the ToM booklet task by calculating the proportion of 2AFC and explanation questions answered correctly [ 1 , 19 ]; we have also calculated summary scores for subsets of questions (e.g., false belief items [1] ).”
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“All children performed an out-of-scanner verbal ToM assessment 53 .”
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“Accordingly, functional imaging studies in healthy children have consistently reported cortical activation in this region across various ToM tasks (e.g., Alkire et al., 2018; Bowman et al., 2019; Gweon et al., 2012; Moriguchi et al., 2007).”
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“Two developmental fMRI studies confirmed that the functional specialization of the rTPJ was associated with improved performance on ToM tasks (Gweon et al., 2012; Mukerji et al., 2019).”
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Evolving brain function and connectivity patterns during mentalizing in children and adults
Borbás, R., Dimanova, P., Saikkonen, D., Federici, E., Scatolin, S., & Raschle, N. M. (2026) · Communications Biology · doi:10.1038/s42003-026-09562-6
“However, while task-based activation during mentalizing is well-documented 8,16,23,44,45 , task-based functionalconnectivityremainslessunderstood.”
Metadata
- Authors
- Gweon, H., Dodell-Feder, D., Bedny, M., & Saxe, R.
- Affiliations
- Massachusetts Institute of Technology
- Harvard University
- Massachusetts Institute of Technology (US)
- Venue
- Child Development
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-11-01
- Volume
- 83
- Issue
- 6
- Pages
- 1853-1868
- ISSN
- 0009-3920 (ISSN-L)
- 1467-8624
- OpenAlex
- W2113635677
- Cited by
- 206
- References
- 70
- Citations by year
- 2026: 6 · 2025: 17 · 2024: 15 · 2023: 14 · 2022: 14 · 2021: 14 · 2020: 12 · 2019: 14 · 2018: 29 · 2017: 13 · 2016: 14 · 2015: 17 · 2014: 12 · 2013: 12 · 2012: 2
- FWCI
- 27.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Child Development (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Social Sciences › Psychology › Social Psychology › Social Robot Interaction and HRI
- Keywords
- theory of mind, children, temporoparietal junction, precuneus, medial prefrontal cortex, neural development, cognitive development, functional specialization, social cognition
- MeSH terms
- Acoustic Stimulation, Adolescent, Adult, Analysis of Variance, Brain, Child, Child, Preschool, Female, Humans, Functional Laterality, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Thinking, Young Adult, Theory of Mind
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