Anticonvulsant Mechanisms of the Ketogenic Diet

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Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet

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Membrane Phospholipid Control of Nucleotide Sensitivity of K _ATP Channels

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POLYUNSATURATED FATTY ACID REGULATION OF GENES OF LIPID METABOLISM

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d -β-Hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease

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Physiological and pathophysiological roles of ATP-sensitive K+ channels

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A Multicenter Study of the Efficacy of the Ketogenic Diet

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Insulin, ketone bodies, and mitochondrial energy transduction

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2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP–dependent metabolic regulation of chromatin structure

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Ketone Bodies, Potential Therapeutic Uses

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Polyunsaturated Fatty Acid Regulation of Gene Expression

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The ketogenic diet increases mitochondrial uncoupling protein levels and activity

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Mechanisms Underlying the Cost of Living in Animals

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Medium‐chain triglycerides as a therapy for intractable childhood epilepsy

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Suppression of voltage-gated L-type Ca 2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes

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Mitochondrial uncoupling proteins in the cns: in support of function and survival

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Ketonemia and Seizures: Metabolic and Anticonvulsant Effects of Two Ketogenic Diets in Childhood Epilepsy

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A Modified Atkins Diet Is Effective for the Treatment of Intractable Pediatric Epilepsy

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α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification

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Protective Role of ATP-Sensitive Potassium Channels in Hypoxia-Induced Generalized Seizure

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Transport function and regulation of mitochondrial uncoupling proteins 2 and 3

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Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons.

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Experience With the Ketogenic Diet in Infants

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Cerebral ketone body metabolism

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Chronic ketosis and cerebral metabolism

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Efficacy of the Ketogenic Diet for Intractable Seizure Disorders: Review of 58 Cases

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Efficacy of the Atkins diet as therapy for intractable epilepsy

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Efficacy of the Ketogenic Diet as a Treatment Option for Epilepsy: Meta-analysis

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Pharmacology of neuronal background potassium channels

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Mitochondrial uncoupling protein‐2 protects the immature brain from excitotoxic neuronal death

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Polyunsaturated Fatty Acid Regulation of Gene Expression

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Efficacy of the Ketogenic Diet for Infantile Spasms

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Anticonvulsant and Antiepileptogenic Effects Mediated by Adeno-Associated Virus Vector Neuropeptide Y Expression in the Rat Hippocampus

Richichi, C., Lin, E.-J. D., Stefanin, D., Colella, D., Ravizza, T., Grignaschi, G., Veglianese, P., Sperk, G., During, M. J., & Vezzani, A. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4056-03.2004 · Cited by 234 · see citing works

The Ketogenic Diet for Intractable Epilepsy in Adults: Preliminary Results

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The TREK K2P channels and their role in general anaesthesia and neuroprotection

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The Ketogenic diet: from molecular mechanisms to clinical effects

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KETOGENIC DIETS IN THE TREATMENT OF EPILEPSY: SHORT‐TERM CLINICAL EFFECTS

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Growth of children on the ketogenic diet

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Caloric Restriction Inhibits Seizure Susceptibility in Epileptic EL Mice by Reducing Blood Glucose

Greene, A. E., Todorova, M. T., McGowan, R., & Seyfried, T. N. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.17601.x · Cited by 196 · see citing works

Uncoupling Protein 2 Prevents Neuronal Death Including that Occurring during Seizures: A Mechanism for Preconditioning

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Worldwide Use of the Ketogenic Diet

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Fatty acids suppress voltage-gated Na + currents in HEK293t cells transfected with the α-subunit of the human cardiac Na + channel

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Regulation of GABA Level in Rat Brain Synaptosomes: Fluxes Through Enzymes of the GABA Shunt and Effects of Glutamate, Calcium, and Ketone Bodies

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The role of norepinephrine in epilepsy: from the bench to the bedside

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Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet

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Omega-3 fatty acid supplementation in patients with chronic epilepsy: A randomized trial

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Prevention of sudden cardiac death by n−3 polyunsaturated fatty acids

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Diet Enriched with Omega‐3 Fatty Acids Alleviates Convulsion Symptoms in Epilepsy Patients

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Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies

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The role of catecholamines in seizure susceptibility: new results using genetically engineered mice

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The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy

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An Animal Model for the Ketogenic Diet

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Overexpression of NPY and Y2 receptors in epileptic brain tissue: an endogenous neuroprotective mechanism in temporal lobe epilepsy?

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The ketogenic diet in children, adolescents and young adults with refractory epilepsy: an Italian multicentric experience

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Acetoacetate, Acetone, and Dibenzylamine (a Contaminant in l ‐(+)‐β‐Hydroxybutyrate) Exhibit Direct Anticonvulsant Actions in Vivo

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Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet

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Seizure‐dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus

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A Ketogenic Diet Increases the Resistance to Pentylenetetrazole‐Induced Seizures in the Rat

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Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation

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Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission

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Free Radical–Mediated Cell Damage After Experimental Status Epilepticus in Hippocampal Slice Cultures

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Response of brain amino acid metabolism to ketosis

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Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet

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Neuronal–glial interactions in rats fed a ketogenic diet

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Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans

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Mechanisms underlying the anti-epileptic efficacy of the ketogenic diet

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Ketogenic Diet: Effects on Expression of Kindled Seizures and Behavior in Adult Rats

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Clinical efficacy of the ketogenic diet

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Anticonvulsant activity of a nonpeptide galanin receptor agonist

Saar, K., Mazarati, A. M., Mahlapuu, R., Hallnemo, G., Soomets, U., Kilk, K., Hellberg, S., Pooga, M., Tolf, B., Shi, T.-J. S., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102163499 · Cited by 129 · see citing works

The Glycolytic Enzymes, Glyceraldehyde-3-phosphate Dehydrogenase, Triose-phosphate Isomerase, and Pyruvate Kinase Are Components of the KATP Channel Macromolecular Complex and Regulate Its Function

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Calorie Restriction and Ketogenic Diet Diminish Neuronal Excitability in Rat Dentate Gyrus In Vivo

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Acetoacetate protects neuronal cells from oxidative glutamate toxicity

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Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat brain

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Dietary Fat, Ketosis, and Seizure Resistance in Rats on the Ketogenic Diet

Likhodii, S. S., Musa, K., Mendonça, A. J., Dell, C. A., Burnham, W. M., & Cunnane, S. C. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb00115.x · Cited by 124 · see citing works

METABOLIC EFFECTS OF THREE KETOGENIC DIETS IN THE TREATMENT OF SEVERE EPILEPSY

Schwartz, R. M., Boyes, S., & Aynsley-Green, A. (1989) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1989.tb03973.x · Cited by 121 · see citing works

The ketogenic diet; fatty acids, fatty acid-activated receptors and neurological disorders

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Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model

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Sodium Pump Activity, Not Glial Spatial Buffering, Clears Potassium After Epileptiform Activity Induced in the Dentate Gyrus

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Seizures Decrease Rapidly After Fasting

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The Ketogenic Diet: Adolescents Can Do It, Too

MADY, M., Kossoff, E. H., McGregor, A., Wheless, J. W., Pyzik, P. L., & Freeman, J. M. (2003) · Epilepsia · doi:10.1046/j.1528-1157.2003.57002.x · Cited by 110 · see citing works

ANTICONVULSANT PROPERTIES OF THE KETOGENIC DIET IN MICE

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Ketosis and Epilepsy: 31 P Spectroscopic Imaging at 4.1 T

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Diet‐Induced Ketosis Does Not Cause Cerebral Acidosis

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Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet

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Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death

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