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Cited by 324

The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.

Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin system

Open access
Docheva, Denitsa, Popov, Cvetan, Mutschler, Wolf, Schieker, Matthias·2007·Journal of Cellular and Molecular Medicine

Abstract

Mesenchymal stem cells and their clinical relevance Integrins and their importance Cell surface molecules on MSCs Integrin system of MSCs Engagement of integrins in MSC differentiation, attachment to coating materials, survival on scaffolds and neoplastic transformation Conclusions The identification of mesenchymal stem cells (MSCs) in adult human tissues and the disclosure of their self‐renew‐al and multi‐lineage differentiation capabilities have provided exciting prospects for cell‐based regeneration and tis‐sue engineering. Although a considerable amount of data is available describing MSCs, there is still lack of information regarding the molecular mechanisms that govern their adhesion and migration. In this work, we will review the current state of knowledge on integrins and other adhesion molecules found to be expressed on MSCs. The dis‐cussed topics include the characteristics of MSCs and their clinical applications, integrins and their central role in cell‐matrix attachment and migration, and comments on mobilization, differentiation and contribution to tumour development. Finally, by understanding the complex and fundamental pathways by which MSCs attach and migrate, it might be possible to fine‐tune the strategies for effective and safe use of MSCs in regenerative therapies.

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Integrity signals

Registry

Crossref · 10.1111/j.1582-4934.2007.00001.x

Cites

96 of 96 references verified0 citation errors · 0 not checkable

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Citations

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Metadata

Authors
Docheva, D., Popov, C., Mutschler, W., & Schieker, M.
Venue
Journal of Cellular and Molecular Medicine
Publisher
Wiley
Published
2007-01
Volume
11
Issue
1
Pages
21-38
ISSN
  • 1582-1838 (ISSN-L)
  • 1582-4934
OpenAlex
W2060341044
Cited by
324
References
96
FWCI
9.73
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin system. https://app.cochat.ai/papers/10.1111/j.1582-4934.2007.00001.x
The paper
Docheva, D., Popov, C., Mutschler, W., & Schieker, M. (2007). Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin system. Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/j.1582-4934.2007.00001.x

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.