The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi: Genomic comparison of S. Typhimurium and S. Typhi
Abstract
Salmonella enterica represents a major human and animal pathogen. Many S. enterica genomes have been completed and many more genome sequencing projects are underway, constituting an excellent resource for comparative genome analysis studies leading to a better understanding of bacterial evolution and pathogenesis. Salmonella enterica serovar Typhimurium and Typhi are the best-characterized serovars, with the first being involved in localized gastroenteritis in many hosts and the latter causing a systemic human-specific disease. Here, we summarize the major genetic differences between the two different serovars. We detail the divergent repertoires of the virulence factors responsible for the pathogenesis of the organisms and that ultimately result in the distinct clinical outcomes of infection. This comparative genomic overview highlights hypotheses for future investigations on S. enterica pathogenesis and the basis of host specificity.
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Determining Divergence Times of the Major Kingdoms of Living Organisms with a Protein Clock
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Cited by
Jajere, S. M. (2019) · Veterinary World · doi:10.14202/vetworld.2019.504-521 · Cited by 621
Salmonella enterica Serovar Typhi and the Pathogenesis of Typhoid Fever
Dougan, G., & Baker, S. (2014) · Annual Review of Microbiology · doi:10.1146/annurev-micro-091313-103739 · Cited by 338
Host Adaptation of a Bacterial Toxin from the Human Pathogen Salmonella Typhi
Deng, L., Song, J., Gao, X., Wang, J., Yu, H., Chen, X., Varki, N., Naito-Matsui, Y., Galán, J. E., & Varki, A. (2014) · Cell · doi:10.1016/j.cell.2014.10.057 · Cited by 120
Chaudhary, J. H., Nayak, J. B., Brahmbhatt, M. N., & Makwana, P. P. (2015) · Veterinary World · doi:10.14202/vetworld.2015.121-124 · Cited by 77
Karlinsey, J. E., Stepien, T. A., Mayho, M., Singletary, L. A., Bingham-Ramos, L. K., Brehm, M. A., Greiner, D. L., Shultz, L. D., Gallagher, L. A., Bawn, M., et al. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.08.001 · Cited by 56
Metadata
- Authors
- Sabbagh, S. C., Forest, C. G., Lepage, C., Leclerc, J.-M., & Daigle, F.
- Venue
- FEMS Microbiology Letters
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-03-04
- Volume
- 305
- Issue
- 1
- Pages
- 1-13
- ISSN
- 0378-1097 (ISSN-L)
- 1574-6968
- OpenAlex
- W1911152711
- Cited by
- 269
- References
- 4
- FWCI
- 22.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi: Genomic comparison of S. Typhimurium and S. Typhi. https://app.cochat.ai/papers/10.1111/j.1574-6968.2010.01904.x
- The paper
- Sabbagh, S. C., Forest, C. G., Lepage, C., Leclerc, J.-M., & Daigle, F. (2010). So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi: Genomic comparison of S. Typhimurium and S. Typhi. FEMS Microbiology Letters. https://doi.org/10.1111/j.1574-6968.2010.01904.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
