The influence of age and sex on skin thickness, skin collagen and density
Abstract
Forearm skin collagen, dermal thickness and collagen density were measured in a large number of normal subjects as a standard reference for future studies. Skin collagen decreased with age and was less in the females at all ages. There is a direct relationship between skin collagen and dermal thickness but variations in collagen density in disease limit the use of dermal thickness as a guide to changes in its collagen content.
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Skin thickness is a gender-dependent variable known to affect signal strength, and is observed to be higher in men than women across all age ranges.
“Skin thickness is another gender-dependent variable known to affect signal strength (as mentioned previously), and is observed to be higher in men than women across all age ranges [97,103].”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [103]
Shuster et al. measured skin thickness in 90 Caucasian men and 107 women and found that forearm skin thickness is greater in men than women, but no statistics were presented to explore statistical significance.
“Shuster et al. measured skin thickness in 90 Caucasian men and 107 women and found that forearm skin thickness is greater in men than women, but no statistics were presented to explore statistical significance [103].”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [103]
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- Authors
- SHUSTER, S., BLACK, M. M., & McVITIE, E.
- Affiliations
- Newcastle University (GB)
- ORCID
- SHUSTER, SAM
- Venue
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 1975-12
- Volume
- 93
- Issue
- 6
- Pages
- 639-643
- ISSN
- 0007-0963 (ISSN-L)
- 1365-2133
- OpenAlex
- W1981224048
- Cited by
- 640
- References
- 16
- Citations by year
- 2026: 15 · 2025: 34 · 2024: 25 · 2023: 39 · 2022: 33 · 2021: 32 · 2020: 24 · 2019: 29 · 2018: 27 · 2017: 28 · 2016: 21 · 2015: 30 · 2014: 23 · 2013: 23 · 2012: 19
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- British Journal of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Keywords
- skin collagen, skin thickness, collagen density, skin aging, sex differences, age differences, forearm skin, reference values
- MeSH terms
- Adolescent, Adult, Age Factors, Aged, Collagen, Female, Forearm, Humans, Male, Middle Aged, Sex Factors, Skin
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