Adverse Drug Reactions in Women's Health Care
Abstract
Adverse drug reactions (ADRs) are drug‐related adverse events that occur in individuals using usual or therapeutic doses of medication. Women have a nearly 2‐fold greater risk for developing ADRs than men, and they are more likely to be hospitalized secondary to an ADR. This article reviews the physiologic mechanisms of ADRs, common clinical manifestations of ADRs to medications often prescribed in women's health care, documentation and reporting of ADRs, and ADR prevention strategies.
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Zolpidem shows slower drug metabolization and high secondary effects in women, increasing their health risks compared with men.
“zolpidem, a sleep medication35, which shows slower drug metabolization and high secondary effects in women, increasing their health risks compared with men34,36,37.”
From Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare (2020) · cites this paper as [34]
Sex differences in drug physiology, together with underrepresentation of women in clinical trials, can explain why women typically report more adverse event reactions compared with men.
“These differences, taken together with the underrepresentation of women in clinical trials, can explain why women typically report more adverse event reactions compared with men34.”
From Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare (2020) · cites this paper as [34]
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- Authors
- Tharpe, N.
- Affiliations
- Philadelphia University (US)
- Corresponding author
- Tharpe, Nell
- ORCID
- Tharpe, Nell
- Venue
- Journal of Midwifery & Women's Health
- Publisher
- Wiley
- Published
- 2011-04-28
- Volume
- 56
- Issue
- 3
- Pages
- 205-213
- ISSN
- 1526-9523 (ISSN-L)
- 1542-2011
- OpenAlex
- W2169597261
- Cited by
- 64
- References
- 28
- Citations by year
- 2026: 1 · 2025: 8 · 2024: 10 · 2023: 8 · 2022: 4 · 2021: 11 · 2020: 6 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 2 · 2014: 2 · 2013: 1
- FWCI
- 0.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Midwifery & Women s Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
- Keywords
- adverse drug reactions, women's health services, sex differences in drug response, adverse drug reaction reporting, ADR prevention, hospitalization
- MeSH terms
- Female, Humans, Male, Risk Factors, Sex Factors, United States, United States Food and Drug Administration, Women's Health, Adverse Drug Reaction Reporting Systems, Drug-Related Side Effects and Adverse Reactions
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