Primary antiphospholipid syndrome in pregnancy: an analysis of outcome in a cohort of 33 women treated with a rigorous protocol
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In observational studies, LDA plus therapeutic dose heparin was associated with live births in 79% of pregnancies on average.
“In observational studies, treatment with LDA and therapeutic dose heparin was associated with live births in 79% of pregnancies on average.52 61–64”
From EULAR recommendations for the management of antiphospholipid syndrome in adults (2019) · cites this paper as [61]
Cites
Rai, R., Cohen, H., Dave, M., & Regan, L. (1997) · BMJ · doi:10.1136/bmj.314.7076.253 · Cited by 1,113 · see citing works
Cowchock, F. S., Reece, E. A., Balaban, D. J., Branch, D. W., & Plouffe, L. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(92)91596-3 · Cited by 585 · see citing works
(1992) · PubMed · Cited by 434 · see citing works
Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment
Farquharson, R. G. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(02)02165-8 · Cited by 429 · see citing works
Harrington, K., Cooper, D., Lees, C. C., Hecher, K., & Campbell, S. C. (1996) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1996.07030182.x · Cited by 351 · see citing works
Branch, D. W., Peaceman, A. M., Druzin, M. L., Silver, R. K., El-Sayed, Y. Y., Silver, R. M., Esplin, M. S., Spinnato, J. A., & Harger, J. H. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(00)70500-x · Cited by 315 · see citing works
(1996) · PubMed · Cited by 307 · see citing works
Management of the obstetric antiphospholipid syndrome
Derksen, R. H. W. M., Khamashta, M. A., & Branch, D. W. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20105 · Cited by 200 · see citing works
Self-citationAntiphospholipid Syndrome in Pregnancy
Farquharson, R. G., Quenby, S. M., & Greaves, M. (2002) · Obstetrics and Gynecology · doi:10.1097/00006250-200212000-00032 · Cited by 96 · see citing works
Thromboprophylaxis During Pregnancy, Labour and After Vaginal Delivery
Fouda, A. (2011) · Cited by 58 · see citing works
Hunt, B. J., Khamashta, M. A., Lakasing, L., Williams, F. M. K., Nelson‐Piercy, C., Bewley, S., & Hughes, G. R. V. (1998) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1615124 · Cited by 34 · see citing works
Self-citationObstetric Antiphospholipid Syndrome
Porter, T. F., Silver, R. M., & Branch, D. W. (2006) · Springer eBooks · doi:10.1007/1-84628-009-5_17 · Cited by 13 · see citing works
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EULAR recommendations for the management of antiphospholipid syndrome in adults
Tektonidou, M. G., Andreoli, L., Limper, M., Amoura, Z., Cervera, R., Costedoat-Chalumeau, N., Cuadrado, M. J., Dörner, T., Ferrer-Oliveras, R., Hambly, K., et al. (2019) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2019-215213 · Cited by 1,261 · see citing works
“52 61–64 Because a history of thrombotic APS is associated with increased risk for future thrombotic or obstetric events, 65 treatment with LDA and heparin at therapeutic dosage during pregnancy is recommended.”
Self-citationPregnancy outcome in different clinical phenotypes of antiphospholipid syndrome
Bramham, K., Hunt, B., Germain, S., Calatayud, I., Khamashta, M., Bewley, S., & Nelson-Piercy, C. (2010) · Lupus · doi:10.1177/0961203309347794 · Cited by 185 · see citing works
Self-citationFirst-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss
Bramham, K., Thomas, M., Nelson-Piercy, C., Khamashta, M., & Hunt, B. J. (2011) · Blood · doi:10.1182/blood-2011-02-339234 · Cited by 180 · see citing works
Self-citationFischer-Betz, R., Specker, C., Brinks, R., & Schneider, M. (2012) · Lupus · doi:10.1177/0961203312451335 · Cited by 56 · see citing works
Naru, T., Khan, R. S., & Ali, R. (2010) · Eastern Mediterranean Health Journal · doi:10.26719/2010.16.3.308 · Cited by 15 · see citing works
- Authors
- STONE, S., HUNT, B. J., KHAMASHTA, M. A., BEWLEY, S. J., & NELSON‐PIERCY, C.
- Affiliations
- King's College London (GB)
- Guy's Hospital (GB)
- Corresponding author
- HUNT, B.J.
- Venue
- Journal of Thrombosis and Haemostasis
- Publisher
- Elsevier BV
- Published
- 2005-02
- Volume
- 3
- Issue
- 2
- Pages
- 243-245
- ISSN
- 1538-7836 (ISSN-L)
- OpenAlex
- W2056788755
- Cited by
- 49
- References
- 12
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2021: 4 · 2020: 4 · 2019: 4 · 2018: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2012: 2
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Thrombosis and Haemostasis (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- LUPUS UK
- Topics
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- primary antiphospholipid syndrome, pregnancy, recurrent pregnancy loss, placental insufficiency, fetal growth restriction, fetal death, preeclampsia, placental abruption, preterm birth, pregnancy outcomes
- MeSH terms
- Adult, Cesarean Section, Female, Fibrinolytic Agents, Follow-Up Studies, Humans, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Premedication, Cohort Studies, Antiphospholipid Syndrome
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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