Cited by 138Migraine and Headache StudiesTemporomandibular Joint DisordersPsychosomatic Disorders and Their Treatments

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

Headache and Psychiatric Comorbidity: Historical Context, Clinical Implications, and Research Relevance

Lake, Alvin E., Rains, Jeanetta C., Penzien, Donald B., Lipchik, Gay L.·2005·Headache: The Journal of Head and Face Pain

Abstract

The comorbidity of headache and psychiatric disorders is a well-recognized clinical phenomenon warranting further systematic research. Affective disorders occur with at least three-fold greater frequency among migraineurs than among the general population, and the prevalence increases in clinical populations, especially with chronic daily headache. When present, psychiatric comorbidity complicates headache management and portends a poorer prognosis for headache treatment. However, the relationship between headache and psychopathology has historically been misunderstood, and measures of psychopathology have not always met the standard of formal Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV) criteria. In some cases, headache has been inappropriately attributed to psychological or psychiatric features, based on anecdotal observations. The challenge for future studies is to employ research methods and designs that accurately identify and classify the subset of headache patients with psychiatric disorders, evaluate their impact on headache symptoms and treatment, and identify optimal behavioral and pharmacologic treatment strategies. This article offers methodological considerations and recommendations for future research including: (i) ascribing dual-International Classification of Headache Disorders, 2nd ed. (ICHD-2) headache and DSM-IV psychiatric diagnoses according to reliable and valid diagnostic criteria, (ii) differentiating subclinical levels of depression and anxiety from major psychiatric disorders, (iii) encouraging validation studies of the recently published ICHD-2 diagnoses for "headache attributed to psychiatric disorder," (iv) expanding epidemiological research to address the range of DSM-IV Axis I and II psychiatric diagnoses among various headache populations, (v) identifying relevant psychiatric and behavioral mediator/moderator variables, and (vi) developing empirically based screening and treatment algorithms.

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Crossref · 10.1111/j.1526-4610.2005.05101.x

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Research works printed but not linked: 11

  1. Penzien DB, 2005, The Headaches
  2. Italian Collaborative Group for the Study of Psychopathological Factors in Primary Headaches, 1999, Psychiatric comorbidity and psychosocial stress in patients with tension‐type headache from headache centers in Italy, Cephalalgia, 19, 159, 10.1046/j.1468-2982.1999.019003159.x · DOI
  3. Weissman MM, 1993, The epidemiology of personality disorders: a 1990 update, J Pers Disord, 7, 44
  4. Hegarty A, 1993, The prevalence of migraine in borderline personality disorder, Headache, 33, 271
  5. Lipchik GL, 2004, Migraine in Women, 144
  6. Saper JR, 2000, The Headaches, 953
  7. Holroyd KA, 2001, Patient characteristics predict response to antidepressant medication and to stress management therapy for chronic tension‐type headache, Cephalalgia, 21, 283
  8. Houle T, 2004, Biobehavioral precipitants of headache: time‐series analysis of stress and sleep on headache activity, Headache, 44, 533
  9. Penzien DB, 1999, Stress coping strategies of headache sufferers, Headache, 39, 374
  10. First MB, 1996, Structured Clinical Interview for DSM‐IV Axis I Disorders (SCID‐I): Clinician Version
  11. First MB, 1997, Structured Clinical Interview for DSM‐IV Personality Disorders (SCID‐II): Interview and Questionnaire

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Metadata

Authors
Lake, A. E., Rains, J. C., Penzien, D. B., & Lipchik, G. L.
Affiliations
Michigan Headache and Neurological Institute (US)
Venue
Headache: The Journal of Head and Face Pain
Publisher
Wiley
Published
2005-05
Volume
45
Issue
5
Pages
493-506
ISSN
  • 0017-8748 (ISSN-L)
  • 1526-4610
OpenAlex
W2063508612
Cited by
138
References
80
Citations by year
2026: 1 · 2025: 5 · 2024: 1 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 9 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 5 · 2012: 5
FWCI
9.40
Type
journal article
Language
en
Open access
closed
Locations
  • Headache The Journal of Head and Face Pain (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
  • Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
headache, psychiatric comorbidity, migraine, mood disorders, depression, anxiety, chronic daily headache, DSM-IV, diagnostic criteria, headache treatment
MeSH terms
Anxiety Disorders, Mental Disorders, Depressive Disorder, Humans, Personality Disorders, Research, Research Design, Comorbidity, Headache Disorders, History, 20th Century

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