The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Acetylcholine and Choline in Neuronal Tissue Measured by HPLC with Electrochemical Detection
Abstract
Abstract: A simple, rapid method is presented for the determination of acetylcholine (ACh) and choline (Ch) in neuronal tissue using HPLC with electrochemical detection. The method is based on the separation of ACh and Ch by reverse‐phase HPLC and mixing the effluent as it emerges from the column with acetylcholinesterase and Ch oxidase, which converts endogenous Ch and Ch produced by the hydrolysis of ACh to betaine and hydrogen peroxide. Production of hydrogen peroxide is continuously monitored electrochemically. The sensitivity of the procedure is 1 pmol for Ch and 2 pmol for ACh. Specificity of the method is based on HPLC, two specific enzymatic reactions, and the detection of hydrogen peroxide.
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
Guidotti, A., Cheney, D. L., Trabucchi, M., Doteuchi, M., Wang, C., & Hawkins, R. A. (1974) · Neuropharmacology · doi:10.1016/0028-3908(74)90061-6 · Cited by 314
Purification and Characterization of Choline Oxidase from Arthrobacter globiformis
IKUTA, S., IMAMURA, S., MISAKI, H., & HORIUTI, Y. (1977) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a131872 · Cited by 229
Modern methods in pharmacology
Spector, S., & Back, N. (1982) · Medical Entomology and Zoology · Cited by 190
Israël, M., & Lesbats, B. (1981) · Neurochemistry International · doi:10.1016/0197-0186(81)90052-8 · Cited by 150
Cited by
Extraneuronal cholinergic system in lymphocytes
Kawashima, K. (2000) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(99)00071-6 · Cited by 384
Arnold, H. M., Burk, J. A., Hodgson, E. M., Sarter, M., & Bruno, J. P. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00292-0 · Cited by 195
Pedersen, W. A., Kloczewiak, M. A., & Blusztajn, J. K. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.8068 · Cited by 134
Prefrontal cortical modulation of acetylcholine release in posterior parietal cortex
Nelson, C. L., Sarter, M., & Bruno, J. P. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.007 · Cited by 128
NMDA and dopamine interactions in the nucleus accumbens modulate cortical acetylcholine release
Zmarowski, A., Sarter, M., & Bruno, J. P. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04333.x · Cited by 52
Metadata
- Authors
- Potter, P. E., Meek, J. L., & Neff, N. H.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 1983-01
- Volume
- 41
- Issue
- 1
- Pages
- 188-194
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W2152929301
- Cited by
- 409
- References
- 5
- FWCI
- 11.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- Potter, P. E., Meek, J. L., & Neff, N. H. (1983). Acetylcholine and Choline in Neuronal Tissue Measured by HPLC with Electrochemical Detection. Journal of Neurochemistry. https://doi.org/10.1111/j.1471-4159.1983.tb13668.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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