The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Comparison of Frailty Indicators Based on Clinical Phenotype and the Multiple Deficit Approach in Predicting Mortality and Physical Limitation
Abstract
Objectives: To compare three simple bedside tools based on frailty phenotypes with a Frailty Index using the multiple deficit approach in the prediction of mortality and physical limitation after 4 years. Design: Cohort study. Setting: Hong Kong, China. Pariticipants: Four thousand men and women aged 65 and older living in the community who were ambulatory enough to attend the study center. Methods: Interviewers obtained information regarding physical, psychological, and functional health; body mass index ( BMI ), grip strength, blood pressure, and ankle brachial index were determined. Three clinical frailty scales based on the Fried phenotype (Cardiovascular Health Study ( CHS ); Fatigue, Resistance, Ambulation, Illness, and Loss ( FRAIL ); and Hubbard) and a frailty index ( FI ) were constructed from these variables, and their ability to predict incident mortality and physical function limitations was compared using receiver operating characteristic ( ROC ) curves. Results: All tools predicted adverse outcomes. More participants were categorized into frail and prefrail categories using the CHS than with the other two clinical scales. For all frailty measures, with increasing levels of frailty, the sensitivity fell and the specificity increased to greater than 90%; the area under the ROC curve values were approximately 0.6. Conclusion: Simple frailty scores are comparable with a multidimensional deficit accumulation FI in predicting mortality and physical limitations. The newer FRAIL , proposed for use in a clinical setting, is comparable with other existing short screening tools, as well as tools based on the multiple‐deficits model used for research settings. Addition of a physical performance measure to screening tools may increase predictive accuracy.
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Citations
Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
Development and validation of a geriatric depression screening scale: a preliminary report
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Accumulation of Deficits as a Proxy Measure of Aging
Mitnitski, A. B., Mogilner, A. J., & Rockwood, K. (2001) · The Scientific World JOURNAL · doi:10.1100/tsw.2001.58 · Cited by 2,893
Validity and reliability of the Edmonton Frail Scale
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A comparison of two approaches to measuring frailty in elderly people
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“A three-item score comprising weight loss of 5% or more, inability to rise from a chain five times without using the arms, and poor energy (answer of no to the question, “Do you feel full of energy?” was used in the Study of Osteoporotic Fractures (SOF) and compared with the CHS scale.(11) Both scores classify partici…”
MethodKulminski, A. M., Ukraintseva, S. V., Kulminskaya, I. V., Arbeev, K. G., Land, K., & Yashin, A. I. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01656.x · Cited by 434
Low Free Testosterone Predicts Frailty in Older Men: The Health in Men Study
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Cited by
McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab670 · Cited by 19,442
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw128 · Cited by 11,429
2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure
Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.592 · Cited by 5,866
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., et al. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.021 · Cited by 2,553
Self-citationPhysical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management
Dent, E., Morley, J. E., Cruz-Jentoft, A. J., Woodhouse, L., Rodríguez-Mañas, L., Fried, L. P., Woo, J., Aprahamian, I., Sanford, A., Lundy, J., et al. (2019) · The Journal of nutrition, health and aging · doi:10.1007/s12603-019-1273-z · Cited by 1,049
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Metadata
- Authors
- Woo, J., Leung, J., & Morley, J. E.
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2012-08
- Volume
- 60
- Issue
- 8
- Pages
- 1478-1486
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- OpenAlex
- W2041135039
- Cited by
- 385
- References
- 13
- FWCI
- 13.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Woo, J., Leung, J., & Morley, J. E. (2012). Comparison of Frailty Indicators Based on Clinical Phenotype and the Multiple Deficit Approach in Predicting Mortality and Physical Limitation. Journal of the American Geriatrics Society. https://doi.org/10.1111/j.1532-5415.2012.04074.x
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