The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis
Abstract
The soil-dwelling bacterium Bacillus subtilis differentiates into distinct subpopulations of specialized cells that coexist within highly structured communities. The coordination and interplay between these cell types requires extensive extracellular communication driven mostly by sensing self-generated secreted signals. These extracellular signals activate a set of sensor kinases, which respond by phosphorylating three major regulatory proteins, Spo0A, DegU and ComA. Each phosphorylated regulator triggers a specific differentiation program while at the same time repressing other differentiation programs. This allows a cell to differentiate in response to a specific cue, even in the presence of other, possibly conflicting, signals. The sensor kinases involved respond to an eclectic group of extracellular signals, such as quorum-sensing molecules, natural products, temperature, pH or scarcity of nutrients. This article reviews the cascades of cell differentiation pathways that are triggered by sensing extracellular signals. We also present a tentative developmental model in which the diverse cell types sequentially differentiate to achieve the proper development of the bacterial community.
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Cites
Fruiting body formation by Bacillus subtilis
Branda, S. S., González-Pastor, J. E., Ben-Yehuda, S., Losick, R., & Kolter, R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.191384198 · Cited by 1,129
Self-citationENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON
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Quadri, L. E. N., Weinreb, P. H., Lei, M., Nakano, M. M., Zuber, P., & Walsh, C. T. (1998) · Biochemistry · doi:10.1021/bi9719861 · Cited by 693
Eymann, C., Homuth, G., Scharf, C., & Hecker, M. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.9.2500-2520.2002 · Cited by 306
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BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm
Hobley, L., Ostrowski, A., Rao, F. V., Bromley, K. M., Porter, M., Prescott, A. R., MacPhee, C. E., van Aalten, D. M. F., & Stanley-Wall, N. R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306390110 · Cited by 294
Ryall, B., Eydallin, G., & Ferenci, T. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05028-11 · Cited by 160
Should the biofilm mode of life be taken into consideration for microbial biocontrol agents?
Pandin, C., Le Coq, D., Canette, A., Aymerich, S., & Briandet, R. (2017) · Microbial Biotechnology · doi:10.1111/1751-7915.12693 · Cited by 157
Construction and description of a constitutive plipastatin mono-producing Bacillus subtilis
Vahidinasab, M., Lilge, L., Reinfurt, A., Pfannstiel, J., Henkel, M., Morabbi Heravi, K., & Hausmann, R. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01468-0 · Cited by 68
Metadata
- Authors
- López, D., & Kolter, R.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-03
- Volume
- 34
- Issue
- 2
- Pages
- 134-149
- ISSN
- 0168-6445 (ISSN-L)
- 1574-6976
- OpenAlex
- W2044128702
- Cited by
- 286
- References
- 4
- FWCI
- 8.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- López, D., & Kolter, R. (2010). Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis. FEMS Microbiology Reviews. https://doi.org/10.1111/j.1574-6976.2009.00199.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
