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Cited by 187

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Histologic Changes in Skin Associated with Aging

KURBAN, RAMSAY S., BHAWAN, JAG·1990·The Journal of Dermatologic Surgery and Oncology
DOI 10.1111/j.1524-4725.1990.tb01554.x
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Abstract

Abstract. This is a review of histologic changes noted in the skin of elderly individuals. Among the epidermal changes associated with skin aging are a flattened dermal‐epidermal junction, giving the appearance of atrophy and cellular heterogeneity. The melanocyte density declines slowly, and the Langerhans cells decrease in number with advancing age. Among the dermal changes are attenuation in the number and diameter of elastic fibers in the papillary dermis, an increase in number and thickness of the same fibers in the reticular dermis, and a coarsening of collagen fibers with an increase in density of the collagen network. A decrease in the dermal cell population as well as a functional decline in glandular activity are also noted with intrinsic aging. A decline in hair number, rate of growth, and diameter, along with a slowing of the rate of growth of nails, have been well documented with progressive aging.

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Crossref · 10.1111/j.1524-4725.1990.tb01554.x

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  • Age-associated histological changes are normally observed during physiological aging in multiple organs, including skin, spleen, kidneys, and stomach.

    “Age-associated histological changes are normally observed during physiological aging in multiple organs, including the skin, spleen, kidneys, and stomach”

    From In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming. (2016) · cites this paper as Kurban and Bhawan, 1990

Citations

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Research works printed but not linked: 59

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Metadata

Authors
KURBAN, R. S., & BHAWAN, J.
Venue
The Journal of Dermatologic Surgery and Oncology
Publisher
Wiley
Published
1990-10
Volume
16
Issue
10
Pages
908-914
ISSN
0148-0812
DOI
10.1111/j.1524-4725.1990.tb01554.x
Cited by
187
References
0
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 8299 d)

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