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Cited by 1,632

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

AUDIT‐C as a Brief Screen for Alcohol Misuse in Primary Care

Bradley, Katharine A., DeBenedetti, Anna F., Volk, Robert J., Williams, Emily C., Frank, Danielle, Kivlahan, Daniel R.·2007·Alcoholism: Clinical and Experimental Research

Abstract

Background: The Alcohol Use Disorders Identification Test Consumption (AUDIT‐C) questions have been previously validated as a 3‐item screen for alcohol misuse and implemented nationwide in Veterans Affairs (VA) outpatient clinics. However, the AUDIT‐C's validity and optimal screening threshold(s) in other clinical populations are unknown. Methods: This cross‐sectional validation study compared screening questionnaires with standardized interviews in 392 male and 927 female adult outpatients at an academic family practice clinic from 1993 to 1994. The AUDIT‐C, full AUDIT, self‐reported risky drinking, AUDIT question #3, and an augmented CAGE questionnaire were compared with an interview primary reference standard of alcohol misuse, defined as a Diagnostic and Statistical Manual, 4th ed. alcohol use disorder and/or drinking above recommended limits in the past year. Results: Based on interviews with 92% of eligible patients, 128 (33%) men and 177 (19%) women met the criteria for alcohol misuse. Areas under the receiver operating characteristic curves (AUROCs) for the AUDIT‐C were 0.94 (0.91, 0.96) and 0.90 (0.87, 0.93) in men and women, respectively (p=0.04). Based on AUROC curves, the AUDIT‐C performed as well as the full AUDIT and significantly better than self‐reported risky drinking, AUDIT question #3, or the augmented CAGE questionnaire (p‐values <0.001). The AUDIT‐C screening thresholds that simultaneously maximized sensitivity and specificity were ≥4 in men (sensitivity 0.86, specificity 0.89) and ≥3 in women (sensitivity 0.73, specificity 0.91). Conclusions: The AUDIT‐C was an effective screening test for alcohol misuse in this primary care sample. Optimal screening thresholds for alcohol misuse among men (≥4) and women (≥3) were the same as in previously published VA studies.

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Research works printed but not linked: 6

  1. Babor TF, 1989, AUDIT: Alcohol Use Disorders Identification Test: Guidelines for Use in Primary Health Care
  2. Bradley KA, 2006, Implementation of evidence‐based alcohol screening in the Veteran Affairs healthcare system, Am J Manag Care, 12, 597
  3. National Institute on Alcohol Abuse and Alcoholism and National Institutes of Health, 2003, Helping Patients With Alcohol Problems: A Practitioner's Guide
  4. Saitz R, 2003, Alcohol and medication interactions in primary care patients, common and unrecognized, 114, 407
  5. Vinson DC, 1997, Alcohol is not a dichotomous variable (editorial), J Fam Pract, 44, 147
  6. 10.1111/j.1360-0443.1997.tb03652.x · doi:10.1111/j.1360-0443.1997.tb03652.x · Paper page

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Metadata

Authors
Bradley, K. A., DeBenedetti, A. F., Volk, R. J., Williams, E. C., Frank, D., & Kivlahan, D. R.
Venue
Alcoholism: Clinical and Experimental Research
Publisher
Wiley
Published
2007-04-19
Volume
31
Issue
7
Pages
1208-1217
ISSN
  • 0145-6008 (ISSN-L)
  • 1530-0277
OpenAlex
W2098658501
Cited by
1,632
References
48
FWCI
15.07
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: AUDIT‐C as a Brief Screen for Alcohol Misuse in Primary Care. https://app.cochat.ai/papers/10.1111/j.1530-0277.2007.00403.x
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Bradley, K. A., DeBenedetti, A. F., Volk, R. J., Williams, E. C., Frank, D., & Kivlahan, D. R. (2007). AUDIT‐C as a Brief Screen for Alcohol Misuse in Primary Care. Alcoholism: Clinical and Experimental Research. https://doi.org/10.1111/j.1530-0277.2007.00403.x

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