The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Beef Fat Prevents Alcoholic Liver Disease in the Rat
Abstract
The amount and type of dietary fat is thought to be important in the pathogenesis of alcoholic liver disease (ALD). We investigated the role of different dietary fats in our rat model for ALD. Liver pathology was evaluated in rats fed ethanol and lard or tallow or corn oil over a period of 2 to 6 months. All experimental animals were pair‐fed the same diet as controls except that glucose was isocalorically replaced by ethanol. Rats fed tallow and ethanol developed none of the features of ALD, those fed lard and ethanol developed minimal to moderate disease, rats fed corn oil and ethanol developed the most severe pathology. The degree of histopathological abnormality correlated with the linoleic acid content of fat in the diet (tallow 0.7%, lard 2.5%, corn oil 56.6%). We postulate that linoleic acid facilitates development of ALD and provides an explanation for our previous epidemiological observations.
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Cites
Quantitative Relationship between Amount of Dietary Fat and Severity of Alcoholic Fatty Liver
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Self-citationReinke, L. A., Lai, E. K., DuBose, C. M., & McCay, P. B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9223 · Cited by 237
Histogenesis of alcoholic fibrosis and cirrhosis in the baboon.
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Long-term cannulation model for blood sampling and intragastric infusion in the rat
Tsukamoto, H., Reidelberger, R. D., French, S. W., & Largman, C. (1984) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1984.247.3.r595 · Cited by 179
Self-citationEffects of ethanol ingestion and dietary fat levels on mitochondrial lipids in male and female rats
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Ethanol‐Induced Hepatic Fibrosis in the Rat: Role of the Amount of Dietary Fat
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Self-citationCentrilobular Liver Necrosis Induced by Hypoxia in Chronic Ethanol-Fed Rats
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Antibiotics prevent liver injury in rats following long-term exposure to ethanol
Adachi, Y., Moore, L. E., Bradford, B. U., Gao, W., & Thurman, R. G. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90027-6 · Cited by 692
NADPH oxidase–derived free radicals are key oxidants in alcohol-induced liver disease
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Toll–Like Receptor 4 Is Involved in the Mechanism of Early Alcohol–Induced Liver Injury in Mice
Uesugi, T., Froh, M., Arteel, G. E., Bradford, B. U., & Thurman, R. G. (2001) · Hepatology · doi:10.1053/jhep.2001.25350 · Cited by 488
Nanji, A. A., Zhao, S., Sadrzadeh, S. M. H., Dannenberg, A. J., Tahan, S. R., & Waxman, D. J. (1994) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1994.tb00119.x · Cited by 261
Self-citationYou, M., Considine, R. V., Leone, T. C., Kelly, D. P., & Crabb, D. W. (2005) · Hepatology · doi:10.1002/hep.20821 · Cited by 259
Metadata
- Authors
- Nanji, A. A., Mendenhall, C. L., & French, S. W.
- Venue
- Alcoholism: Clinical and Experimental Research
- Publisher
- Wiley
- Published
- 1989-02
- Volume
- 13
- Issue
- 1
- Pages
- 15-19
- ISSN
- 0145-6008 (ISSN-L)
- 1530-0277
- OpenAlex
- W2016411116
- Cited by
- 276
- References
- 16
- FWCI
- 5.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nanji, A. A., Mendenhall, C. L., & French, S. W. (1989). Beef Fat Prevents Alcoholic Liver Disease in the Rat. Alcoholism: Clinical and Experimental Research. https://doi.org/10.1111/j.1530-0277.1989.tb00276.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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