The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Paroxetine efficacy in the treatment of generalized anxiety disorder
Abstract
Recently, there has been a renewed interest in alternatives to the benzodiazepines for the treatment of generalized anxiety disorder (GAD). The aim of the present study was to compare the efficacy of paroxetine vs. imipramine and 2′‐chlordesmethyldiazepam in 81 patients with a DSM‐IV diagnosis of GAD. Approximately two‐thirds of the patients who completed the study improved greatly or moderately on all three active drugs. During the first 2 weeks of treatment, 2′‐chlordesmethyldiazepam treatment resulted in the greatest improvement in anxiety ratings. Both paroxetine and imipramine treatment resulted in more improvement than 2′‐chlordesmethyldiazepam by the fourth week of treatment. Paroxetine and imipramine affect predominantly psychic symptoms, whereas 2′‐chlordesmethyldiazepam affects predominantly somatic symptoms. Our results suggest that paroxetine is effective for the treatment of GAD.
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Cites
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Cited by
Katzman, M. A., Bleau, P., Blier, P., Chokka, P., Kjernisted, K., Van Ameringen, M., & the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-s1-s1 · Cited by 1,090
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Metadata
- Authors
- Rocca, P., Fonzo, V., Scotta, M., Zanalda, E., & Ravizza, L.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 1997-05
- Volume
- 95
- Issue
- 5
- Pages
- 444-450
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W2136635083
- Cited by
- 194
- References
- 3
- FWCI
- 16.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rocca, P., Fonzo, V., Scotta, M., Zanalda, E., & Ravizza, L. (1997). Paroxetine efficacy in the treatment of generalized anxiety disorder. Acta Psychiatrica Scandinavica. https://doi.org/10.1111/j.1600-0447.1997.tb09660.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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