The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production
Abstract
Abstract: Measurements of calcium uptake and cyclic GMP production by cerebellar granule cells grown in primary culture demonstrated that ethanol preferentially inhibited N‐methyl‐D‐aspartate (NMDA) receptor‐gated cation channel function. Concentrations of ethanol as low as 10 m M inhibited NMDA‐stimulated Ca 2+ uptake by >30%, and ethanol also inhibited NMDA‐stimulated (Ca 2+‐dependent) cyclic GMP accumulation in a similar, dose‐dependent manner. Responses to kainate were significantly less sensitive to ethanol. Studies using various concentrations of NMDA, as well as phencyclidine (PCP) and glycine, suggested that ethanol affected the “coagonist” binding site of the NMDA receptor‐channel complex, rather than the PCP recognition site.
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Citations
Cites
NMDA application potentiates synaptic transmission in the hippocampus
Kauer, J. A., Malenka, R. C., & Nicoll, R. A. (1988) · Nature · doi:10.1038/334250a0 · Cited by 423
Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine
MacDonald, J. F., Miljkovic, Z., & Pennefather, P. (1987) · Journal of Neurophysiology · doi:10.1152/jn.1987.58.2.251 · Cited by 387
Cited by
Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain
Ikonomidou, C., Bosch, F., Miksa, M., Bittigau, P., Vöckler, J., Dikranian, K., Tenkova, T. I., Stefovska, V., Turski, L., & Olney, J. W. (1999) · Science · doi:10.1126/science.283.5398.70 · Cited by 2,055
Effects of Moderate Alcohol Consumption on the Central Nervous System*
Eckardt, M. J., File, S. E., Gessa, G. L., Grant, K. A., Guerri, C., Hoffman, P. L., Kalant, H., Koob, G. F., Li, T., & Tabakoff, B. (1998) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03695.x · Cited by 622
Self-citationNeurocircuitry Targets in Ethanol Reward and Dependence
Koob, G. F., Roberts, A. J., Schulteis, G., Parsons, L. H., Heyser, C. J., Hyyti??, P., Merlo-Pich, E., & Weiss, F. (1998) · Alcoholism: Clinical & Experimental Research · doi:10.1097/00000374-199802000-00001 · Cited by 560
Neurobiology of Addiction: Toward the Development of New Therapies
KOOB, G. F. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06682.x · Cited by 317
Metadata
- Authors
- Hoffman, P. L., Rabe, C. S., Moses, F., & Tabakoff, B.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 1989-06
- Volume
- 52
- Issue
- 6
- Pages
- 1937-1940
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W1994662713
- Cited by
- 566
- References
- 2
- FWCI
- 12.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hoffman, P. L., Rabe, C. S., Moses, F., & Tabakoff, B. (1989). N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production. Journal of Neurochemistry. https://doi.org/10.1111/j.1471-4159.1989.tb07280.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
