Influence of different IgG anticardiolipin antibody cut‐off values on antiphospholipid syndrome classification

International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)

MIYAKIS, S., LOCKSHIN, M. D., ATSUMI, T., BRANCH, D. W., BREY, R. L., CERVERA, R., DERKSEN, R. H. W. M., DE GROOT, P. G., KOIKE, T., MERONI, P. L., et al. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.01753.x · Cited by 7,203

Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH.

Brandt, J. T., Triplett, D. A., Alving, B. M., & Scharrer, I. (1995) · PubMed · Cited by 1,164

Evaluation of the anti-cardiolipin antibody test: report of an international workshop held 4 April 1986.

Harris, E. N., Gharavi, A. E., Patel, S., & Hughes, G. R. (1987) · PubMed Central · Cited by 724

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

Girardi, G., Berman, J., Redecha, P. B., Spruce, L. A., Thurman, J. M., Kraus, D., Hollmann, T. J., Casali, P., Caroll, M. C., Wetsel, R. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18817 · Cited by 691

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

Girardi, G., Berman, J., Redecha, P. B., Spruce, L. A., Thurman, J. M., Kraus, D., Hollmann, T. J., Casali, P., Caroll, M. C., Wetsel, R. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200318817 · Cited by 593

Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: a four‐year prospective study from the Italian Registry

Finazzi, G., Brancaccio, V., Moia, M., Ciavarella, N., Mazzucconi, M. G., Schinco, P., Ruggeri, M., Pogliani, E. M., Gamba, G., Rossi, E., et al. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(96)00060-5 · Cited by 427

IgG Anticardiolipin Antibody Titer >40 GPL and the Risk of Subsequent Thrombo-occlusive Events and Death

Levine, S. R., Salowich‐Palm, L., Sawaya, K. L., Perry, M., Spencer, H. J., Winkler, H. J., Alam, Z., & Carey, J. L. (1997) · Stroke · doi:10.1161/01.str.28.9.1660 · Cited by 212

Excessive complement activation is associated with placental injury in patients with antiphospholipid antibodies

Shamonki, J. M., Salmon, J. E., Hyjek, E. M., & Baergen, R. N. (2007) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.10.879 · Cited by 203

Prevalence of lupus anticoagulant and anticardiolipin antibodies in a healthy population

Shi, W., Krilis, S., Chong, B. H., Gordon, S., & Chesterman, C. N. (1990) · Australian and New Zealand Journal of Medicine · doi:10.1111/j.1445-5994.1990.tb01025.x · Cited by 196

Anticardiolipin Antibody Assay: a Methodological Analysis for a better Consensus in Routine Determinations

Allegri, F., Sanmarco, M., Cinquini, M., Taglietti, M., Balestrieri, G., Koike, T., Ichikawa, K., Meroni, P. L., Boffa, M. C., & Tincani, A. (2001) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1616089 · Cited by 182

THE IX EUROPEAN FORUM ON ANTIPHOSPHOLIPID ANTIBODIES. A BRIEF REVIEW

Seredavkina, N. V., & Reshetnyak, T. M. (2014) · Rheumatology Science and Practice · doi:10.14412/1995-4484-2014-115-121 · Cited by 3

Antiphospholipid antibodies quantification using ALBIA technology: how to define an optimal cutoff?

Cabrera-Marante, Ó., Lora, D., Serrano, M., de Frías, E. R., Naranjo, L., Pérez, M. D., Paz‐Artal, E., Pleguezuelo, D. E., & Serrano, A. (2021) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2021-0394 · Cited by 3

Location of recurrent cardiovascular events and anticardiolipin antibodies

Galán‐González, J., Rico‐Martín, S., García, J. F. C., Antón, J., Ramírez-Moreno, J. M., Álvarez, L. R., Muñoz-Torrero, J. F. S., & for FRENA Investigators (2021) · European Journal of Clinical Investigation · doi:10.1111/eci.13533 · Cited by 3

Analytical Detection Capabilities of Immunoassay‐Based Antiphospholipid Antibody Tests: Do They Matter?

