The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Acute hepatitis C in HIV-infected men who have sex with men.
Abstract
BACKGROUND: Hepatitis C virus (HCV) is usually transmitted via the parenteral route, but there are widely discrepant findings on its possible sexual transmission. Thus there are no recommendations concerning protected sex for couples in which only one partner is HCV-infected. Whether HIV or other sexually transmitted diseases could favour HCV transmission remains unclear, but recent data suggesting an increasing incidence of acute HCV in HIV-infected men underline the major public health implications of this issue. CASE REPORTS: Between June 2002 and July 2003, five HIV-infected homosexually active men presented with primary (n=4) and secondary (n=1) syphilis and concomitant abnormal liver function tests revealing acute asymptomatic HCV seroconversion. Other causes of acute viral hepatitis were inquired into and excluded. Highly at-risk sexual behaviour, including unprotected anal intercourse and unsafe oral sex, with concomitant syphilis, was found to be the only identifiable important risk factor for transmission of HCV. CONCLUSIONS: Sexual transmission may be fuelling a significant increase in HCV seroconversions among HIV-infected men who have highly risky sexual behaviours. Given the recent data suggesting the spread of sexually transmitted infections among HIV-infected gay men, specific recommendations concerning safe sex are urgently needed.
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“Certain studies have revealed that risk increases commensurate with increasing numbers of sex partners among heterosexual persons (1337,1338,1351–1353) and MSM with HIV infection (1349,1354–1357), especially if their partners are also coinfected with HIV (237,1340,1354–1356,1358).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1357]
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Metadata
- Authors
- Ghosn, J., Pierre‐François, S., Thibault, V, Duvivier, C., Tubiana, R., Simon, A., Valantin, M., Dominguez, S., Caumes, E., & Katlama, C.
- Affiliations
- Pitié-Salpêtrière Hospital (FR)
- Corresponding author
- Ghosn, J
- Venue
- HIV Medicine
- Publisher
- Wiley
- Published
- 2004-07
- Volume
- 5
- Issue
- 4
- Pages
- 303-306
- ISSN
- 1464-2662 (ISSN-L)
- 1468-1293
- OpenAlex
- W2050972803
- Cited by
- 111
- References
- 37
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 3 · 2021: 1 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 6 · 2012: 8
- FWCI
- 8.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- HIV Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- hepatitis C virus, acute hepatitis C, HIV infection, men who have sex with men, sexual transmission, syphilis, HCV seroconversion, unprotected anal intercourse, oral sex, sexually transmitted infections
- MeSH terms
- Acute Disease, Adult, Hepatitis C, Homosexuality, Humans, Male, Syphilis, HIV Infections, Disease Transmission, Infectious, Safe Sex
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