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Increased apolipoprotein B serum concentration in Alzheimer's disease
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In AD patients, LDL-cholesterol and apoB concentrations are increased, and correlate with brain Aβ concentrations.
“In AD patients, LDL-cholesterol and apoB concentrations are increased, and correlate with brain Aβ concentrations [31], [32], [33].”
From ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage (2011) · cites this paper as [32]
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- Corder, 1993, Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late-onset families, Science, 261, 921, 10.1126/science.8346443 · DOI · Paper page
- Nalbantoglu, 1994, Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies, Ann Neurol, 36, 889, 10.1002/ana.410360614 · DOI
- Mahley, 1988, Apolipoprotein E: cholesterol transport protein with expanding role in cell biology, Science, 240, 622, 10.1126/science.3283935 · DOI · Paper page
- Hixson, 1991, Research Group. Apolipoprotein E polymorphisms affect atherosclerosis in young males, Arterioscler Thromb, 11, 1237, 10.1161/01.ATV.11.5.1237 · DOI
- Eichner, 1993, Relation of Apolipoprotein E phenotype to myocardial infarction and mortality from coronary artery disease, Am J Cardiol, 71, 160, 10.1016/0002-9149(93)90732-R · DOI
- Bockxmeer, 1992, Apolipoprotein ɛ4 homozygosity in young men with coronary heart disease, Lancet, 340, 879, 10.1016/0140-6736(92)93288-X · DOI
- Kosunen, 1995, Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients, Stroke, 26, 743, 10.1161/01.STR.26.5.743 · DOI
- Sparks, 1990, Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease, Neurobiol Aging, 11, 601, 10.1016/0197-4580(90)90024-T · DOI
- Hofman, 1997, Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study, Lancet, 349, 151, 10.1016/S0140-6736(96)09328-2 · DOI · Paper page
- Giubilei, 1990, Serum lipoprotein pattern variation in dementia and ischemic stroke, Acta Neurol Scand, 81, 84, 10.1111/j.1600-0404.1990.tb00936.x · DOI
- Kotter, 1996, Total serum cholesterol in patients with Alzheimer's disease and healthy controls, Neurobiol Aging, 17, S95, 10.1016/S0197-4580(96)80384-8 · DOI
- McKhann, 1984, Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease, Neurology, 34, 939, 10.1212/WNL.34.7.939 · DOI · Paper page
- Havel, The Metabolic and Molecular Bases of Inherited Diseases, 1841
- Lamarche, 1997, Small, dense, low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from Québec Cardiovascular Study, Circulation, 95, 69, 10.1161/01.CIR.95.1.69 · DOI · Paper page
- Steinberg, 1988, Metabolism of lipoproteins and their role in the pathogenesis of atherosclerosis, Atherosclerosis Rev, 18, 1
- Namba, 1992, Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease, Neurosci Lett, 134, 264, 10.1016/0304-3940(92)90531-B · DOI
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Metadata
- Authors
- Caramelli, P., Nitrini, R., Maranhão, R., Lourenço, A. C. G., Damasceno, M. C., Vinagre, C., & Caramelli, B.
- Venue
- Acta Neurologica Scandinavica
- Publisher
- Hindawi Limited
- Published
- 1999-07
- Volume
- 100
- Issue
- 1
- Pages
- 61-63
- ISSN
- 0001-6314
- 1600-0404
- Cited by
- 74
- References
- 0
- Language
- en
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