Lakos, G. (2013) · Drug Development Research · doi:10.1002/ddr.21117 · Cited by 3

Critical Update of the Antiphospholipid Syndrome Criteria

Pengo, V., & Ruffatti, A. (2010) · The Open Autoimmunity Journal · Cited by 3

Association of anticardiolipin, antiphosphatidylserine, anti-β2 glycoprotein I, and antiphosphatidylcholine autoantibodies with canine immune thrombocytopenia

Chen, Y., Chi, L., Chow, K., Chiou, S.-H., Fan, Y.-H., Ho, S.-P., Hsu, Y., Hwang, Y.-C., Wu, M.-X., Lee, W., et al. (2016) · BMC Veterinary Research · doi:10.1186/s12917-016-0727-3 · Cited by 3

Antiphospholipid Antibody Syndrome-Diagnostic Issues of Lupus Anticoagulants

Tyagi, S., & Ahuja, A. (2016) · Journal of Hematology & Thromboembolic Diseases · doi:10.4172/2329-8790.1000253 · Cited by 3

The absence of standardization in antiphospholipid antibody testing may favor the use of 99th percentile cutoffs in antiphospholipid syndrome classification

Anunciación-Llunell, A., Marques-Soares, J. R., Očková, M., Pozuelo, N. F., Esteve‐Valverde, E., Andrada, C., Alijotas‐Reig, J., & Miró‐Mur, F. (2025) · Research and Practice in Thrombosis and Haemostasis · doi:10.1016/j.rpth.2025.102967 · Cited by 2

Study of antiphospholipid antibodies by enzyme immunoassay and chemiluminescent methods in patients with antiphospholipid syndrome and systemic lupus erythematosus (preliminary data)

Cheldieva, F. A., Reshetnyak, T. M., Cherkasova, M. V., & Lila, A. M. (2021) · Russian Clinical Laboratory Diagnostics · doi:10.51620/0869-2084-2021-66-9-546-551 · Cited by 2

Determination of the 99th percentile of anticardiolipin and anti-β2 glycoprotein I antibodies in an institution in the city of Medellin, Colombia

Castilla-Agudelo, G. A., Padilla, L. M. R., Velásquez, S., Zapata, L. J. H., Navas, M. A. M., Barreneche, M. F. Á., & Franco, C. J. V. (2024) · Revista Colombiana de Reumatología (English Edition) · doi:10.1016/j.rcreue.2022.01.003 · Cited by 1

Is the 99th Percentile Cutoff Still Relevant? A Single-Center Assessment of Different Thresholds for Diagnosing Antiphospholipid Syndrome

Dadelahi, A., Walker, B. S., Banerjee, D., Mähler, M., Saadalla, A. M., & Nandakumar, V. (2024) · The Journal of Applied Laboratory Medicine · doi:10.1093/jalm/jfae149 · Cited by 1

Navigating obstetric antiphospholipid syndrome: pathophysiology, diagnosis, and therapeutic advances

Aldabie, G., Almarzooqi, A. M., Aljohani, R., Altawash, M. M., Alkadi, A., & Khamashta, M. A. (2026) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2025.2612589 · Cited by 1

Antiphospholipid Syndrome: Changing Knowledge During the Time – The ”Four P” Pattern

Buliková, A. (2012) · InTech eBooks · doi:10.5772/49097 · Cited by 1

Characteristics of Chinese patients with antiphospholipid syndrome and the ability of lupus anticoagulant assays to identify them

Tang, N., Sun, Z., & Yin, S. (2016) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2016-0129 · Cited by 1

Significato clinico degli anticorpi anti acido lisobisfosfatidico nei pazienti con sindrome da antifosfolipidi primaria Clinical value of antibodies to lysobisphosphatidic acid in patients with primary antiphospholipid sindrome

Olivieri, S., Ruffatti, A., Bontadi, A., Cavazzana, A., Salvan, E., Cuffaro, S., Giunco, S., Punzi, L., & Medica, C. (2010) · Cited by 1

Diagnosis of antiphospholipid syndrome: From an historical perspective to the emergence of new autoantibodies

Ardila-Suarez, O., Gómez-Puerta, J. A., & Khamashta, M. A. (2016) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2016.07.016 · Cited by 1

Classification Criteria for the Antiphospholipid Syndrome

Derksen, R. H. W. M., & Fritsch-Stork, R. D. E. (2014) · Rare diseases of the immune system · doi:10.1007/978-3-319-11044-8_5 · Cited by 1

Antiphospholipid Antibodies and Syndrome

Cervera, R. (2018) · MDPI eBooks · doi:10.3390/books978-3-03842-948-7 · Cited by 3

Pregnancy Morbidity Associated with Thrombophilias: Late Placenta-Mediated Obstetric Complications

Veerareddy, S., Clesham, K., Cohen, H., & Peebles, D. (2015) · Springer eBooks · doi:10.1007/978-3-319-15120-5_8

Antiphospholipid Antibodies – Detection and Clinical Importance

Swadźba, J., & Kolodziejczyk, J. (2012) · InTech eBooks · doi:10.5772/30530

Confirmation of antiphospholipid antibody positivity: a year’s results in a cohort of 113 patients

Cuffaro, S., Ross, T. D., Tonello, M., Bontadi, A., Olivieri, S., Salvan, E., Ruffatti, A., & Punzi, L. (2011) · Reumatismo · doi:10.4081/reumatismo.2010.51

