The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The incidence and severity of nifedipine‐induced gingival overgrowth
Abstract
Abstract The gingival health of 19 patients with cardiovascular problems who were medicated with nifedipine was compared with a similar cohort treated with atenolol and a control group of healthy patients. In the nifedipine and atenolol groups, patients had been taking their respective medication for a minimum period of 6 months. Plaque scores were similar for all three groups. However, patients medicated with nifedipine had a significantly higher gingival index (P < 0.005), gingival overgrowth scores (P <0.02) and probing sites >3 mm (P < 0.005) when compared with the atenolol and control groups. 4 patients in the nifedipine group experienced clinically significant gingival overgrowth which required surgical excision. Gingival changes in the nifedipine patients were not related to drug dosage or plaque scores. It is concluded that nifedipine therapy results in significant gingival changes, an effect which may be mediated by the drug's action on calcium transport.
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Cites
Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition
Silness, J., & Löe, H. (1964) · Acta Odontologica Scandinavica · doi:10.3109/00016356408993968 · Cited by 7,932
Cited by
The pathogenesis of drug‐induced gingival overgrowth
Seymour, R. A., Thomason, J. M., & Ellis, J. S. (1996) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1996.tb02072.x · Cited by 403
Self-citationDental plaque-induced gingival conditions
Murakami, S., Mealey, B. L., Mariotti, A., & Chapple, I. L. C. (2018) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12937 · Cited by 358
Dental Plaque‐Induced Gingival Diseases
Mariotti, A. (1999) · Annals of Periodontology · doi:10.1902/annals.1999.4.1.7 · Cited by 332
Prevalence of Gingival Overgrowth Induced by Calcium Channel Blockers: A Community‐Based Study
Ellis, J. S., Seymour, R. A., Steele, J. G., Robertson, P., Butler, T. J., & Thomason, J. M. (1999) · Journal of Periodontology · doi:10.1902/jop.1999.70.1.63 · Cited by 273
Self-citationHallmon, W. W., & Rossmann, J. A. (1999) · Periodontology 2000 · doi:10.1111/j.1600-0757.1999.tb00175.x · Cited by 148
Metadata
- Authors
- Barclay, S., Thomason, J. M., Idle, J. R., & Seymour, R. A.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 1992-05
- Volume
- 19
- Issue
- 5
- Pages
- 311-314
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2023461584
- Cited by
- 191
- References
- 1
- FWCI
- 26.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- Barclay, S., Thomason, J. M., Idle, J. R., & Seymour, R. A. (1992). The incidence and severity of nifedipine‐induced gingival overgrowth. Journal of Clinical Periodontology. https://doi.org/10.1111/j.1600-051x.1992.tb00650.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