The future of treatment for antiphospholipid syndrome

Willis, R., Harris, E. N., & Pierangeli, S. S. (2014) · International Journal of Clinical Rheumatology · doi:10.2217/ijr.13.73

Task Force Report on “Non-criteria” Antiphospholipid Antibody Tests

Bertolaccini, M. L., Amengual, O., Atsumi, T., Binder, W. L., Kutteh, W. H., de Laat, B., Forastiero, R. R., Lambert, M., Matsubayashi, H., Murthy, V. L., et al. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3194-7_8

Comparison of modern analyzers for the detection of antiphospholipid antibodies in patients with SLE

Vossen, D., Hofbauer, M., Kersten, J. F., Krieger, T., Peine, S., & Gutensohn, K. (2013) · Journal of Laboratory Medicine · doi:10.1515/labmed-2012-0076

Profils cliniques et biologiques associés à la persistance des anticorps antiphospholipides au-delà de douze semaines

Roy, G. L. (2015) · HAL

Pertinence clinique de la détection précoce des anticorps anti-adalimumab dans la polyarthrite rhumatoïde, la spondylarthrite ankylosante et le rhumatisme psoriasique : étude multicentrique prospective

Hoxha, A., Calligaro, A., Tonello, M., Ramonda, R., Carletto, A., Paolazzi, G., Bortolotti, R., Ross, T. D., Grava, C., Boaretto, M., et al. (2016) · Revue du Rhumatisme · doi:10.1016/j.rhum.2016.11.007

Antiphospholipid Antibodies and Reproduction

Sammaritano, L. R. (2017) · Cambridge University Press eBooks · doi:10.1017/9781139976787.012

路上的彩虹——天虹摩托车TH90—B真叫我满意

袁建辉 (1996) · 摩托车

Determinación del percentil 99 de los anticuerpos anticardiolipina y anti-β2 glicoproteína I en una institución en la ciudad de Medellín, Colombia

Castilla-Agudelo, G. A., Padilla, L. M. R., Velásquez, S., Zapata, L. J. H., Navas, M. A. M., Barreneche, M. F. Á., & Franco, C. J. V. (2022) · Revista Colombiana de Reumatología · doi:10.1016/j.rcreu.2022.01.003

Antiphospholipid Syndrome: Changing Knowledge During the Time – The ”Four P” Pattern

Buliková, A. (2012) · InTech eBooks · doi:10.5772/47107

Does incomplete obstetric antiphospholipid syndrome really exist?

Alijotas‐Reig, J. (2021) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2020.12.018

Task Force Report on “Criteria” Antiphospholipid Antibody Tests

Roubey, R. A. S., & Pierangeli, S. S. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3194-7_7

Comprehensive evaluation of antiphospholipid antibody testing methodologies in APS diagnosis: performance comparisons across assay systems and clinical subtypes

Wang, Y., Xu, Y., Wang, T., Wei, W., Chen, R., Ouyang, R., Wang, F., Hou, H., & Wu, S. (2025) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2025-0499 · Cited by 1

Population-specific antiphospholipid antibody titres in a South Indian cohort: defining cut-off values and implications for diagnosis from a cross-sectional validation study

Bhaskaran, H., Mithun, C., Visalakshy, J., Surendran, S., Gayathri, S., Bhaskaran, R., Easwar, S. V., & Pradeep, M. (2026) · BMC Rheumatology · doi:10.1186/s41927-026-00636-w

Influence of anticardiolipin and anti‐β2 glycoprotein I antibody cutoff values on antiphospholipid syndrome classification

Vanoverschelde, L., Kelchtermans, H., Musial, J., de Laat, B., & Devreese, K. M. J. (2019) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12207 · Cited by 33

Antiphospholipid syndrome classification criteria: comments on the letter of Swadzba and Musial

Ruffatti, A., & Pengo, V. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03277.x · Cited by 4

More on: the debate on antiphospholipid syndrome classification criteria

Swadźba, J., & Musiał, J. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03274.x · Cited by 13

Anticardiolipin and anti-β2glycoprotein-I antibody cut-off values in the diagnosis of antiphospholipid syndrome: more than calculating the in-house 99th percentiles, even for new automated assays

Devreese, K. M. J., & Van Hoecke, F. (2011) · Thrombosis Research · doi:10.1016/j.thromres.2011.06.023 · Cited by 32

The anticardiolipin assay is required for sensitive screening for antiphospholipid antibodies

Nash, M. J., Camilleri, R. S., Kunka, S., Mackie, I. J., Machin, S. J., & Cohen, H. (2004) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2004.00810.x · Cited by 64